Volume-amplified magnetic bioassay integrated with microfluidic sample handling and high- Tc SQUID magnetic readout [0.03%]
集成有微流控样品处理和高温SQUID磁场读出的体积放大的磁生物测定法
Sobhan Sepehri,Emil Eriksson,Alexei Kalaboukhov et al.
Sobhan Sepehri et al.
A bioassay based on a high-Tc superconducting quantum interference device (SQUID) reading out functionalized magnetic nanoparticles (fMNPs) in a prototype microfluidic platform is presented. The target molecule recognition is based on volum...
Synthesis and targeting of gold-coated 177Lu-containing lanthanide phosphate nanoparticles-A potential theranostic agent for pulmonary metastatic disease [0.03%]
一种潜在的肺转移疾病诊疗剂——金包覆含177Lu镧系磷酸盐纳米颗粒的合成与靶向研究
Nicholas Sobol,Logan Sutherlin,Edyta Cedrowska et al.
Nicholas Sobol et al.
Targeted radiotherapies maximize cytotoxicity to cancer cells. In this work, we describe the synthesis, characterization, and biodistribution of antibody conjugated gold-coated lanthanide phosphate nanoparticles containing 177Lu. [177Lu]Lu0...
Federica Rigoldi,Stefano Donini,Alberto Redaelli et al.
Federica Rigoldi et al.
The catalytic properties of some selected enzymes have long been exploited to carry out efficient and cost-effective bioconversions in a multitude of research and industrial sectors, such as food, health, cosmetics, agriculture, chemistry, ...
Geometric confinement is required for recovery and maintenance of chondrocyte phenotype in alginate [0.03%]
透明质酸中软骨细胞表型的恢复和维持需要几何约束条件
Megan E Cooke,Mark J Pearson,Richard J A Moakes et al.
Megan E Cooke et al.
Human articular chondrocytes lose their native phenotype when expanded in traditional monolayer cultures. As a consequence, hydrogel encapsulation has been investigated as a means to maintain the natural phenotype. Alginate has been widely ...
Tanmay Ghonge,Anurup Ganguli,Enrique Valera et al.
Tanmay Ghonge et al.
Antigen expression is an important biomarker for cell analysis and disease diagnosis. Traditionally, antigen expression is measured using a flow cytometer which, due to its cost and labor intensive sample preparation, is unsuitable to be us...
Flexible and disposable paper- and plastic-based gel micropads for nematode handling, imaging, and chemical testing [0.03%]
用于线虫处理、成像和化学检测的柔性纸基凝胶微垫及其塑料版本一次性用品
Zach Njus,Taejoon Kong,Upender Kalwa et al.
Zach Njus et al.
Today, the area of point-of-care diagnostics is synonymous with paper microfluidics where cheap, disposable, and on-the-spot detection toolkits are being developed for a variety of chemical tests. In this work, we present a novel applicatio...
An evaluation of irreversible electroporation thresholds in human prostate cancer and potential correlations to physiological measurements [0.03%]
人前列腺癌不可逆电穿孔阈值的评估及其与生理测量潜在相关性的研究
Sabrina Campelo,Massimo Valerio,Hashim U Ahmed et al.
Sabrina Campelo et al.
Irreversible electroporation (IRE) is an emerging cancer treatment that utilizes non-thermal electric pulses for tumor ablation. The pulses are delivered through minimally invasive needle electrodes inserted into the target tissue and lead ...
Justin Cooper-White
Justin Cooper-White
The Extracellular Matrix of Ovarian Cortical Inclusion Cysts Modulates Invasion of Fallopian Tube Epithelial Cells [0.03%]
卵巢皮质包涵囊肿的细胞外基质调节输卵管上皮细胞侵袭作用
Andrew J Fleszar,Alyssa Walker,Veronica Porubsky et al.
Andrew J Fleszar et al.
A growing body of research supports the idea that the fallopian tube epithelium (FTE) is the precursor for most high-grade serous ovarian canacers (HGSOC) but that the ovary plays a critical role in tumor metastasis. Cortical inclusion cyst...
MRI analysis to map interstitial flow in the brain tumor microenvironment [0.03%]
利用MRI分析绘制脑肿瘤微环境内流体流动分布图
Kathryn M Kingsmore,Andrea Vaccari,Daniel Abler et al.
Kathryn M Kingsmore et al.
Glioblastoma (GBM), a highly aggressive form of brain tumor, is a disease marked by extensive invasion into the surrounding brain. Interstitial fluid flow (IFF), or the movement of fluid within the spaces between cells, has been linked to i...