Clinical burden of classic congenital adrenal hyperplasia and glucocorticoid-related complications: a claims analysis [0.03%]
经典先天性肾上腺皮质增生及其糖皮质激素相关并发症的临床负担：一项理赔分析
Hyunwoo Kim,Vivian H Lin,Ron S Newfield et al.
Hyunwoo Kim et al.
Context: Classic congenital adrenal hyperplasia (CAH) is a rare genetic condition characterized by impaired cortisol and aldosterone synthesis. Historical management required glucocorticoid (GC) therapy to replace cortiso...
Achondroplasia management in the era of targeted therapies: a meta-analysis of C-type natriuretic peptide analogs [0.03%]
靶向疗法时代软骨发育不全管理的meta分析：C型利钠肽类似物
Abul Bashar Mohammad Kamrul-Hasan,Suma Uday,Lakshmi Nagendra et al.
Abul Bashar Mohammad Kamrul-Hasan et al.
Context: No prior meta-analysis has systematically assessed efficacy and safety of C-type natriuretic peptide (CNP) analogs within the context of evolving understanding of FGFR3 biology and achondroplasia natural history....
Disparities in liver-related care among transgender adults with steatotic liver disease: a retrospective cohort study [0.03%]
与脂肪性肝病跨性别成人之间与肝脏相关护理的差异：一项回顾性队列研究
Maria Ortega Abad,Leandro Sierra,Nikki Duong et al.
Maria Ortega Abad et al.
Background: Transgender (TGD) adults experience healthcare disparities across multiple domains, yet care for steatotic liver disease (SLD) remains uninvestigated. ...
Inhibiting hepatocytes MAGL alleviates osteoporosis caused by high-fat diet-induced liver fibrosis in male mice [0.03%]
抑制高脂饮食诱导的肝纤维化小鼠肝细胞MAGL可缓解骨质疏松症
Qing Zhang,Zhixiang Lin,Peng Wang et al.
Qing Zhang et al.
Hepatic osteoporosis is mediated through the liver-bone axis, but the precise mechanisms underlying osteoporosis in severe liver disease remain elusive. A high-fat diet can induce hepatic steatosis, which may subsequently progress to liver ...
Relevance of the KATP channel function for the basal insulin hypersecretion of islets from female NZO mice [0.03%]
钾通道功能与雌性NZO小鼠胰岛基础胰岛素高分泌的相关性研究
Melissa Asuaje Pfeifer,Joana Brozek,Katharina Grupe et al.
Melissa Asuaje Pfeifer et al.
Context: The polygenic New Zealand obese (NZO) mouse model displays the characteristics of early type 2 diabetes: fasting hyperglycemia, hyperinsulinemia, and insulin resistance. The expression of the ATP-sensitive potass...
Transient gonadotropin suppression by exogenous testosterone decreases INSL3 in early puberty in boys with constitutional delay of growth and puberty [0.03%]
外源性睾酮暂时抑制促性腺激素可降低康斯坦丁发育迟缓和青春期男孩早期INSL3的水平
Taneli Raivio,Mila Tanner,Kirsi Vaaralahti et al.
Taneli Raivio et al.
We investigated circulating insulin-like peptide 3 (INSL3) in boys with constitutional delay of growth and puberty treated with exogenous testosterone (T) or oral letrozole (Lz). Twenty-eight boys were randomized to Lz (2.5 mg/day; n = 15) ...
Preoperative eGFR, age, and sex predict early postoperative renal changes in acromegaly [0.03%]
术前eGFR、年龄和性别可预测肢端肥大症术后早期肾变化
Keiko Tomiyama,Izumi Fukuda,Mikiko Okazaki-Hada et al.
Keiko Tomiyama et al.
Objective: Acromegaly induces renal alterations. However, early postoperative renal changes following rapid hormonal correction remain unclear. We assessed early postoperative changes in estimated glomerular filtration ra...
Feasibility, reproducibility, and cold-induced energy expenditure using whole-room calorimetry in adults and children [0.03%]
成人和儿童使用整体室热学测量的可行性、重现性和冷诱导的能量消耗
Paige Cheveldayoff,Bader Alamri,Dongdong Wang et al.
Paige Cheveldayoff et al.
Context: To understand energy balance, whole-room indirect calorimetry (WRIC) allows for accurate measurement of energy expenditure (EE). Objective: ...
The role of hormonal markers in predicting reproductive lifespan in girls with Turner syndrome-a retrospective study [0.03%]
青春期女孩特纳综合征中激素标志物与生殖寿命的关系回顾性研究
Sanne van der Coelen,Theo Sas,Annette Richter-Unruh et al.
Sanne van der Coelen et al.
Context: Early prediction of ovarian reserve is essential to improve fertility counseling in girls with Turner syndrome (TS). Objective: ...
Growth hormone retesting for idiopathic isolated growth hormone deficiency during and after puberty: a systematic review [0.03%]
青春期期间和之后对特发性孤立性生长激素缺乏症进行生长激素复检的系统评价
Joeri Vliegenthart,Deveney F Wols,Jan M Wit et al.
Joeri Vliegenthart et al.
Context: Idiopathic isolated growth hormone deficiency (IIGHD) is difficult to diagnose due to the day-to-day variation in growth hormone (GH) secretion and limitations of GH stimulation testing (GHST). Although recombina...