Neural Tube Defects (NTDs) and Modifiable Maternal Behavioral Risks in a Low-Resource Setting: Evidence From a Multicenter, Hospital-Based, Case-Control Study in Ethiopia [0.03%]
基于医院的案例对照研究：埃塞俄比亚低资源环境下神经管缺陷与可改变的母体行为风险因素证据
Rahel T Asrat,Abel Gedefaw,Tafese Bosha et al.
Rahel T Asrat et al.
Background: Neural tube defects (NTDs) are among the most common and severe congenital anomalies, with an especially high prevalence in Ethiopia. This study aimed to identify potential maternal risk and protective factors...
Multicenter Study
Birth defects research. 2026 May;118(5):e70055. DOI:10.1002/bdr2.70055 2026
Computational Studies of Satureja hortensis Phytochemicals as Inhibitors of AP-1 (FOS/JUN) Activation in Valproic Acid Teratogenicity [0.03%]
药用植物Satureja hortensis中的化学成分通过抑制AP-1（FOS / JUN）活化来对抗戊酸钠致畸性的计算研究
Vindya Nagarakere Shankara,Syed Sagheer Ahmed,Bharathi Doddla Raghunathanaidu
Vindya Nagarakere Shankara
Background: Valproic acid (VPA) is a widely used antiepileptic drug and known teratogen that induces developmental defects in part via aberrant activation of the AP-1 (c-Fos/c-Jun) transcription factor pathway. We investi...
Maternal Fish Intake in the Year Prior to Conception and Birth Defects, National Birth Defects Prevention Study, 1997-2011 [0.03%]
我国1997～2011年出生缺陷监测人群中孕前鱼类摄入量与出生缺陷的关系研究
Dorothy Kim Waller,Zeyu Miao,Renata H Benjamin et al.
Dorothy Kim Waller et al.
Background: Epidemiologic data on the association between maternal fish intake and birth defects are sparse. Our objective was to assess associations between maternal fish intake and 52 different birth defects, most of wh...
Sirenomelia: A Review of European Prevalence Data and Epidemiological Analysis of 17 Cases Registered in Wales [0.03%]
美人鱼综合征：欧洲地区流行病学数据分析及威尔士注册登记的17例病例回顾分析
Chris Emmerson,Michael Olson,Ceri Williams et al.
Chris Emmerson et al.
Background: Sirenomelia is a rare congenital condition most notably characterized by a single lower limb. Previous studies have suggested a prevalence of approximately 1 per 100,000 births. However, in Wales 17 cases were...
Potential Effects of Prepubertal Exposure to Perfluorooctane Sulfonic Acid on the First Wave of Folliculogenesis in Young CD-1 Mice [0.03%]
幼年暴露全氟辛烷磺酸对CD-1小鼠初次卵泡发育的影响研究
Bounleut Phanavanh,Jalina Moore,Amy Inselman et al.
Bounleut Phanavanh et al.
Background: Perfluorooctane sulfonic acid (PFOS) belongs to a group of synthetic chemicals referred to as per- and polyfluoroalkyl substances (PFAS) that are known to degrade slowly. Exposure to PFOS has been reported to ...
Joint Position Statement from the Society for Birth Defects Research and Prevention, the Organization of Teratology Information Specialists, and the Developmental Neurotoxicology Society: A Call for Implementation of Risk Evaluation and Mitigation Strategies to Reduce Prenatal Exposure to Valproate [0.03%]
美国出生缺陷学会、妊娠毒性信息专家组织和发育神经毒理学协会联合声明：实施风险评估和缓解策略减少孕期接触丙戊酸钠的风险
Almut G Winterstein,Elizabeth Conover,Joan D Garey et al.
Almut G Winterstein et al.
Analysis of Prevalence and Mortality Among Neonates and Children With Intestinal Atresia: A Multinational Study, 1974-2015 [0.03%]
1974-2015年肠梗阻流行病学和死亡率的多国研究分析：1974-2015年肠道闭锁新生儿及儿童发病率和死亡率的流行病学 multinational study
Angie Carreño,Maria Paula Aguilera,Lina Ibañez et al.
Angie Carreño et al.
Introduction: Small intestinal atresia (SIA) consists of a congenital obstruction of the lumen of the duodenum, jejunum, or ileum with varying severity. The aim of the investigation was to analyze the prevalence and morta...
Mind the Litter: The Critical Role of Intralitter Variables in Reproductive and Developmental Toxicology Research [0.03%]
谨防巢效：生殖和发育毒理学研究中易忽略的窝内变量效应
Lauren T L Brown,Megan E Cull,Delaine Pereira et al.
Lauren T L Brown et al.
Background: Animal models remain essential for understanding developmental toxicology, providing insights into how in utero exposures affect fetal and placental outcomes. Litter-bearing species are widely used due to thei...
The Effect of Maternal Pertussis Vaccination on Neonatal Health Outcomes in the Dutch Pregnancy Drug Register [0.03%]
荷兰妊娠药物登记中心关于母体破伤风疫苗对新生儿健康影响的研究
Petra J Woestenberg,Veronique Y F Maas,Maud de Feijter et al.
Petra J Woestenberg et al.
Background: The currently high pertussis-related morbidity and mortality among infants has led to increased international attention for pertussis vaccination during pregnancy. We studied the safety of maternal pertussis v...