A Tiered Genetic Diagnostic Approach in Newborns With Major Congenital Anomalies: Experience From a Tertiary NICU [0.03%]
新生儿重大先天畸形的分层遗传学诊断方法：一家三级NICU的经验总结
Hatice Mutlu,Ece Eker,Yasemin Ezgi Köstekci et al.
Hatice Mutlu et al.
Background: Major congenital anomalies (MCAs) are a leading cause of neonatal morbidity and mortality and frequently reflect underlying chromosomal, copy number, or single-gene defects. In neonates with multiple MCAs, ear...
Maternal Hypertension, Diabetes, and Preterm Birth Risk Among Infants With Trisomy 21 in Texas, 1999-2018 [0.03%]
1999-2018年期间德克萨斯州唐氏综合征婴儿母亲的高血压、糖尿病及早产风险
Fatima R Sheriff,Renata H Benjamin,Qian Xiao et al.
Fatima R Sheriff et al.
Background: The preterm birth rate among infants with trisomy 21 is more than twice the rate among the general population. Maternal hypertension and diabetes are established risk factors for preterm birth in the general p...
Introduction to the 2026 National Birth Defects Prevention Network Virtual Issue [0.03%]
2026年全美出生缺陷预防网络虚拟期号前言
Sarah C Fisher,Wendy N Nembhard
Sarah C Fisher
Enumeration of Microscopic Ovarian Structures in Rodents: Best Practices and Toxicological Significance [0.03%]
啮齿类动物卵巢显微结构计数的最佳实践及其毒理学意义
P S Coder,J D Vidal,C A Picut et al.
P S Coder et al.
Background: Reproductive toxicity studies for industrial and agricultural chemicals require enumeration of ovarian follicles (OF). In recent years, the enumeration of corpora lutea (CL) in histological sections has also b...
Inpatient Hospitalization Charges for Children With Birth Defects in Texas, 2021-2023 [0.03%]
得克萨斯州2021-2023年出生缺陷儿童住院费用
Dayana Betancourt,Charles Shumate,Henal Gandhi et al.
Dayana Betancourt et al.
Introduction: Children with birth defects often require complex medical care, contributing to increased healthcare costs. Understanding the economic burden of birth defects is important for resource planning, but recent T...
Maternal and Early Developmental Effects of Perinatal Exposure to Therapeutically Relevant Doses of Common Nonsteroidal Anti-Inflammatory Drugs in Rats [0.03%]
大鼠围产期接触临床相关剂量的常见非甾体抗炎药的母体和早期发育效应
Sara Tawany Caetano Dos Santos,Reggina Lorena Mellado Castro,Luara Magalhães et al.
Sara Tawany Caetano Dos Santos et al.
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used during pregnancy, yet information on their developmental safety during sensitive perinatal windows remains limited. This study evaluated the matern...
Preconception and Early Pregnancy Exposure to Ambient Air Pollution and Risk of Cleft Lip and/or Palate: A Case-Control Study Using Single-Pollutant, Multi-Pollutant, and Mixture-Based Analyses [0.03%]
基于单一污染物、多污染组合和混合物的配对病例对照研究评估孕前及早期孕期接触室外空气污染与儿童发生唇腭裂风险的关系
Fatih Sezer,Sıddika Songül Yalçın,Murat Kara et al.
Fatih Sezer et al.
Background: Cleft lip and/or palate (CLP) is among the most common congenital anomalies worldwide. Ambient air pollution has emerged as an important environmental exposure potentially contributing to its multifactorial et...
Intentional Dexketoprofen Overdose During Pregnancy: Maternal and Fetal Outcomes in Three Cases [0.03%]
.dex-Profen妊娠期故意过量服用事件：3例母亲和胎儿结局报告
Nusret Uysal,Mesut Gungor,Baris Karadas et al.
Nusret Uysal et al.
Background: Dexketoprofen trometamol is a widely used short-acting nonsteroidal anti-inflammatory drug. Despite its widespread clinical use, pregnancy-specific safety data for dexketoprofen as an individual agent are lack...
Case Reports
Birth defects research. 2026 Aug;118(8):e70101. DOI:10.1002/bdr2.70101 2026
Fetal Superior Mesenteric Artery Peak Systolic Velocity as a Marker of Prenatal Bowel Inflammation in Gastroschisis: A Case-Control Study [0.03%]
先天性腹壁缺陷胎儿肠管炎症的超声标志-胎盘循环峰收缩期血流速度的病例对照研究
Renata Jaczyńska,Boyana Mikulska,Magda Rybak-Krzyszkowska et al.
Renata Jaczyńska et al.
Objective: This study aimed to evaluate whether peak systolic velocity (PSV) in the fetal extra-abdominal superior mesenteric artery (SMA) is a useful prenatal marker of bowel inflammation in gastroschisis (GS), which man...
Maternal Stressors and Social Support in Early Pregnancy and the Risk of Stillbirth Among Fetuses With Birth Defects: Exploring Effect Modification by Race/Ethnicity [0.03%]
孕期母体压力和社会支持与胎儿缺陷儿 stillbirth 的风险：探索种族/民族的效应修饰作用
Meredith M Howley,Jada M Scott,Eva M Williford et al.
Meredith M Howley et al.
Background: Prenatal stress and social support are associated with adverse birth outcomes, including stillbirth, in the general population. Their relationship to stillbirth among fetuses with birth defects is unclear. Usi...