Gene networks and metabolomic screening analysis revealed specific pathways of amino acid and acylcarnitine profile alterations in blood plasma of patients with Parkinson's disease and vascular parkinsonism [0.03%]
基因网络和代谢组学筛查分析揭示了帕金森病和血管性帕金森病患者血浆中氨基酸和酰基肉碱谱变化的特定途径
A A Makarova,P M Melnikova,A D Rogachev et al.
A A Makarova et al.
Parkinson's disease (PD) and vascular parkinsonism (VP) are characterized by similar neurological syndromes but differ in pathogenesis, morphology, and therapeutic approaches. The molecular genetic mechanisms of these pathologies are multif...
Generation and characterization of two induced pluripotent stem cell lines (ICGi052-A and ICGi052-B) from a patient with frontotemporal dementia with parkinsonism-17 associated with the pathological variant c.2013T>G in the MAPT gene [0.03%]
由MAPT基因病理变异c.2013T>G相关额颞痴呆伴帕金森病患者建立的两个诱导多能干细胞系(ICGi052-A和ICGi052-B)的建立及鉴定
E V Grigor&#x;eva,A A Malakhova,E S Yarkova et al.
E V Grigor&#x;eva et al.
Frontotemporal dementia with parkinsonism-17 is a neurodegenerative disease characterised by pathological aggregation of the tau protein with the formation of neurofibrillary tangles and subsequent neuronal death. The inherited form of fron...
Cytogenetic features of intergeneric amphydiploids and genome-substituted forms of wheat [0.03%]
小麦属间 amphidiploid及基因组置换系的细胞遗传特征研究
E D Badaeva,R O Davoyan,N A Tereshchenko et al.
E D Badaeva et al.
Synthetic intergeneric amphydiploids and genome-substituted wheat forms are an important source for transferring agronomically valuable genes from wild species into the common wheat (Triticum aestivum L.) genome. They can be used both in ac...
R R Savchenko,N A Skryabin
R R Savchenko
Our understanding of human genes - particularly their structure, functions, and regulatory mechanisms - is still limited. The biological role of approximately 20 % of human proteins has not been established yet, and the molecular functions ...
Detailed cytogenetic analysis of three duck species (the northern pintail, mallard, and common goldeneye) and karyotype evolution in the family Anatidae (Anseriformes, Aves) [0.03%]
三种鸭（北方针尾鸭、绿头鸭和黄金眼）的详细细胞遗传分析及雁形目鸭科动物染色体进化研究
V R Beklemisheva,K V Tishakova,S A Romanenko et al.
V R Beklemisheva et al.
Galliformes and Anseriformes are two branches of the Galloanserae group, basal to other Neognathae. In contrast to Galliformes, Anseriformes have not been thoroughly researched by cytogenetic methods. This report is focused on representativ...
Polymorphic variants of the genes for enzymes of the antioxidant system, apoptosis and inflammation as potential predictors of myocardial infarction [0.03%]
抗氧化系统、凋亡和炎症相关酶多态性基因作为心肌梗死潜在预测因素的研究
T R Nasibullin,V V Erdman,Y R Timasheva et al.
T R Nasibullin et al.
Myocardial infarction (MI) is a multifactorial polygenic disease that develops as a result of a complex interaction of numerous genetic factors and the external environment. Accordingly, the contribution of each of them separately is usuall...
The concept of natural genome reconstruction.Part 1. Basic provisions of the "natural genome reconstruction" concept. Changing the genome of hematopoietic stem cells using several natural cellular mechanisms that are inherent in the hematopoietic cell and determine its biological status as "the source of the body's re [0.03%]
从天然基因组重建的概念出发（一）天然基因组重建概念的基本规定及造血干细胞基因组的天然性细胞改变 механизмов, которые естественны для клеток кроветворения и определяют их биологус|已完成翻译
L A Yakubov,O S Taranov,S V Sidorov et al.
L A Yakubov et al.
We present a series of articles proving the existence of a previously unknown mechanism of interaction between hematopoietic stem cells and extracellular double-stranded DNA (and, in particular, double-stranded DNA of the peripheral bloodst...
Molecular genetic and morphological characteristics of Micractinium thermotolerans and M. inermum (Trebouxiophyceae, Chlorophyta) from pyroclastic deposits of the Kamchatka Peninsula (Russia) [0.03%]
俄罗斯堪察加半岛火山碎屑沉积物中Micractinium thermotolerans和M. inermum（Trebouxiophyceae，Chlorophyta）的分子遗传和形态特征
R Z Sushchenko,V Yu Nikulin,V B Bagmet et al.
R Z Sushchenko et al.
During the study of algal diversity in pyroclastic deposits of the Kamchatka Peninsula, Chlorella-like green algae strains VCA-72 and VCA-93 were isolated from samples collected from along the Baydarnaya river bed on the Shiveluch volcano i...
The potential of the amaranth collection maintained at VIR in the context of global plant breeding and utilization trends [0.03%]
VIR何藜芦属种质资源在全球植物育种和利用趋势下的应用前景
D V Sokolova,A E Solovieva,A M Zaretsky et al.
D V Sokolova et al.
Amaranth is an ancient crop of the family Amaranthaceae, but it is fairly new to Russia. Its seeds and leaf biomass contain a high-quality gluten-free protein, fatty acids, squalene (a polyunsaturated hydrocarbon), flavonoids, vitamins, and...
Comparative analysis of the primary structure and production of recombinant poly(ADP-ribose)polymerase 1 of long-lived Heterocephalus glaber [0.03%]
长寿裸鼹润滑鼠端粒酶逆转录酶的初级结构比较分析及其人重组聚（腺苷二磷酸-核糖）聚合酶1的表达与鉴定
K N Naumenko,A R Nurislamov,K D Nazarov et al.
K N Naumenko et al.
DNA repair is a most important cellular process that helps maintain the integrity of the genome and is currently considered by researchers as one of the factors determining the maximum lifespan. The central regulator of the DNA repair proce...