Age-Related Loss of GPR68 and Calretinin Immunoreactive Neurons Within the Mucosa, Not the Myenteric Plexus of Human Colon [0.03%]
Nicholas Baidoo,Enrica De Rasis,Luke Paine et al.
Nicholas Baidoo et al.
Background: The G protein-coupled receptor 68 (GPR68) detects variations in extracellular pH, and has potential roles in homeostasis and responses to ischaemia and inflammation within different organs, including the gastr...
Challenges in Diagnosis of Lepidic Subtype in Lung Cancer According to W.H.O Classification: A Case Report [0.03%]
肺癌WHO分类中肺 lepidic 组织学亚型诊断面临的挑战：一例报告
Cuong Pham Nguyen,Long Thien Phan,Phuong Thi Phan et al.
Cuong Pham Nguyen et al.
Background: Lepidic adenocarcinoma of the lung often presents with atypical radiological patterns mimicking pneumonia, posing significant diagnostic challenges, particularly from small cytology samples. This can lead to d...
Carbon Quantum Dots as Versatile Nanosystems for Biomedical Innovation: Mechanisms, Applications, and Translational Prospects [0.03%]
用于生物医学创新的碳量子点多功能纳米系统：机制、应用和转化前景
Jasdev Singh Maan,Milind Kuruvath Santhosh,Stevelyn Jia Xin Lee et al.
Jasdev Singh Maan et al.
Carbon quantum dots (CQDs) represent a rapidly developing class of fluorescent nanomaterials with increasing relevance in biomedical research and application. Their tuneable photoluminescence (PL), favourable biocompatibility, and versatile...
High-Fat Diet Anticipates Age-Related Sarcopenia Through Increased Oxidative Stress and Inflammation [0.03%]
高脂肪饮食通过增加氧化应激和炎症来预示年龄相关的肌肉减少症
Fabiano Cimmino,Lidia Petrella,Gina Cavaliere et al.
Fabiano Cimmino et al.
Background: Ageing, a physiological process, and obesity, a pathological condition, are both associated with several metabolic alterations including energy imbalance, altered body composition, chronic low-grade inflammati...
Breast Cancer Disparities in African and African-Ancestry Populations: Genetics, Epigenetics, Structural Barriers and Technology-Enabled Solutions [0.03%]
非洲和非裔血统人群中的乳腺癌差异：遗传、表观遗传学、结构障碍及技术赋能解决方案
Chika Eze,Rasha Swadi,Kehinde Ross et al.
Chika Eze et al.
Breast cancer remains a leading cause of mortality among women globally, with disproportionately high incidence, aggressive subtypes and poor outcomes in African and African-ancestry populations. While inherited BRCA1/BRCA2 mutations drive ...
Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics [0.03%]
替代聚腺苷酸化标志物可区分肺动脉高压的不适应性右心室重塑：RNA诊断和治疗的启示
Janani Subramaniam,Venkata Jonnakuti,Scott D Collum et al.
Janani Subramaniam et al.
Increased pulmonary vascular pressures due to vascular remodeling, elevated vascular resistance, and vasoconstriction characterize Pulmonary Arterial Hypertension (PAH). The narrowing of the pulmonary arteries and obstruction of blood flow ...
An Analysis of the Career Pathway of Clinical Laboratory Scientists: Identifying Access Barriers and Best Practice to Increase Diversity in the Workforce [0.03%]
临床实验室科学家职业路径分析：识别进入壁垒及增加劳动力多样性的最佳实践探讨
James A O&#x;Connor
James A O&#x;Connor
Widening participation among the clinical laboratory scientific workforce is essential to meet future needs of healthcare systems. The advantages of more diversity in this clinically pivotal workforce include better decision making, improve...
Assessing the Impact of Mesoporous, Co-Amorphous, and Polymer-Based Systems on Cefdinir's Dissolution and Stability Via Predictive Modeling [0.03%]
通过预测建模评估介孔、共无定形和聚合物系统对头孢地尼溶出度和稳定性的影响
Raghad Al Nuss,Mohamad Anas Al Tahan,Hind El-Zein
Raghad Al Nuss
The poor solubility and permeability of Biopharmaceutics Classification System (BCS) Class IV drugs pose major challenges to achieving sufficient oral bioavailability and therapeutic efficacy. Improving drug dissolution is a key strategy to...
Beverley C Millar,Mary J Cates,Marco S Torrisi et al.
Beverley C Millar et al.
Antimicrobial resistance (AMR) has caused a global public health crisis, contributing to approximately five million deaths in 2019 and predicted deaths of approximately ten million annually by 2050. This equates to approximately 1.4-fold mo...
Investigating the Barriers Faced by Biomedical Science Undergraduates in Completing a Placement Year [0.03%]
探究生物医学科学本科生完成实习年所面临的障碍
Kathryn Dudley,Amreen Bashir
Kathryn Dudley
Introduction: Research shows completing a placement year is associated with improved academic and employment outcomes. For Biomedical science courses, pathology placements allow completion of the Institute of Biomedical S...