The 129S1/SvImJ Mouse Strain Is Resistant to the Effects of Early Embryonic Alcohol and Other Sonic Hedgehog Inhibitors [0.03%]
129S1/SvImJ品系小鼠抵抗早期胚胎酒精及其它 sonic hedgehog 抑制剂影响的能力较强
Ruby L Lapham,Eric W Fish,Scott E Parnell
Ruby L Lapham
Background: Prenatal alcohol exposure can cause fetal alcohol syndrome, but genetic variation can account for some of the observed differential susceptibility to alcohol-induced birth defects. Here we investigate an inbre...
Gastroschisis: Is the Combination of Diagnosis and Procedure Code Sufficient for Case-Confirmation? [0.03%]
胃外翻：诊断和手术编码的组合是否足以确认病例？
Dianna Contreras,Brandon Miura-Akagi,Michael Gibbons et al.
Dianna Contreras et al.
Introduction: Timely, accurate reporting is essential for population-based surveillance of birth defects. Searching specific diagnosis codes in hospital discharge data is standard practice for identifying potential cases;...
Shuyue Deng,Xinyi Liu,Siyu Chen et al.
Shuyue Deng et al.
Objective: To explore the influence of choline and its derivatives (betaine, phospholipids) on the occurrence and development of neural tube defects. Meth...
First Detection of 1p36 Deletion by Whole-Exome Sequencing in a Tunisian Patient [0.03%]
全外显子组测序在突尼斯患者中检测到的第一例1p36缺失
Nesrine Kerkeni,Maher Kharrat,Lilia Kraoua et al.
Nesrine Kerkeni et al.
Study objective: We reported a rare case of 1p36 deletion syndrome diagnosed using whole-exome sequencing (WES) in a Tunisian neonate, and to highlight the utility of WES in detecting structural variants, particularly in ...
Case Reports
Birth defects research. 2026 Jan;118(1):e70017. DOI:10.1002/bdr2.70017 2026
The Impact of Chlamydia Treatment During Pregnancy on Birth Defects in New York State [0.03%]
纽约州孕期沙眼衣原体治疗对出生缺陷的影响
Elizabeth M Boos,Meredith Howley,Tomoko Udo et al.
Elizabeth M Boos et al.
Background: Chlamydia trachomatis (CT) diagnoses are highest among females of reproductive age. Yet, little is known about adverse infant outcomes associated with treatment for CT infections during pregnancy, including bi...
The Creation of a Weight of Evidence Scoring Database for Risk Factors for Adverse Impacts to Birth Outcomes Using Expert Elicitation [0.03%]
基于专家意见的不良妊娠结局风险因素重量证据评分数据库的建立
Paul J Villeneuve,Ann Aschengrau,Michelle L Bell et al.
Paul J Villeneuve et al.
Background: Adverse birth outcomes are important public health measures and account for a substantial public health burden. There is considerable diversity of these health endpoints, as well as in the many factors suspect...
Impact of Maternal Riboflavin Deficiency on the Growth and Development of Offspring Rats [0.03%]
母体核黄素缺乏对大鼠子代生长发育的影响
S Gomathi,H Radha,G Bhanuprakash Reddy et al.
S Gomathi et al.
Background: Riboflavin (vitamin B2) is crucial for energy metabolism and several physiological processes. Pregnant women have a greater chance of being riboflavin-deficient, but its effects on offspring development remain...
Maternal Diabetes Types and the Risk of Pregnancy Loss and Specific Malformations in the Infant [0.03%]
母亲糖尿病类型与妊娠丢失和婴儿畸形风险的关系
Pin-Chia Huang,Krista F Huybrechts,Loreen Straub et al.
Pin-Chia Huang et al.
Background: To compare the risk of pregnancy loss and the prevalence of specific major congenital malformations (MCMs) in newborns between mothers with pregestational diabetes mellitus (DM) type 1 (T1DM) and type 2 (T2DM)...
Staff Experiences With Electronic Initial Case Reports for Birth Defects Surveillance in Texas [0.03%]
关于电子初始病例报告的员工体验： texas出生缺陷监测项目中的应用
Alexandra Koops,Rebecca Howell,Rachel P Allred et al.
Alexandra Koops et al.
Background: Electronic case reporting (eCR) is increasingly used by public health agencies to support disease surveillance. Its utility for birth defects surveillance remains unexplored. This project aimed to evaluate bir...
Maternal Folic Acid Supplement Use, Folate Intake, and Preterm Birth Among Infants With Spina Bifida [0.03%]
孕妇补充叶酸、叶酸摄入量与脊柱裂婴儿的早产关系
Renata H Benjamin,Katherine L Ludorf,Rachel P Allred et al.
Renata H Benjamin et al.
Background: We sought to assess the extent to which folic acid supplementation and dietary folate intake are associated with preterm delivery among infants with spina bifida. ...