Comprehensive genetic rescreening improves diagnostic yield in congenital hyperinsulinism [0.03%]
全面的基因复筛可提高先天性高胰岛素血症的诊断率
Jonna M E Männistö,Jayne A L Houghton,Jasmin J Bennett et al.
Jonna M E Männistö et al.
Context: Recent genetic discoveries in congenital hyperinsulinism (HI) and advances in sequencing technology suggest that the diagnostic yield may be improved by rescreening in people with genetically unsolved HI. ...
Melengestrol acetate dysregulates HPP, HPT, and HPI axes, affecting the metamorphosis of Xenopus (Silurana) tropicalis [0.03%]
醋酸美乐孕酮扰乱非洲爪蟾(Mexican leaf frog)的HPP、HPT和HPI轴，影响其 metamorphosis
Diana C Castañeda-Cortés,Paisley E Thomson,Stacey A Robinson et al.
Diana C Castañeda-Cortés et al.
Tadpole development involves several morphological, biochemical, and behavioral transformations regulated by endocrine networks, primarily the hypothalamic-pituitary-thyroid (HPT) and hypothalamic-pituitary-interrenal (HPI) axes. Exposure t...
Antimony: a cryptic metabolism disruptor ubiquitous in food contact materials [0.03%]
隐匿的代谢干扰物——食品接触材料中的锑暴露
Luyu Wang,Spyridoula Gerassimidou,Birgit Geueke et al.
Luyu Wang et al.
Antimony (Sb) is a group 15 metalloid that is used as a catalyst in the production of polyethylene terephthalate (PET) plastic, a common food contact material (FCM). PET accounts for over 44% of single-use beverage packaging units and is al...
Burosumab treatment in an adult with FGF23-mediated hypophosphatemia due to cutaneous skeletal hypophosphatemia syndrome [0.03%]
布索马布治疗FGF23介导的皮肤骨骼低磷血症综合征成人患者低磷血症的有效性
Laura L Tosi,Elmer N Rajah,Austin P Gillies et al.
Laura L Tosi et al.
Context: Cutaneous skeletal hypophosphatemia syndrome (CSHS) is an ultrarare disorder defined by epidermal and/or melanocytic nevi, mosaic skeletal dysplasia, and FGF23-mediated hypophosphatemia. As in other FGF23-mediate...
Impact of antenatal exposure to a mixture of endocrine disruptors on attentional and executive functions in children [0.03%]
孕妇接触内分泌干扰物混合物对儿童注意功能及执行功能的影响
Christophe Barrea,Patrice Dufour,Catherine Pirard et al.
Christophe Barrea et al.
Context: Numerous studies indicate negative associations between early life exposure to endocrine-disrupting chemicals and various aspects of neurodevelopment. However, few have focused on specific cognitive processes. Ad...
Parathyroid histology in normocalcemic and hypercalcemic primary hyperparathyroidism with hypercalciuric renal stones [0.03%]
正常血钙和高血钙原发性甲状旁腺功能亢进症的副甲状腺组织学研究及其与高钙尿肾结石的关系
Bénédicte Blanchard,Safia Hadjadj,Ellie Tang et al.
Bénédicte Blanchard et al.
Context: Hypercalcemic (HPHPT) and normocalcemic primary hyperparathyroidism (NHPT) are distinct conditions with different biological and histological characteristics. Understanding their histological patterns could impro...
Per- and polyfluoroalkyl substances and adolescent bone mineral density: assessing periods of susceptibility [0.03%]
全氟和多氟烷基物质与青少年骨矿密度：评估易感期
Jessie P Buckley,Katherine M Marquess,Joseph M Braun et al.
Jessie P Buckley et al.
Context: Per- and polyfluoroalkyl substances (PFAS) may affect adolescent bone mineral density (BMD), but few studies have examined periods of susceptibility. ...
Advances and challenges in studying effects of EDCs on tissue-resident macrophages in inflammation [0.03%]
环境内分泌干扰物对炎症中组织驻留巨噬细胞影响的研究进展与挑战
Margaret R Bell,Katherine A Walker,Gia M Valdez et al.
Margaret R Bell et al.
Adipose tissue distribution and metabolic profile of young individuals with turner syndrome [0.03%]
特纳综合征年轻患者脂肪分布及代谢特点分析
Varsha Mary Thomas,Philippe Backeljauw,Amy Sanghavi Shah et al.
Varsha Mary Thomas et al.
Objective: Turner syndrome (TS) is the most common sex chromosome abnormality in females. Incidence of cardiometabolic complications is high in TS. Obesity and high visceral adiposity (VA) are additional risk factors. Bod...
David J Handelsman,Grant R Tomkinson
David J Handelsman
Sex differences in adult athletic performance are driven by the 20-to 30-fold increase in testosterone production of male puberty creating larger and stronger muscle, bone and cardiorespiratory functions, and higher hemoglobin creating male...