The functional insight into the genetics of cardiovascular disease: results from the post-GWAS study [0.03%]
GWAS研究之后关于心血管疾病遗传学的功能洞察研究结果
L O Bryzgalov,E E Korbolina,I S Damarov et al.
L O Bryzgalov et al.
Cardiovascular diseases (CVDs), the leading cause of death worldwide, generally refer to a range of pathological conditions with the involvement of the heart and the blood vessels. A sizable fraction of the susceptibility loci is known, but...
Dynamic changes in betanin content during the growing season of table beet: their interplay with abiotic factors [0.03%]
盐渍条件下甜菜生长季甜菜红素含量动态变化及其与非生物因子的互作关系研究
D V Sokolova
D V Sokolova
The table beet, a widespread edible root crop known for its medicinal and antioxidant properties, early maturation, good shelf life, and high contents of bioactive compounds, vitamins and minerals, is used for the production of a natural re...
Association between ТР53, MDM2 and NQO1 gene polymorphisms and viral load among women with human papillomavirus [0.03%]
与人乳头瘤病毒感染者病毒载量相关的TP53、MDM2和NQO1基因多态性关联研究
A H AlBosale,E V Mashkina
A H AlBosale
The risk of cervical cancer is caused by persistent human papillomavirus (HPV) infection. Cervical cancer is the most frequent cancer among women. Our purpose was to investigate the association between TP53 215C>G (Pro72Arg), MDM2 -410T>G, ...
A bioinformatic search for correspondence between differentially expressed genes of domestic versus wild animals and orthologous human genes altering reproductive potential [0.03%]
家养动物与野生動物差异表达基因及其同源人类生殖潜能改变基因的生物信息学分析
M P Ponomarenko,I V Chadaeva,P M Ponomarenko et al.
M P Ponomarenko et al.
One of the greatest achievements of genetics in the 20th century is D.K. Belyaev's discovery of destabilizing selection during the domestication of animals and that this selection affects only gene expression regulation (not gene structure)...
M S Ermakov,A A Nushtaeva,V A Richter et al.
M S Ermakov et al.
The stromal elements of a malignant tumor can promote cancer progression and metastasis. The structure of the tumor stroma includes connective tissue elements, blood vessels, nerves, and extracellular matrix (ECM). Some of the cellular elem...
De novo assembly and analysis of the transcriptome of the Siberian wood frog Rana amurensis [0.03%]
东北林蛙(Rana amurensis)转录组从头组装及分析
D N Smirnov,S V Shekhovtsov,A A Shipova et al.
D N Smirnov et al.
The Siberian wood frog Rana amurensis Boulenger, 1886 is the most hypoxia-tolerant amphibian. It can survive for several months in an almost complete absence of oxygen. Little is known about the mechanisms of this remarkable resilience, in ...
DNA metabarcoding of benthic algae and associated eukaryotes from Lake Baikal in the face of rapid environmental changes [0.03%]
面对快速环境变化的贝加尔湖底藻类和相关的真核生物的DNA metabarcoding
Yu S Bukin,L S Kravtsova,T E Peretolchina et al.
Yu S Bukin et al.
Here we report new data describing the biodiversity of phytobenthic communities based on DNA-metabarcoding using the 18S rDNA marker and the Illumina MiSeq system. The study was initiated due to the blooming of f ilamentous algae (mainly of...
Phosphoryl guanidine oligonucleotides as primers for RNA-dependent DNA synthesis using murine leukemia virus reverse transcriptase [0.03%]
以鼠白血病病毒逆转录酶催化合成DNA的RNA依赖型寡核苷酸引物-磷酸瓜尔宁碱型
E S Dyudeeva,I A Pyshnaya
E S Dyudeeva
Modern approaches to the detection and analysis of low-copy-number RNAs are often based on the use of RNA-dependent DNA polymerases, for example, in reverse-transcription PCR. The accuracy and eff iciency of cDNA synthesis in the reverse-tr...
Transcriptional activity of repair, apoptosis and cell cycle genes (TP53, MDM2, ATM, BAX, BCL-2, CDKN1A, OGG1, XPC, PADI4, MAPK8, NF-KB1, STAT3, GATA3) in chronically exposed persons with different intensity of apoptosis of peripheral blood lymphocytes [0.03%]
慢性暴露人群外周血淋巴细胞凋亡强度不同者修复、凋亡和细胞周期相关基因（TP53，MDM2，ATM，BAX，BCL-2，CDKN1A，OGG1，XPC，PADI4，MAPK8，NF-KB1，STAT3，GATA3）转录活性不同
V S Nikiforov,E A Blinova,A I Kotikova et al.
V S Nikiforov et al.
Transcriptional activity of genes involved in maintaining genetic homeostasis (genes for repair, cell cycle and apoptosis: TP53, MDM2, ATM, BAX, BCL-2, CDKN1A, OGG1, XPC, PADI4, MAPK8, NF-KB1, STAT3, GATA3) was studied in chronically expose...
Scientific breeding of winter bread wheat in the Non-Сhernozem zone of Russia: the history, methods and results [0.03%]
俄罗斯非黑钙土区冬小麦品种改良的历史、方法及结果
B I Sandukhadze,R Z Mamedov,M S Krakhmalyova et al.
B I Sandukhadze et al.
The article describes the main stages and achievements of the breeding of winter bread wheat (Triticum aestivum L.) in the Non-Chernozem zone for more than a century. The beginning of breeding work was laid by D.L. Rudzinsky on the experime...