7-Methylguanine With a Cyclopentane Backbone: A Bright Combination for a FIT-PNA RNA Sensor [0.03%]
7-甲基鸟嘌呤与环戊烷骨架的组合：适配体-FIT-PNA 传感器中的亮色搭配
Salam Maree,Pinaki Chanda,Sheethal Thomas Mannully et al.
Salam Maree et al.
FIT-PNAs (forced intercalation-Peptide Nucleic Acids) are promising RNA sensors due to the enhanced fluorescence gained by such molecules upon RNA hybridization. In this report we describe a chemical approach that leads to unprecedented bri...
Identification of an Exosomal miRNA Signature in Newly Diagnosed Essential Hypertensive Adults [0.03%]
新发原发性高血压成人外泌体miRNA标志物的识别
Paulina Pei Suu Tan,William M Chilian,Yook Chin Chia et al.
Paulina Pei Suu Tan et al.
Background: Hypertension is a major risk factor for cardiovascular diseases and premature death worldwide. Less than half of adults with hypertension are not properly diagnosed and treated indicating a need for better dia...
Fiona M Menzies
Fiona M Menzies
In the UK, there are approximately 650,000 babies born each year. The pregnancy journey is not only unique to each woman, but for each individual pregnancy that may be experienced. Pregnancy complications, miscarriage, and stillbirths are s...
Mesoporous Silica Microparticle Tablets for Optimised Formulation and Overcoming Compressibility Challenges [0.03%]
用于优化配方和克服压缩性难题的介孔 silica 微粒片剂
Mohamad Anas Al Tahan,Craig Russell,Ali Al-Khattawi
Mohamad Anas Al Tahan
Tablets are the most commonly used dosage form due to their low manufacturing cost and ease of administration. Incorporating mesoporous silica microparticles offers enhanced control over drug release and bioavailability; however, formulatio...
Reproducibility of Immunohistochemical Testing of Estrogen Receptors, Progesterone Receptors, Human Epidermal Growth Factor Receptor-2 (HER2) and Ki-67 in Vietnam [0.03%]
越南免疫组化检测雌激素受体、孕酮受体、人类表皮生长因子受体-2（HER2）和Ki-67的重复性研究
Thai Anh Tu,Nguyen Van Tin,Anthony Rhodes et al.
Thai Anh Tu et al.
Context: Immunohistochemical (IHC) testing of estrogen receptors (ER), progesterone receptors (PR), HER2 and Ki-67 on breast cancer samples is carried out in the majority of clinical departments to predict response to the...
Sorfina Binti Ahmad Hilmi,Dinesh Kumar Chellappan,Anil Philip Kunnath
Sorfina Binti Ahmad Hilmi
Non-malignant disorders of granulocytes and monocytes include a range of conditions characterized by either quantitative issues (such as cytopenias or cytophilias) or qualitative defects in innate immune cells. These disorders encompass neu...
Addressing Health Disparities: How Having a More Diverse Biomedical Workforce Can Contribute to Addressing Health Disparities in Communities that Are Often Underrepresented in the Healthcare System [0.03%]
解决健康差异问题：如何拥有更加多元的生物医学 workforce 来有助于弥补医疗系统中常常被忽视的社区中的健康差异问题
Victoria Heath,Claire L Price
Victoria Heath
Health disparities that are seen in underserved and underrepresented communities are a pressing issue in healthcare. These disparities are embedded into our society through structural inequalities that lead to poorer health outcomes in thos...
Rasha Abu-El-Ruz,Ali Hasan,Dima Hijazi et al.
Rasha Abu-El-Ruz et al.
Background: Artificial intelligence (AI) is increasingly playing important roles in healthcare diagnosis, treatment, monitoring, and prevention of diseases. Despite this widespread implementation of AI in biomedical scien...
A Systematic Review of Clinical Trials Using mRNA Vaccines for Infectious Diseases other than COVID-19 [0.03%]
mRNA疫苗非新冠肺炎适应症临床试验的系统综述
Athina Sofroniou,Anna Ridley
Athina Sofroniou
Background: Although mRNA-based vaccines have been in development for over two decades, their widespread use only emerged during the COVID-19 pandemic. The success of these vaccines has brought mRNA technology to the fore...
The Growing Demand for Peer Review: Current Challenges and Potential Reforms [0.03%]
peer review需求的增长：当前挑战与潜在改革
Pierpaolo Pellicori,Jonathan Douxfils,Robert J Mentz et al.
Pierpaolo Pellicori et al.