Heparan sulfate as a central modulator of growth factor dynamics in tissue regeneration [0.03%]
肝糖胺聚糖在组织再生中作为生长因子动态变化的中央调节者
Keyu Tao,Ali Shokoohmand,Simon M Cool et al.
Keyu Tao et al.
Growth factors (GFs) are potent regenerative proteins that modulate biological responses and stimulate tissue repair by activating cell signaling pathways to enhance proliferation, differentiation, and migration. However, the rapid degradat...
ALK5 inhibitor impact on bleomycin-induced systemic sclerosis mouse model via multifunctional optical coherence tomography [0.03%]
多功能光学相干断层扫描观察ALK5抑制剂对博来霉素诱导的大鼠系统性硬化症的影响
Pavel V Nikitin,Harshdeep S Chawla,Jessica Gutierrez et al.
Pavel V Nikitin et al.
Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by fibrosis, vascular dysfunction, and immune dysregulation, leading to significant morbidity and mortality. Noninvasive imaging techniques are critical for monitoring d...
Digital light processing of hydrogel molds to guide cell mechanosensing and the fabrication of meniscal tissue constructs [0.03%]
用于引导细胞机械传导和制造半月板组织构建体的水凝胶模具的数字光处理技术
Alysse DeFoe,Joshua Toth,Abhishek P Dhand et al.
Alysse DeFoe et al.
The organization of cells and extracellular matrix (ECM) informs tissue function. This structure/function relationship is especially evident in musculoskeletal (MSK) tissues in which a specific ECM organization (e.g., anisotropy) guides dir...
Synergy between photonics and biological approaches-A review of combination therapies for cancer theranostics [0.03%]
光子学和生物方法之间的协同作用-癌症诊疗的组合疗法综述
Jacob P Adams,Luke Pauli,Lin Wang et al.
Jacob P Adams et al.
Cancer therapies have evolved considerably over the past several decades. Physical interactions, particularly through phototherapy as a new class of treatment modality, have become widely used. Phototherapy utilizes light to combat cancer b...
Yuchen Song,Shuang Wei,Haibin Zou et al.
Yuchen Song et al.
Photo-sono therapy (PST) is a cavitation-based anti-vascular and thrombolysis treatment strategy. Compared to conventional high intensity focused ultrasound treatment, PST can selectively treat blood vessels and clots because of optical abs...
Oligonucleotide surface attachment by tosylation for digital detection of microRNA using photonic resonator absorption microscopy [0.03%]
基于托磺化法的寡核苷酸表面固定用于光子共振吸收显微镜数字化检测microRNA
Skye Shepherd,Joseph Tibbs,Seemesh Bhaskar et al.
Skye Shepherd et al.
DNA capture probes attached to surfaces are necessary for many biosensing assays for the specific detection of nucleic acid target sequences. In this work, we present a chemically mediated direct oligonucleotide-titanium dioxide bond for st...
Subject-specific multivariate modeling for regenerative rehabilitation of bone healing [0.03%]
用于骨愈合再生康复的学科特定多元模型
Kylie E Williams,Farhan Muhib,Ethan Dinh et al.
Kylie E Williams et al.
Rehabilitation can help promote functional restoration following surgical reconstruction of severe bone injuries, yet prescribed regimens are often conservative due to limited understanding of their impact on healing. This study examined ro...
Assessing human scalp and brain blood flow sensitivities via superficial temporal artery occlusion using speckle contrast optical spectroscopy [0.03%]
基于光学speckle对比光谱的颞浅动脉阻断法评估头皮和脑部血流量的敏感性
Yu Xi Huang,Simon Mahler,Maya Dickson et al.
Yu Xi Huang et al.
Cerebral blood flow is a critical metric for cerebrovascular monitoring, with applications in stroke detection, brain injury evaluation, aging, and neurological disorders. Noninvasively measuring cerebral blood dynamics is challenging due t...
Skin-on-chip: Quo vadis? [0.03%]
皮肤芯片：路在何方？
Mina Ghiță-Răileanu,Bianca-Maria Tihăuan,Irina-Oana Lixandru-Petre et al.
Mina Ghiță-Răileanu et al.
There is a need for reconstructing the structural and functional complexity of human tissues such as skin to replace the animal models and provide accurate knowledge while solving ethical challenges in human medicine. Lately, microfluidics ...
Low-intensity pulsed ultrasound alleviates periodontitis in mice with T2DM through Nrf2 pathway [0.03%]
低强度脉冲超声通过Nrf2途径缓解T2DM小鼠的牙周炎
Yiyao Hu,Yunchun Kuang,Houxuan Li et al.
Yiyao Hu et al.
Periodontitis is a prevailing disease and a leading contributor to dentition defects in adults. Regeneration of soft tissue and alveolar bone is further limited in periodontitis with type 2 diabetes mellitus (T2DM). Low-intensity pulsed ult...