Longitudinal agreement of repeated critical haemoglobin measurements as evidence of sustained analytical quality [0.03%]
重复测定关键血红蛋白测量值的一致性作为持续性分析质量的证据
Vanda Simões,Cacilda Magalhães,Yuliana O Eremina
Vanda Simões
Pleiotropic effects of GDF-15 to regulate nutritional status: perspectives from body composition to nutrition-related disorders [0.03%]
GDF-15的多效性作用调节营养状态：从身体成分到与营养相关的疾病的角度透视
Binbin Peng,Wei Zhao,Ming Kong et al.
Binbin Peng et al.
Growth differentiation factor 15 (GDF-15), a stressful cytokine of the transforming growth factor-β (TGF-β) superfamily, plays pivotal roles in diverse physiological and pathological processes. Most recently, its pleiotropic effects regar...
Immunohistochemical testing of GISTs using CD117 markers: the UK NEQAS ICC & ISH external quality assessment data show significant differences in the performance of methods in regular use [0.03%]
CD117染色滤纸干血斑检测胃肠道间质瘤的英国NEQAS免疫组化和原位杂交外部质量评估数据
Andrew Dodson,Suzanne Parry
Andrew Dodson
Background: CD117 (c-KIT) is a tyrosine kinase receptor protein, mutations in which are important in the tumourigenesis of gastrointestinal stromal tumour (GIST). Immunohistochemical detection of CD117 is the primary iden...
Concordance between crude extract and component allergens in a multiple allergen simultaneous test: a large-scale retrospective analysis [0.03%]
一种同时型多过敏原检测中粗提取物与成分特异性过敏原的一致性分析：一项大规模回顾性研究
Hyejin Ryu,Kuenyoul Park,Kina Kim et al.
Hyejin Ryu et al.
Objectives: Multiple allergen simultaneous tests (MAST) increasingly incorporate both crude extract and molecular component allergens for specific IgE testing. However, systematic data on the diagnostic concordance betwee...
Evaluation of analytical performance of the Revvity sFlt-1 and PlGF methods for the assessment of preeclampsia [0.03%]
评估Revitity公司sFlt-1和PlGF方法在子痫前期评估中的分析性能
Rhiannon Marr,Ana Sofia Cerdeira,Ian Smith et al.
Rhiannon Marr et al.
Introduction: The measurement of the angiogenic biomarkers placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) are increasingly used to support the prediction and diagnosis of preeclampsia (PE) ...
Supporting quantitative skills in biomedical science with smart worksheets: intentions, impact and barriers to engagement [0.03%]
具有智能工作表的生物医学科学定量技能支持：参与意愿、影响和障碍
Leanne Williams,Emily Coyte,Sue Jones et al.
Leanne Williams et al.
Introduction: The growing diversity of university student populations highlights the critical need for inclusive support strategies. Student outcomes often remain linked to socio-economic factors and Level 3 qualification...
Artificial intelligence approaches in biological age prediction: current status and challenges [0.03%]
人工智能在生物年龄预测中的应用：现状与挑战
Guangjun Wang,Pengcheng Ding,Zihui Li et al.
Guangjun Wang et al.
Biological age (BA) prediction has emerged as a critical research frontier for evaluating individual health status and aging trajectories beyond chronological age (CA). Recent advances in artificial intelligence (AI) have substantially acce...
Challenges and emerging strategies for genome-wide evaluation of loss of imprinting in cancer [0.03%]
癌症中全基因组印迹丢失评价的挑战及新策略
Muhammad Talal Amin,Louis Coussement,Tim De Meyer
Muhammad Talal Amin
Genomic imprinting is the phenomenon in which only a single allele of a gene is expressed based on its parental origin, thereby deviating from the typical biallelic expression of autosomal genes. It is meticulously controlled by epigenetic ...
Application of non-invasive preimplantation genetic screening for aneuploidy through spent embryo culture media analysis at 48 and 54 hours after embryo cleavage [0.03%]
胚胎卵裂后48和54小时利用废弃的培养液进行非侵入性筛查的应用研究
Chonthicha Satirapod,Pornsri Niransuk,Siriluk Tantanavipas et al.
Chonthicha Satirapod et al.
Background: This study aims to assess the effectiveness of non-invasive preimplantation genetic testing (niPGT) for detecting aneuploidy at two different time points, 48- and 54-hour following the cleavage stage of embryo...
Training on PD-L1 scoring in non-small cell lung cancer with high intra- and inter-reader agreement: results of a worldwide microscopic/digital image-based training of 751 pathologists [0.03%]
基于PD-L1评分的非小细胞肺癌高可读性和交互阅读协议培训：来自全球微观/数字图像的751位病理学家的结果
Gudrun Bänfer,Rolf Diezko,Rabea Oberthür et al.
Gudrun Bänfer et al.
Semi-quantitative scoring of PD-L1 expression on tumor cells (TCs) and/or infiltrating immune cells (ICs) is complex and requires expert pathologist training to reduce inter- and intra-reader variability. We conducted a 1- or 2-day training...