Platelet membrane-coated nanoparticles: Bioengineering principles, quality control, and translational opportunities [0.03%]
基于血小板膜的纳米药物递送系统:生物工程原理、质量控制及转化机遇
Ncobile Bagezile Mdlovu,Liling Delila,Si-Han Wu et al.
Ncobile Bagezile Mdlovu et al.
Platelet membranes (PMs) are increasingly explored as bioinspired coatings for nanoparticles (NPs), providing improved immune evasion, prolonged circulation, and disease-homing properties that enhance targeted drug delivery. Unlike conventi...
Flow molecular dynamics simulations reveal mechano-presentation of von Willebrand factor through glycan-modulated autoinhibitory modules [0.03%]
流体分子动力学模拟揭示糖基修饰的自动抑制模块调控von Willebrand因子的力呈现机制
Naveen Eugene Louis Richard Louis,Yunduo Charles Zhao,Lining Arnold Ju
Naveen Eugene Louis Richard Louis
Force-induced protein conformational changes govern many essential biological processes, yet their molecular mechanisms remain difficult to resolve. Von Willebrand factor (VWF), a central regulator of hemostasis, is activated by hydrodynami...
A wireless and handheld optical palpation imaging probe for use in breast-conserving surgery [0.03%]
一种用于保乳手术的无线手持式光学触觉成像探针
Rhys Jones,Renate Zilkens,Ankit Bharakhda et al.
Rhys Jones et al.
We present a wireless and handheld optical elastography probe aimed toward improving intraoperative discrimination between malignant and benign tissue in breast-conserving surgery. If successful, this probe can contribute to reducing close ...
Force-sensing mobile microrobotic grippers for gentle and precise bioassembly of cell spheroids [0.03%]
用于细胞球体温和而精确生物装配的力觉传感型手机微机器人机械手
Aaron C Davis,Madison OBrien,Iris Gong et al.
Aaron C Davis et al.
This paper presents a wireless mobile microrobot gripper for the pick-and-place bioassembly of cell spheroids, which are crucial for tissue engineering. To address the risk of cellular damage during handling, this technology integrates real...
Erratum: "Credibility assessment of patient-specific modeling in transcatheter aortic valve implantation. I. A population-based validation of patient-specific modeling" [APL Bioeng. 9, 046101 (2025)] [0.03%]
勘误:「经导管主动脉瓣植入物的个性化建模可信度评估。I. 基于人群的个性化建模验证」[APL Bioeng. 9, 046101 (2025)]
Chiara Catalano,Roberta Scuoppo,Tahir Turgut et al.
Chiara Catalano et al.
[This corrects the article DOI: 10.1063/5.0280958.]. © 2026 Author(s).
Published Erratum
APL bioengineering. 2026 Apr 22;10(2):029901. DOI:10.1063/5.0335660 2026
Erratum: "Credibility assessment of patient-specific modeling in transcatheter aortic valve implantation-Part 2: Uncertainty quantification and sensitivity analysis" [APL Bioeng. 9, 046102 (2025)] [0.03%]
勘误:「经导管主动脉瓣植入的患者特定建模可信度评估——第2部分:不确定性量化与敏感性分析」[APL Bioeng. 9, 046102 (2025)]
Roberta Scuoppo,Chiara Catalano,Tahir Turgut et al.
Roberta Scuoppo et al.
[This corrects the article DOI: 10.1063/5.0280959.]. © 2026 Author(s).
Published Erratum
APL bioengineering. 2026 Apr 22;10(2):029902. DOI:10.1063/5.0335662 2026
Research progress in flap temperature monitoring technologies and applications after transplantation [0.03%]
移植术后皮瓣温度监测技术及应用研究进展
Tingting Hu,Tao Yan,Junjie Chen et al.
Tingting Hu et al.
As a primary method for tissue repair and functional reconstruction, flap transplantation has achieved a clinical success rate of over 90%. However, the postoperative incidence of vascular crisis remains as high as 10%-30%, making it a lead...
Mapping the miRNA landscape of primitive macrophage extracellular vesicles highlights their pro-vasculogenic effects in engineered human cardiac tissue [0.03%]
原代巨噬细胞外泌体的miRNA图谱分析揭示其在工程化人心肌组织中的促血管生成作用
Karl T Wagner,Shira Landau,Gregory M Kent et al.
Karl T Wagner et al.
Resident cardiac macrophages, derived from primitive yolk sac precursors during embryogenesis, have increasingly been recognized for their distinct phenotype and functions in regulating homeostasis of the human heart. However, the profile o...
Research advances in intelligent microenvironment-responsive hydrogels for myocardial infarction therapy [0.03%]
智能微环境响应水凝胶促进心肌梗死治疗研究进展
Jian Li,Jinglin Gao,Kaiyi Zhu et al.
Jian Li et al.
Myocardial infarction (MI) poses a severe threat to human life and health. During acute MI, persistent myocardial ischemia and hypoxia induce pathological alterations in the microenvironment. Traditional therapeutic approaches exhibit limit...
Na Yeon Kim,Hyojung Jo,Chloe Becker et al.
Na Yeon Kim et al.
Mechanical cues control key aspects of cardiac structure formation and function from heart development through adult life. Because the heart is a pump, forces from muscle contraction and blood flow generate normal and shear stresses that, t...