Cost-effectiveness of personalized medical treatment in acromegaly: a post hoc analysis of the ACROFAST study [0.03%]
肢端肥大症个性化治疗的经济效益分析：ACROFAST研究的事后分析
Montserrat Marques-Pamies,Laura Ricou,Joan Gil et al.
Montserrat Marques-Pamies et al.
Context: Medical treatment of acromegaly is currently performed through a trial-and-error approach using first-generation somatostatin receptor ligands (fgSRLs) as first-line drugs, with an efficacy of 50%. Some biomarker...
Effect of vosoritide on spine morphology in children with achondroplasia: 1-year results from a randomized phase 2 study [0.03%]
生长激素类似物vosoritide对软骨发育不全儿童脊柱形态影响的随机II期临床研究一年结果
Melita Irving,Ravi Savarirayan,Julie E Hoover-Fong et al.
Melita Irving et al.
Achondroplasia is a skeletal dysplasia condition caused by reduced endochondral ossification resulting in disproportionate short stature and skeletal deformities, including thoracolumbar kyphosis (TLK) and spinal stenosis. Vosoritide, the f...
Thyroid and cortisol endocrinopathies and survival in cancer patients treated with immune checkpoint inhibitors in UAE [0.03%]
甲状腺和皮质醇内分泌病与免疫检查点抑制剂治疗的癌症患者的生存率在阿联酋的研究
Mohamed Alqedra,Bara Fahmayee,Lina Wahba et al.
Mohamed Alqedra et al.
Background: Immune checkpoint inhibitors (ICIs) are associated with immune-related adverse events (irAEs) of which endocrinopathies are among the most frequent. This study aimed to identify thyroid and cortisol-related en...
Patient and Caregiver Preferences for Once-Weekly Injection Devices for the Treatment of Growth Hormone Deficiency [0.03%]
患者和护理人员对一次一周生长激素缺乏治疗注射装置的偏好
Jing Voon Chen,Bradley S Miller,Nicky Kelepouris et al.
Jing Voon Chen et al.
Context: Once-weekly long-acting growth hormone (GH) analogue (LA-GHA) treatments offer an alternative to once-daily GH injections for the treatment of children and adults with GH deficiency (GHD). With these new LA-GHA o...
One-hour postload glucose compared to prediabetes criteria as predictive markers of type 2 diabetes in Latin America [0.03%]
一小时负荷血糖与糖尿病前期诊断标准预测拉丁美洲地区2型糖尿病的对比研究
Juan Carlos Lizarzaburu-Robles,William H Herman,Alonso Garro-Mendiola et al.
Juan Carlos Lizarzaburu-Robles et al.
Background: One-hour postload glucose (1h-PG) ≥ 155 mg/dL has been proposed as a marker of prediabetes and risk for type 2 diabetes (T2DM). However, direct comparison with other prediabetic criteria, also in different po...
Bone and body composition by DXA in girls with precocious puberty, premature thelarche, and prepubertal controls [0.03%]
青春期提前、性早熟和青春前期对照组的DXA骨矿物密度及身体成分检测结果
Daniela Fava,Amanda Casirati,Alessia Angelelli et al.
Daniela Fava et al.
Context: Lumbar spine bone mineral density (BMD) rises sharply during puberty; earlier onset, as in central precocious puberty (CPP), may accelerate skeletal maturation and modify bone accrual. ...
Prenatal and postnatal atrazine-induced endocrine and ovarian chemical biotransformation protein disruption in offspring [0.03%]
六氯环己烯致后代内分泌和卵巢化学生物转化蛋白干扰的妊娠和产后调控机制研究
Omotoyosi Adeyanju,Maria Estefanía González-Alvarez,Collins Antwi-Boasiako et al.
Omotoyosi Adeyanju et al.
Atrazine (ATZ) is an endocrine-disrupting chemical, and ATZ exposure during perinatal development is linked to reproductive dysfunction and behavioral abnormalities in adulthood. Gestational ATZ exposure can adversely affect birth weight, f...
Role of antioxidant vitamins in mitigating the health risks from environmental toxicant exposures: a narrative review [0.03%]
抗氧化维生素在减轻环境毒物暴露的健康风险中的作用：叙述性综述
Soundara Viveka Thangaraj,Chigozie Ogwara,Vasantha Padmanabhan
Soundara Viveka Thangaraj
Humans are chronically exposed to numerous environmental pollutants, many of which became widespread due to rapid industrialization and modernization over the past century. These pollutants, including persistent organic pollutants, heavy me...
The Association Between Measures of Prepregnancy Insulin Resistance and Sensitivity with Subsequent Risk of Gestational Diabetes [0.03%]
孕前胰岛素抵抗和敏感性指标与妊娠糖尿病风险的关系
Shalmali Bane,Fei Xu,Assiamira Ferrara et al.
Shalmali Bane et al.
Context: Little is known about the association between prepregnancy homeostasis model assessment of insulin resistance (HOMA-IR) and homeostasis model assessment of β-cell function (HOMA-β) levels and risk of gestationa...
Preferences for Subtyping Primary Aldosteronism: A Discrete Choice Experiment [0.03%]
原发性醛固酮增多症分型的偏好选择实验研究
Maame Esi Woode,Winston Chong,Elisabeth Ng et al.
Maame Esi Woode et al.
Context: Primary aldosteronism (PA) affects 10% to 15% of individuals with hypertension and increases cardiovascular risk. Differentiating between unilateral and bilateral PA determines optimal treatment and typically req...