Arterial shear rate determines the structure and mechanical properties of whole-blood clots [0.03%]
动脉剪切率决定了全血凝块的结构和机械性能
Hande Eyisoylu,Parvin Ebrahimi,Marla Lavrijsen et al.
Hande Eyisoylu et al.
Background: Arterial thrombosis arises under high shear conditions and is a leading cause of ischemic stroke and myocardial infarction. The local hemodynamic environment during the formation of the thrombus influences its...
Performance evaluation of a reflexive algorithm for suspected heparin-induced thrombocytopenia [0.03%]
怀疑肝素诱导的血小板减少症的反射性算法性能评价
Sean G Yates,Christopher B Webb,Lisa M Scheid et al.
Sean G Yates et al.
Background: The diagnostic workup of heparin-induced thrombocytopenia (HIT) involves a heparin-platelet factor 4 complex-dependent screening test, such as an enzyme-linked immunosorbent assay (ELISA) or a rapid latex immu...
Analysis of causes and outcomes of principal secondary thrombotic microangiopathy: a 9-year cohort study from a tertiary pediatric center in China [0.03%]
中国一家三级儿科中心9年间主要继发性血栓性微血管病病因和转归的分析研究
Dan Wu,Jie Zheng,Jun Yang et al.
Dan Wu et al.
Background: Few large-scale cohort studies have reviewed consecutive cases of thrombotic microangiopathy (TMA), especially in children. Objectives: ...
Perioperative management of direct oral anticoagulant-treated patients who need urgent surgery [0.03%]
直接口服抗凝药物治疗患者需行紧急手术时的围术期管理
Stephanie Carlin,Alejandro Godoy,James Douketis
Stephanie Carlin
Quality of life and functional recovery after venous stent placement for postthrombotic syndrome: insights from the ARIVA multinational randomized trial [0.03%]
静脉支架置入治疗血栓后综合征的生存质量及功能恢复情况——来自ARIVA多国随机试验的启示
Stefano Barco,Simon Wolf,Tim Sebastian et al.
Stefano Barco et al.
Background: Postthrombotic syndrome (PTS) is a disabling complication of deep vein thrombosis and is associated with impaired functional status. Objective...
Randomized Controlled Trial
Research and practice in thrombosis and haemostasis. 2026 Jul 10;10(5):106828. DOI:10.1016/j.rpth.2026.106828 2026
Multigene panel analysis of connective tissue and vascular genes in patients with a bleeding disorder of unknown cause or a cerebrovascular event [0.03%]
针对病因不明的出血性疾病或脑血管事件患者进行连接组织和血管基因多基因检测分析
Mona Florquin,Christine Van Laer,Cyrielle Kint et al.
Mona Florquin et al.
Background: Bleeding disorder of unknown cause (BDUC) refers to patients with a significant bleeding phenotype despite normal hemostatic evaluation. Cerebrovascular events (CVEs) are neurologic deficits from intracerebral...
Evaluation and application of automated quality control in clinical coagulation testing [0.03%]
临床凝血检验中自动化质量控制的应用及评价
Yanli Liang,Hongtao Zhang,Sihan Zhao et al.
Yanli Liang et al.
Background: Internal quality control (IQC) is indispensable for ensuring the accuracy of clinical laboratory testing. While fully automated track systems have enabled standardized IQC for clinical chemistry and hematology...
Biological clocks and blood clots in space: circadian disruption-induced modulation of thrombosis risk [0.03%]
生物钟与太空中的血液凝结：昼夜节律紊乱引起的血栓风险变化
Zeinab Ibrahim,Ronan P Murphy,Germaine Cornelissen Guillaume et al.
Zeinab Ibrahim et al.
Long-duration space missions expose astronauts to microgravity, radiation, confinement, fluid redistribution, and circadian disruption, which together induce physiological adaptations, including cardiovascular hemodynamics. Emerging evidenc...
Identification of a protein S-binding site in the C2 domain of factor VIII light chain [0.03%]
在因子VIII轻链C2结构域中识别结合蛋白S的位点
Shoko Furukawa,Masahiro Takeyama,Keiji Nogami
Shoko Furukawa
Background: We demonstrated that protein S (PS) directly impairs the intrinsic tenase complex, independent of activated protein C (APC), by competitively inhibiting the binding of factor (F)IXa to the A2 domain (residues ...
Prognostic value of von Willebrand factor and ADAMTS-13 in patients with sepsis-induced coagulopathy [0.03%]
血管性血友病因子和ADAMTS-13在脓毒症凝血病患者中的预后价值分析
Feng Zhang,Yuting Li,Yanhua Li et al.
Feng Zhang et al.
Background: The von Willebrand factor (VWF)- a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13 (ADAMTS-13) axis may contribute to microvascular thrombosis and poor outcomes in sepsis-induced ...