A worldwide perspective on clinical characteristics and treatment of youth with monogenic diabetes in the SWEET registry [0.03%]
SWEET注册研究中的单基因糖尿病儿童的临床特征及治疗的全球概述
Lily Deng,Stefanie Lanzinger,Kristina Casteels et al.
Lily Deng et al.
Aims: To characterize youth with monogenic diabetes worldwide in the SWEET database and define trends in clinical care and outcomes. Methods: ...
Placental gene signatures associated with high neonatal adiposity: role for immune cell activation [0.03%]
与新生儿脂肪堆积相关的胎盘基因特征：免疫细胞活化的角色
Jason Laird,Deepak Venkataraman,Hannah Yen et al.
Jason Laird et al.
Fetal fat accumulation is an important indicator of the nutritional environment in pregnancy and placental function. Excessive fat accretion leading to high adiposity at birth, however, can increase a child's long-term risk for obesity and ...
Adherence to growth hormone treatment in the transition age: A prospective observational multicenter study [0.03%]
生长激素治疗向成人期过渡的依从性：一项前瞻性多中心研究
Chiara Guzzetti,Paula van Dommelen,Letizia Casula et al.
Chiara Guzzetti et al.
Context: Adherence can be an issue in patients taking growth hormone (GH). Objective: To evaluate adherence to GH treatment during the ...
Insulin receptor expression and its association with hyperinsulinemia in triple negative breast cancer [0.03%]
胰岛素受体的表达及其与三阴性乳腺癌高胰岛素血症的相关性
Alexis J Engel,Krupa Samuel,Ilana R Bass et al.
Alexis J Engel et al.
Purpose: Hyperinsulinemia and tumor insulin receptor (IR) expression have been associated with triple negative breast cancer (TNBC) progression in preclinical models. We aimed to evaluate the expression of the IR, IGF-1 r...
Visceral adiposity does not explain increased diabetes rates in Black and Hispanic people in NHANES 2011-2018 [0.03%]
内脏脂肪不能解释NHANES 2011-2018调查中黑人和西班牙裔糖尿病患病率较高的现象
Leah S Alemu,Karishma Chopra,Rajesh K Jain
Leah S Alemu
Context: Asian, Black, and Hispanic individuals in the United States have higher rates of diabetes mellitus (DM) when compared to White individuals. It is not clear if these differences could be related to visceral adipos...
Social deprivation, race, and metabolic syndrome in patients with polycystic ovary syndrome [0.03%]
社会剥夺、种族与多囊卵巢综合征患者代谢综合征的关系
Iris T Lee,Shakira King,Naria Sealy et al.
Iris T Lee et al.
Context: Social determinants of health (SDoH) are a key contributor to cardiovascular disease (CVD) risk, including metabolic syndrome (MetSyn), as well as racial disparities in that risk. It is unknown if SDoH are associ...
Free testosterone independently predicts metabolic syndrome severity in U.S. adolescent girls aged 12-19 years [0.03%]
游离睾酮可独立预测美国年龄在12-19岁少女代谢综合征的严重程度
Christopher R McCartney,Aaron F Pannone,Su Hee Kim et al.
Christopher R McCartney et al.
Context: Hyperandrogenemia is associated with increased risks for metabolic syndrome in asymptomatic women and women with polycystic ovary syndrome. The relationship between hyperandrogenemia and metabolic syndrome in ado...
Comprehensive genetic rescreening improves diagnostic yield in congenital hyperinsulinism [0.03%]
全面的基因复筛可提高先天性高胰岛素血症的诊断率
Jonna M E Männistö,Jayne A L Houghton,Jasmin J Bennett et al.
Jonna M E Männistö et al.
Context: Recent genetic discoveries in congenital hyperinsulinism (HI) and advances in sequencing technology suggest that the diagnostic yield may be improved by rescreening in people with genetically unsolved HI. ...
Melengestrol acetate dysregulates HPP, HPT, and HPI axes, affecting the metamorphosis of Xenopus (Silurana) tropicalis [0.03%]
醋酸美乐孕酮扰乱非洲爪蟾(Mexican leaf frog)的HPP、HPT和HPI轴，影响其 metamorphosis
Diana C Castañeda-Cortés,Paisley E Thomson,Stacey A Robinson et al.
Diana C Castañeda-Cortés et al.
Tadpole development involves several morphological, biochemical, and behavioral transformations regulated by endocrine networks, primarily the hypothalamic-pituitary-thyroid (HPT) and hypothalamic-pituitary-interrenal (HPI) axes. Exposure t...
Antimony: a cryptic metabolism disruptor ubiquitous in food contact materials [0.03%]
隐匿的代谢干扰物——食品接触材料中的锑暴露
Luyu Wang,Spyridoula Gerassimidou,Birgit Geueke et al.
Luyu Wang et al.
Antimony (Sb) is a group 15 metalloid that is used as a catalyst in the production of polyethylene terephthalate (PET) plastic, a common food contact material (FCM). PET accounts for over 44% of single-use beverage packaging units and is al...