Weight loss lifestyle intervention and bone health hormonal markers in type 2 diabetes: analysis from look AHEAD study [0.03%]
针对2型糖尿病患者的减肥生活方式干预与骨健康激素指标的相关性——取自“Look AHEAD”研究的数据进行的分析
Jiahuan Helen He,Chigolum P Oyeka,Jianqiao Ma et al.
Jiahuan Helen He et al.
Context: Intensive lifestyle interventions (ILI) in people with type 2 diabetes (T2D) not only promote weight loss but are also associated with bone loss and increased fracture risk. The hormonal mechanisms regulating cal...
Three-dimensional characterization of adenomyosis in female mice: Toward a novel system for drug efficacy evaluation [0.03%]
小鼠子宫腺肌病的三维表征：建立新的药物疗效评估体系走向新型系统用于药物疗效评估中的小鼠子宫腺肌病的三维特征
Chihiro Ishizawa,Takehiro Hiraoka,Shizu Aikawa et al.
Chihiro Ishizawa et al.
Adenomyosis is an intractable gynecological disorder that can give rise to severe pelvic pain, heavy menstrual bleeding, and infertility, predominantly affecting women of reproductive age. The limited efficacy of current pharmacological int...
Greater reduction in the proinsulin-C-peptide ratio with a ketogenic vs control diet in patients with type 2 diabetes [0.03%]
与对照饮食相比，酮体饮食在2型糖尿病患者中降低 proinsulin-C 肽比值的作用更大
Marian L Yurchishin,Amanda R Finn,Lauren A Fowler et al.
Marian L Yurchishin et al.
Context: The proinsulin to C-peptide (PICP) ratio reflects beta-cell stress and has been shown to decrease following diet-induced weight loss. Objective: ...
Association between high DHEAS in 7-year-old girls and metabolic features 4 years after menarche [0.03%]
女孩7岁时DHEAS水平升高与初潮后4年代谢特征之间的关系
Ana Pereira,Gordon B Cutler,German Iñiguez et al.
Ana Pereira et al.
Background: Premature adrenarche is linked to increased adiposity, enhanced adrenal 11-oxygenated C19 androgen production, and adverse metabolic profiles in childhood. However, it remains unclear whether early elevations ...
Thyroid hormones are associated with pituitary and thyroid volume in a population-based study [0.03%]
甲状腺激素与基于人群的垂体和甲状腺体积的研究有关
Annemarie Luise Weihs,Katharina Wittfeld,Robin Bülow et al.
Annemarie Luise Weihs et al.
There is increasing evidence that even a small variation in thyroid function, even within the reference range, is associated with adverse clinical outcomes. Furthermore, there exists a substantial interindividual variation of thyroid functi...
Disparities in utilization of high-volume thyroid surgeons for Graves disease: a statewide analysis [0.03%]
Graves病高手术量甲状腺外科医生利用率的差异——来自全州范围的分析
Steven Xie,Catherine B Jensen,Aayushi Sinha et al.
Steven Xie et al.
Context: For patients with Graves disease undergoing surgery, the American Thyroid Association guidelines recommend referral to a high-volume thyroid surgeon (HVTS). However, factors limiting patient utilization of an HVT...
Scalp hair and serum iodine as potential biomarkers for iodine intake and their association with the thyroid function [0.03%]
头皮头发和血清碘作为潜在的碘摄入生物标志物及其与甲状腺功能的关系研究
Yozen Fuse,Yo Kunii,Nobu Tsukada et al.
Yozen Fuse et al.
Context: The association of iodine nutritional status with thyroid function in iodine-replete countries is controversial and more sensitive biomarkers than urinary iodine concentration is required. ...
Longitudinal dynamics of fasting plasma uridine in the preclinical stage of type 1 diabetes [0.03%]
1型糖尿病临床前期空腹血浆尿苷的纵向动态变化
Qiutang Xiong,Chelsea Jang,Kevin Wang et al.
Qiutang Xiong et al.
Context: Elevated blood uridine levels have been reported in children with newly diagnosed type 1 diabetes (T1D); however, their relevance to disease onset remains unclear. ...
Associations of selected atypical non-neuroendocrine cancers with multiple endocrine neoplasia type 1 [0.03%]
多种内分泌肿瘤1型与某些非神经内分泌癌的关联研究
Iina Yliaska,Joona Tapio,Timo A Kumpula et al.
Iina Yliaska et al.
Context: Multiple endocrine neoplasia type 1 (MEN1) is a hereditary tumor predisposing syndrome, characterized by typical neuroendocrine tumors in parathyroid, pituitary, and endocrine pancreas tissues ("3P"). MEN1 is als...
Clinical and genetic characteristics of head and neck paragangliomas from China featuring Sino-European comparisons [0.03%]
中国头颈部副神经节瘤的临床及遗传特征并对比中欧差异性
Jun Liu,Yingxian Pang,Jianing Yue et al.
Jun Liu et al.
Context: Head and neck paragangliomas (HNPGLs) are tumors of parasympathetic origin, predominantly associated with pseudohypoxia and pathogenic variants (PVs) in succinate dehydrogenase (SDH) subunits, mainly based on stu...