When in vitro is not enough: In silico strategies to investigate functional and dynamical properties of large-scale neuronal assemblies [0.03%]
体外不够用时:用于研究大规模神经元联合的功能和动力学特性的计算机策略
Francesca Callegari,Rachele Fabbri,Valerio Barabino et al.
Francesca Callegari et al.
Understanding how neuronal circuits generate complex activity patterns and perform computations remains a significant challenge in neuroscience. In vitro neuronal models provide controlled environments to investigate brain microcircuits, th...
Finger joint angle and gesture estimation under natural conditions with a soft printed electrode array [0.03%]
基于软印刷电极阵列的自然条件下手指关节角度及手势估计
Nitzan Luxembourg,Rufael Fekadu Marew,Dvir Teitelbaum et al.
Nitzan Luxembourg et al.
Innovative methods for finger gesture recognition have been an active research area, with surface electromyography (sEMG) emerging as a promising approach in human-machine interface applications, especially when visual imaging is impractica...
EndoSCell: A portable intraoperative histopathological microscopy device for enhanced glioma resection and prognosis in animal models [0.03%]
内窥镜细胞学:一种便携式术中组织病理显微镜设备,可增强动物模型中的胶质瘤切除和预后
Yu-Chien Lin,Ke-Jun He,Ming-Yang Jiang et al.
Yu-Chien Lin et al.
Safe maximal resection remains a critical goal and prognostic factor in glioma treatment. Neurosurgeons face significant challenges in accurately identifying the true extent of glioma during surgery due to its highly infiltrative nature. Cu...
Credibility assessment of patient-specific modeling in transcatheter aortic valve implantation-Part 2: Uncertainty quantification and sensitivity analysis [0.03%]
经导管主动脉瓣植入术中基于患者的建模可信度评估-第2部分:不确定性分析及敏感性分析
Roberta Scuoppo,Chiara Catalano,Tahir Turgut et al.
Roberta Scuoppo et al.
Transcatheter aortic valve implantation (TAVI) benefits from patient-specific computational modeling, yet model credibility remains a challenge. The ASME V&V40 standard provides a framework for assessing uncertainty and sensitivity in in si...
Credibility assessment of patient-specific modeling in transcatheter aortic valve implantation. I. A population-based validation of patient-specific modeling [0.03%]
经导管主动脉瓣植入的个性化模拟的可信度评估Ⅰ基于人群的个性化建模验证研究
Chiara Catalano,Roberta Scuoppo,Tahir Turgut et al.
Chiara Catalano et al.
Transcatheter aortic valve implantation (TAVI) has become a standardized treatment for aortic valve stenosis, supported by computational modeling to enhance procedural planning. However, the credibility of TAVI simulations requires rigorous...
Machine learning-enabled detection of electrophysiological signatures in iPSC-derived models of schizophrenia and bipolar disorder [0.03%]
基于诱导多能干细胞的精神分裂症和双相情感障碍模型的机器学习电生理特征检测方法研究
Kai Cheng,Autumn Williams,Anannya Kshirsagar et al.
Kai Cheng et al.
Neuropsychiatric disorders such as schizophrenia (SCZ) and bipolar disorder (BPD) remain challenging to diagnose due to the absence of objective biomarkers, with current assessments relying largely on subjective clinical evaluations. In thi...
A comprehensive review of graphene-based biosensors: Fabrication, applications, characterization and future perspectives-A review [0.03%]
基于石墨烯的生物传感器综合评论:制备、应用、表征和未来展望-综述文章
Yao-Tung Wang,Arvind Mukundan,Riya Karmakar et al.
Yao-Tung Wang et al.
Graphene is a 2D material that has emerged as a versatile and advanced material for biosensing technology due to its large surface area, high conductivity, and biocompatibility. These properties make it well-suited for label-free detection ...
The glioblastoma biomechanical landscape: A systematic review of magnetic resonance elastography (MRE) of brain tumors and healthy brain [0.03%]
磁共振弹性成像(MRE)技术在脑肿瘤和健康大脑中的系统性综述:胶质母细胞瘤生物力学景观的研究进展
Thuvarahan Jegathees,Lauriane Jugé,Eric Hau et al.
Thuvarahan Jegathees et al.
Diagnosis of a glioblastoma (GBM) brain tumor is associated with very poor prognosis. Currently, few preclinical models used to identify new therapies address the soft brain tissue environment and GBM mechanoresponses, which are implicated ...
3D bioprinted human iPSC-derived neural progenitor cells as a novel platform for studying neurogenic niche [0.03%]
基于人多能干细胞的3D生物打印神经前体细胞作为研究神经生成生态位的新平台
Lucas Simões Machado,Paula Scanavez Ferreira,Marina Rodrigues Pires et al.
Lucas Simões Machado et al.
Animal models, especially rodents, used to study neurodevelopment have significantly advanced our comprehension of cellular and molecular mechanisms. Nevertheless, differences in species-specific structures, gestation periods, and interneur...
Integrated microfluidic platforms for extracellular vesicles: Separation, detection, and clinical translation [0.03%]
集成微流控平台用于外泌体:分离、检测和临床转化
Yang Dai,Yibo Cui,Jinwen Li et al.
Yang Dai et al.
Extracellular vesicles (EVs), secreted by most living cells, encapsulate a diverse array of bioactive molecules from their parent cells, including proteins and nucleic acids. Recent studies underscore the potential of EVs as advanced biomar...