Predictive simulation of coil mechanics uncovers shape-driven determinants of endovascular coiling efficacy in intracranial aneurysms [0.03%]
预测线圈力学的模拟揭示了颅内动脉瘤血管内线圈栓塞有效性的形状决定因素
Dario Tarantino,Alessandra Corvo,Chiara Livolsi et al.
Dario Tarantino et al.
Endovascular coiling is a minimally invasive therapeutic option for intracranial aneurysm (IA). This technique involves occluding the aneurysmal sac with one or more metallic coils to decrease perfusion of the dilated arterial wall. Althoug...
Prediction of arrhythmogenesis in non-ischemic cardiac resynchronization therapy patients [0.03%]
非缺血性心脏再同步治疗患者室性心律失常发生的预测模型研究
Alessandra Corda,Massimiliano Maines,Stefano Pagani et al.
Alessandra Corda et al.
We aim to develop a patient-specific computational model to predict the risk of Ventricular Tachycardia (VT) in patients with a Biventricular Cardiac Resynchronization Therapy (BiV-CRT) device. Patients are indeed at risk of developing arrh...
Structural and functional benchmarking of monolayer- and bioreactor-generated hiPSC-derived cardiomyocytes [0.03%]
基于单层和生物反应器的人类诱导多能干细胞源性心肌细胞的结构和功能标准化考核评价体系
Yongjun Jang,Kevin Shani,Anna Clouvel-Gervaiseau et al.
Yongjun Jang et al.
Transitioning from animal to human cell sources represents a critical milestone in cardiac tissue engineering and biomedical research. Neonatal rat ventricular myocytes (NRVMs) have long served as the functional benchmark for engineered car...
MRI-guided endovascular robotics: A roadmap to MRI-native systems [0.03%]
磁共振引导的血管机器人技术：迈向原生磁共振系统的路线图
Giulio Dagnino
Giulio Dagnino
Magnetic resonance imaging (MRI) offers potential advantages for endovascular intervention, including excellent soft-tissue contrast, multi-planar visualization, and the possibility of radiation-free guidance. Emerging robotic platforms, MR...
Shape factor analysis as a quantitative framework for assessing spheroid and organoid morphology and invasiveness [0.03%]
形态因子分析作为评估类器官形态和侵袭性的定量框架
Brittany E Schutrum,Jenny Deng,Ju Hee Kim et al.
Brittany E Schutrum et al.
Morphological changes in spheroids and organoids are widely used as in vitro indicators of healthy and diseased tissue function, but selecting appropriate methods to quantify these changes remains challenging. Shape factors (or shape descri...
HB-EGF enhances collective cell migration via spatial coordination of traction [0.03%]
HB-EGF通过牵引力的时空协调促进集体细胞迁移
Jonah J Spencer,Emily Rhine,Pamela K Kreeger et al.
Jonah J Spencer et al.
An important process in wound healing is re-epithelialization, wherein cells collectively migrate to cover the wounded area. Here, we investigate how cellular forces lead to the migration of an epithelial monolayer in a wound healing assay....
A pump-free microfluidic device for integrated multi-functional testing of tumor spheroids [0.03%]
一种用于肿瘤球形体集成多功能测试的无泵控微流体装置
Eliana Steinberg,Gabriel D Azulay,Alina Ruiz de Villa et al.
Eliana Steinberg et al.
Three-dimensional (3D) multicellular ex vivo cultures have become central tools for cancer research and drug testing under physiologically relevant conditions. Organ-on-a-chip technologies based on microfluidics provide platforms for cultur...
Photobiomodulation outperforms ultrasound in reducing IL-1 β -driven chondrocyte inflammation [0.03%]
光生物调节优于超声波可减少IL-1β引起的软骨细胞炎症
Sofia Oliveira,Débora Ferreira,Ligia R Rodrigues et al.
Sofia Oliveira et al.
Therapeutic ultrasound (US) and photobiomodulation (PBM) are promising treatment modalities for restoring articular cartilage. Owing to their different mechanisms of action, individual or combined stimulation may elicit different bioeffects...
Research progress of 3D-printed anti-infective bone tissue engineering scaffolds based on triply periodic minimal surface structures [0.03%]
基于三重周期极小曲面结构的3D打印抗感染骨组织工程支架研究进展
Peijie Zhao,Yafeng Zhang,Zewen Qiao
Peijie Zhao
Bone defect repair remains a significant clinical challenge, necessitating scaffold materials that combine excellent mechanical properties, bioactivity, and anti-infective capabilities, which are central to bone tissue engineering. Triply p...
Biomolecular and cellular chirality: Novel diagnostic perspectives for diseases [0.03%]
生物分子及细胞的手性特性：疾病诊断的新视角
Xinwei Guo,Yi Zheng,Weifang Zhang et al.
Xinwei Guo et al.
Chirality is an intrinsic characteristic of living systems, manifesting as a pervasive asymmetry from the molecular to the cellular level. This asymmetry regulates normal life activities through precise stereospecific recognition between mo...