AI-guided computational design of synthetic microbiota for next-generation immunomodulatory applications [0.03%]
基于人工智能的合成式微生物组下一代免疫调节应用的计算设计
Awadh Alanazi,Mohamed N Ibrahim,Bi Bi Zainab Mazhari et al.
Awadh Alanazi et al.
The growing recognition of the human microbiome as a key regulator of immune homeostasis has accelerated the application of computational intelligence for microbiome-driven disease understanding and therapeutic design. However, existing mic...
Thermal stability and preliminary antimicrobial evaluation of polylysine-glutathione mixtures [0.03%]
聚赖氨酸-谷胱甘肽混合物的热稳定性和初步抗菌评价
Junsong Song,Xuejun He,Borong Leng et al.
Junsong Song et al.
Background: With the increasing severity of antimicrobial compound resistance, exploring the combined effects of novel antibacterial compounds is of significant research value. Polylysine possesses cationic antibacterial ...
Electrospinning processes: properties, applications, sensor integration nanofiber and biomaterials [0.03%]
电纺丝工艺：性能、应用、传感器集成纳米纤维及生物材料
Ehsan Kianfar
Ehsan Kianfar
Nanofiber production technology has always been interesting as there are a variety of flexible ways to produce one-dimensional organic, inorganic, and constructed nanomaterials with controllable dimensions. Electrospinning is a simple and a...
Corrigendum to "Technology-enabled integration of single-cell transcriptomics and microbiome data identifies RNA-targetable host-microbiota networks in colorectal adenoma" [SLAS Technology (2025) 100365] [0.03%]
“技术赋能的单细胞转录组和微生物组数据整合可识别结直肠腺瘤中可靶向RNA的宿主-微生物群网络”一文的勘误(2025年SLAS技术期刊)
Boyang Ma,Haiyan Hu,Yu Lin et al.
Boyang Ma et al.
Published Erratum
SLAS technology. 2026 Jul 31:100453. DOI:10.1016/j.slast.2026.100453 2026
Cell-state-resolved transcriptomic analysis reveals macrophage-centered pyroptosis-related inflammatory programs in age-related macular degeneration [0.03%]
单细胞转录组分析揭示年龄相关性黄斑变性中以巨噬细胞为中心的焦亡相关炎症程序
Xinxin Li,Fu Gui,Zheng Zheng et al.
Xinxin Li et al.
Background: Age-related macular degeneration (AMD) is accompanied by inflammatory changes in the retinal pigment epithelium/choroid complex, but the cellular sources of pyroptosis-related transcriptional programs in human...
Single-Cell Transcriptomic Characterization of the Tumor Microenvironment in Prostate Cancer Bone Metastases [0.03%]
前列腺癌骨转移肿瘤微环境的单细胞转录组特征分析
Jun Zhao,Desheng Wu
Jun Zhao
Background: Prostate cancer (PCa) bone metastases cause significant morbidity and mortality in advanced disease. The tumor microenvironment (TME) of bone metastases drives disease progression and therapeutic resistance, y...
Improving Predictive Performance of Nucleotide Biosensors via Equivalent Circuit Modeling in Transcriptomic Analysis [0.03%]
通过转录组分析中的等效电路建模提高核苷酸生物传感器的预测性能
Shilpa Gundagatti,Sudha Srivastava,Gayatri Narajji et al.
Shilpa Gundagatti et al.
Accurate consumer-oriented diagnostic devices for cancer screening at an early stage are limited despite the rapid evolution of consumer electronics technology, owing to a high error rate and lack of predictive accuracy. In our study, we pr...
AI/ML-enabled multi-omics integration of host genetics, immunity, and the gut microbiome in Crohn's disease: From diagnosis to theranostics [0.03%]
用于克罗恩病的宿主遗传学、免疫和肠道微生物组的AI/ML enabled多组学整合：从诊断到治疗诊断
Nivedita Kedari,Urjaswee Dey,Desai Sreenija et al.
Nivedita Kedari et al.
Crohn's disease is a long-term inflammatory disorder arising from the interaction of genetic risk factors, immune system dysfunction, and alterations in gut microbiota. Variability in clinical phenotypes and lack of biomarker specificity hi...
Spatial transcriptome and single-cell reveal the role of sorbitol metabolism in hepatocellular carcinoma progression and tumor microenvironment [0.03%]
空间转录组和单细胞揭示山梨醇代谢在肝癌进展和肿瘤微环境中的作用
Xianchun Yang,Yi Cheng,Xing Jiang et al.
Xianchun Yang et al.
Background: Metabolic reprogramming represents a hallmark feature of hepatocellular carcinoma (HCC). As a crucial branch of the polyol pathway, the biological functions and clinical implications of sorbitol metabolism in ...
An adaptable microplate-integrated purification workflow tailored for high-throughput automated parallel amide syntheses [0.03%]
一种适应性微孔板集成净化工作流程，专为高通量自动化平行胺合成而设计
Szabolcs Márk Orosz,Bálint Kis-Tót,András Levente Eged et al.
Szabolcs Márk Orosz et al.
High-throughput automated parallel amide synthesis is essential in early-phase medicinal chemistry; yet, purification of milligram-scale reaction mixtures remains to be a major operational bottleneck. Conventional approaches, including mini...