Low Rates of MASLD Screening in Young Adults With Type 2 Diabetes: A Retrospective Cohort Study [0.03%]
青年2型糖尿病患者中MASLD筛查率低：一项回顾性队列研究
Chloe A de Crecy,Qiang Yang,Mei Liu et al.
Chloe A de Crecy et al.
Context: Regardless of age, metabolic dysfunction-associated steatotic liver disease (MASLD) occurs in 70% of adults with type 2 diabetes (T2D) and increases the risk of metabolic dysfunction-associated steatohepatitis (M...
A polygenic growth score and risk for large for gestational age birth weight [0.03%]
多基因生长评分与大于孕龄儿出生体重风险的关系
Maha Aamir,Maisa Feghali,Lynn Yee et al.
Maha Aamir et al.
Context: Large for gestational age (LGA) birth weight is associated with both short- and long-term health consequences for offspring, and fetal genetics may contribute to risk for LGA birth weight. ...
Effect of vosoritide on genu varum in children with achondroplasia after 1 year in randomized placebo-controlled trials [0.03%]
伏索立肽治疗软骨发育不全儿童膝内翻1年疗效的随机双盲对照研究
Klane K White,Melita Irving,Swati Mukherjee et al.
Klane K White et al.
Achondroplasia is a skeletal dysplasia associated with multisystem complications including genu varum, which causes pain and limits mobility. Vosoritide, a targeted treatment for achondroplasia, improves growth in children and has an establ...
Sarah R Barenbaum,Beverly G Tchang,Louis J Aronne
Sarah R Barenbaum
Obesity is a chronic, multifactorial disease associated with more than 200 complications including type 2 diabetes, cardiovascular disease, obstructive sleep apnea, dyslipidemia, hypertension, premature mortality, and numerous other adverse...
Association between serum phosphate levels within the normal range and all-cause mortality among US adults [0.03%]
美国成年人血清磷水平与全因死亡率之间的关系
Mayuko Yamamoto,Sho Katsuragawa,Yuichi Takashi et al.
Mayuko Yamamoto et al.
Introduction: Hyperphosphatemia is associated with increased mortality in chronic kidney disease (CKD), but the clinical relevance of variation within the normal serum phosphate range remains unclear. This study evaluated...
Missed opportunities for risk reduction: type 1 diabetes management in older adults in DPV and T1DX-QI registries [0.03%]
DPV和T1DX-QI登记处中老年患者在1型糖尿病管理中的缺损之处：减小风险的机遇丢失分析
Kathryn L Fantasia,Stefanie Lanzinger,Saketh Rompicherla et al.
Kathryn L Fantasia et al.
Aims: To examine prescription of guideline-recommended therapies and achievement of treatment targets across the span of older adulthood in type 1 diabetes (T1D) in the United States and Germany/Austria. ...
Anti-Müllerian Hormone Levels Across Phenotypes in Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis [0.03%]
多囊卵巢综合征各表型中抗苗勒管激素水平的系统评价和Meta分析
Patrícia Jorge Schwenck-Carvalho,Giovana De Nardo Maffazioli,Ricardo Santos Simões et al.
Patrícia Jorge Schwenck-Carvalho et al.
Context: Anti-Müllerian hormone (AMH) concentrations are frequently elevated in women with polycystic ovary syndrome (PCOS). However, clinical application is limited by the absence of a standardized cutoff, lack of assay...
Exploratory assessment of preconception phthalate exposure on pregnancy and offspring health outcomes in mice [0.03%]
初步评估孕前邻苯二甲酸盐暴露对小鼠妊娠和子代健康结局的影响
Maryam Afghah,Ansley C Elkins,Paige C Powell et al.
Maryam Afghah et al.
Understanding how endocrine-disrupting chemicals influence reproductive success requires attention to sensitive windows beyond gestation, including the understudied preconception period. In this exploratory pilot study, female CD-1 mice wer...
Body composition changes after 6 and 12 months of dietary weight loss: insights from the DIETFITS trial [0.03%]
饮食减重6个月和12个月后的身体组成变化：来自DIETFITS试验的启示
Sun H Kim,Ji Hye Heo,Kristen Cunanan et al.
Sun H Kim et al.
Context: While popular weight-loss medications have raised concerns about lean mass loss, the normative effects of nonpharmacologic weight loss on body composition remain unclear. ...
Subclinically low BMD in young men is associated with compromised bone microarchitecture and lower lean mass [0.03%]
青年人沉默性低骨密度与较差的骨微结构和较低的去脂体重有关
Jenna B Goulart,Christopher K Kargl,Adam J Sterczala et al.
Jenna B Goulart et al.
Context: Optimizing bone mass accrual early in life is a strategy for mitigating fracture risk in older age. Objective: This study aime...