The liver-brain axis under the influence of chronic Opisthorchis felineus infection combined with prolonged alcoholization in mice [0.03%]
慢性Opisthorchis felineus感染合并长期酒精化小鼠的肝脑轴研究
D F Avgustinovich,I V Chadaeva,A V Kizimenko et al.
D F Avgustinovich et al.
Our purpose was to model a combination of a prolonged consumption of ethanol with Opisthorchis felineus infection in mice. Four groups of C57BL/6 mice were compiled: OF, mice infected with O. felineus for 6 months; Eth, mice consuming 20 % ...
A V Smirnov,A N Korablev,I A Serova et al.
A V Smirnov et al.
In pronuclear microinjection, the Cas9 endonuclease is employed to introduce in vivo DNA double-strand breaks at the genomic target locus or within the donor vector, thereby enhancing transgene integration. The manner by which Cas9 interact...
Genetic characteristics of local horse breeds by microsatellite DNA loci [0.03%]
微卫星DNA标记检测地方马种的遗传特性
N V Blohina,L A Khrabrova
N V Blohina
Russia has a significant pedigree diversity of horse breeds with unique gene pools that are well adapted to a wide variety of harsh natural and climatic conditions, are characterized by universal performance and high productive qualities, a...
Interrelations between the main seed quality characteristics of narrowleaf lupine from the VIR collection [0.03%]
维理收集的窄叶羽扇豆主要种子质量特征之间的相互关系
T V Shelenga,A V Salikova,V S Popov et al.
T V Shelenga et al.
The widespread use of narrowleaf lupine (NLL, Lupinus angustifolius L.) as a feed and food crop requires source material for breeding cultivars with high-quality seeds. The priority criterion for attributing NLL cultivars to the feed or foo...
D Malkeyeva,E V Kiseleva,S A Fedorova
D Malkeyeva
Throughout their lives, cells synthesise new and dispose of the old, denatured proteins and insoluble protein aggregates. An important role in maintaining proteostasis is played by chaperones, which fold various proteins and promote degrada...
Generation and characterisation of seven induced pluripotent stem cell lines from two patients with Parkinson's disease carrying the pathological variant c.1087G>T of the LGR4 gene [0.03%]
来自携带LGR4基因c.1087G>T致病变异的两位帕金森病患者的七株诱导多能干细胞系的生成和特征分析
V S Podvysotskaya,E V Grigor&#x;eva,A A Malakhova et al.
V S Podvysotskaya et al.
Parkinson's disease is a neurodegenerative disorder affecting dopaminergic neurons of the substantia nigra pars compacta. The known pathological genetic variants may explain the cause of only 5 % of cases of the disease. In our study, we fo...
Association of two missense mutations in the MSS51 and KAT6B genes with body weight at different ages in cows of the Yaroslavl breed [0.03%]
Yaroslavl牛不同年龄体重与MSS51和KAT6B基因两个错义突变的关联性研究
A V Igoshin,N S Yudin,D M Larkin
A V Igoshin
The Yaroslavl cattle is a native Russian dairy breed developed in the 19th century from the Northern Great Russian cattle, which were adapted to withstand harsh climates and poor forage conditions. Previous studies identified two breed-spec...
The role of SELE gene polymorphism in ST-elevation myocardial infarction [0.03%]
SELE基因多态性在ST段抬高型心肌梗死中的作用
N P Babushkina,A M Nikolaeva,A D Dolbnya et al.
N P Babushkina et al.
Ischemic heart disease (IHD) is an important medical and social problem. ST-elevation myocardial infarction (STEMI) is the most severe form of IHD, affecting all layers of the heart muscle. One of the diagnostic criteria for endothelial dys...
Analysis of similarities and differences of accessions belonging to Prunus domestica L. and P. insititia L. using endocarp dimensions and shape variations [0.03%]
利用内果皮尺寸和形状变异分析属于Prunus domestica L. 和P. insititia L. 的材料的相似性和差异性
T Milošević,N Milošević
T Milošević
The endocarp or stone is the most stable morphological feature of the genus Prunus. However, the identification of plum types, groups and/or genotypes based on endocarp is complicated because of a wide range of variation and morphological t...
Comparative analysis of haplotypes carrying pathogenic variants c.1545T>G, c.2027T>A and c.919-2A>G of the SLC26A4 gene in patients with hearing loss from the Tyva Republic (Southern Siberia) [0.03%]
来自图瓦共和国（西伯利亚南部）听力损失患者的SLC26A4基因携带有害变异c.1545T>G, c.2027T>A和c.919-2A>G的单倍型的比较分析
V Yu Danilchenko,M V Zytsar,E A Panina et al.
V Yu Danilchenko et al.
Pathogenic variants in the SLC26A4 gene (OMIM #605646), leading to non-syndromic recessive hearing loss type 4 (DFNB4) and Pendred syndrome, significantly contribute to the etiology of hearing loss in many populations of the world. The spec...