Diffraction-informed deep learning for molecular-specific holograms of breast cancer cells [0.03%]
用于乳腺癌细胞分子特异性全息图的衍射辅助深度学习
Tzu-Hsi Song,Mengzhi Cao,Jouha Min et al.
Tzu-Hsi Song et al.
Lens-free digital in-line holography (LDIH) provides a large field-of-view at micrometer-scale resolution, making it a promising tool for high-throughput cellular analysis. However, the complexity of diffraction images (holograms) produced ...
Continuous noninvasive blood pressure estimation using tissue blood flow measured by diffuse correlation spectroscopy [0.03%]
基于扩散相关光谱组织血流测量的连续无创血压估计技术
Zhe Li,Jiangtao Bai,Xiangyu Cao et al.
Zhe Li et al.
Blood pressure (BP) is an important parameter of human health, since hypertension is a major risk factor of the cardiovascular system. Nowadays, the continuous measurement of BP is only possible with an invasive measurement method using cat...
Regulation of airway remodeling in asthma: The synergistic effects of nanotechnology and Hippo pathway activation [0.03%]
哮喘气道重塑的调控：纳米技术与Hippo信号通路活化的协同作用
Zhihua Li,Mingrui Yan,Jiaqi Bi et al.
Zhihua Li et al.
Asthma is a prevalent chronic respiratory condition characterized by airway remodeling, which contributes to irreversible airway narrowing and impaired lung function. Current therapies fail to effectively address this structural alteration....
Mohsen Taghizadeh,Ali Taghizadeh,Hye Sung Kim
Mohsen Taghizadeh
Organoid culture systems have emerged as powerful platforms for studying development, disease modeling, and regenerative medicine. However, current models primarily rely on spontaneous self-organization within biomimetic matrices such as Ma...
Microwave-assisted immunostaining for rapid labeling of matrix-embedded multicellular structures [0.03%]
微波辅助免疫染色法：快速标记基质中包埋的多细胞结构的一种新方法
Kevin J Schilling,Katherine T Huynh,Sean Speese et al.
Kevin J Schilling et al.
Immunofluorescence staining of cell proteins is essential to understanding biomolecular interactions within three-dimensional (3D) hydrogel cell cultures. However, the scaffold material limits passive diffusion of antibodies through thick 3...
Jielong Yang,Jing Yang,Tianye Niu et al.
Jielong Yang et al.
Radiomics methods are essential in cancer image analysis due to their excellent ability in extracting quantitative imaging features. Existing radiomics methods adopt either statistical models for data preprocessing and feature engineering o...
Peptide coacervates as intracellular delivery vehicles for synergistic cancer photothermal- and chemo-therapies [0.03%]
用于协同癌症光热和化疗的肽共聚物intracellular递送载体
Congxi Huang,Sushanth Gudlur,Syed Maricar et al.
Congxi Huang et al.
Intracellular delivery of large molecular weight therapeutics poses a significant challenge in targeted cancer therapy, as conventional delivery vehicles often fail to achieve efficient cellular uptake and controlled release. This study pre...
Frequency and duration of sensory flicker control transcriptional profiles in 5xFAD mice [0.03%]
5XFAD小鼠中感觉闪烁控制转录谱的频率和持续时间
Sara Bitarafan,Alyssa F Pybus,Felix G Rivera Moctezuma et al.
Sara Bitarafan et al.
Current clinical trials are investigating gamma frequency sensory stimulation as a potential therapeutic strategy for Alzheimer's disease (AD); yet, we lack a comprehensive picture of the effects of this stimulation on multiple aspects of b...
TTLL4 mediates the PI3K/AKT/MDM2 pathway to promote hepatocellular carcinoma progression and predict patient prognosis [0.03%]
TTLL4通过介导PI3K/AKT/MDM2信号通路促进肝癌进展并预测患者预后
Zeping He,Desheng Chen,Lei Li et al.
Zeping He et al.
Hepatocellular carcinoma (HCC) is a highly lethal and heterogeneous tumor driven by the dysregulation of multiple genes. Tubulin tyrosine ligase-like 4 (TTLL4) has been linked to tumor progression, but its specific role in HCC pathogenesis ...
Claudia Fischbach,Corey S O&#x;Hern,Adam J Engler
Claudia Fischbach