Catherine A Lebel,Carly A McMorris,Preeti Kar et al.
Catherine A Lebel et al.
Background: Prenatal and postnatal adversities, including prenatal alcohol exposure (PAE), prenatal exposure to other substances, toxic stress, lack of adequate resources, and postnatal abuse or neglect, often co-occur. T...
Women's periconceptional lowered carbohydrate intake and NTD-affected pregnancy risk in the era of prefortification with folic acid [0.03%]
产前强制性叶酸强化时代妇女妊娠前后低碳水化合物摄入与影响胎儿患神经管缺陷风险的关系研究
Gary M Shaw,Wei Yang
Gary M Shaw
Background: A recent study observed women's restricted carbohydrate diet in the year before conception was associated with increased risk of neural tube defect (NTD)-affected pregnancies. That study corresponded to the er...
Mary J O&#x;Connor,Larissa C Portnoff,Michael Lebsack-Coleman et al.
Mary J O&#x;Connor et al.
Background: The teratogenic effects of prenatal alcohol exposure (PAE) have been extensively documented over the course of 45 years of research and psychiatric problems are pervasive in this population. In adults with PAE...
Clinical Trial
Birth defects research. 2019 Jul 15;111(12):822-828. DOI:10.1002/bdr2.1465 2019
The effects of nifedipine and ivabradine on the functionality of the early rat embryonic heart. Are these drugs a risk in early human pregnancy? [0.03%]
尼卡地平和伊伐布雷在早期大鼠心脏功能中的影响。这些药物会在人类早期妊娠中带来风险吗？
Helen E Ritchie,Carolina Telenius,Elin Gustaffson et al.
Helen E Ritchie et al.
Background: When the human heart begins its earliest contractions from day 21, it lacks a functional autonomic nerve supply. Instead, contractions are generated by regular calcium transients later augmented by the funny c...
Ethanol and cannabinoids interact to alter behavior in a zebrafish fetal alcohol spectrum disorder model [0.03%]
乙醇和大麻素相互作用可改变斑马鱼胎儿酒精谱系障碍模型的行为反应
Oswald Boa-Amponsem,Chengjin Zhang,Somnath Mukhopadhyay et al.
Oswald Boa-Amponsem et al.
Background: Recent work suggests that endocannabinoids (eCBs) may signal through the sonic hedgehog signaling pathway. We therefore hypothesized that combined ethanol and eCB exposure during defined stages of zebrafish em...
Response to comments on "Reproductive toxicology studies supporting the safety of molindone, a dopamine receptor antagonist" [0.03%]
关于“支持单胺能受体拮抗剂盐酸莫林酮安全性生殖毒理学研究”的回复
Gopakumar Gopalakrishnan,Shivaputhrappa Ganiger,Tacey E K White et al.
Gopakumar Gopalakrishnan et al.
Kim Newsome,C J Alverson,Jennifer Williams et al.
Kim Newsome et al.
Background: Pregnant women with influenza are more likely to have complications, but information on infant outcomes is limited. Methods: ...
Prepregnancy asthma and the subsequent risk of central nervous system defects in offspring [0.03%]
孕前哮喘与后代中枢神经系统缺陷的后续风险关系研究
Nathalie Auger,Laura Arbour,Adeline Kabageni et al.
Nathalie Auger et al.
Background: The relationship between childhood asthma and central nervous system defects in offspring is poorly understood. We assessed if childhood asthma was associated with the risk of having an infant with neural tube...
Maternal residential exposure to specific agricultural pesticide active ingredients and birth defects in a 2003-2005 North Carolina birth cohort [0.03%]
北卡罗来纳州一项基于2003至2005年出生队列的母居农业杀虫剂活性成分暴露与出生缺陷的研究
Kristen M Rappazzo,Joshua L Warren,Angel D Davalos et al.
Kristen M Rappazzo et al.
Background: Previously we observed elevated odds ratios (ORs) for total pesticide exposure and 10 birth defects: three congenital heart defects and structural defects affecting the gastrointestinal, genitourinary and musc...
Limb body wall complex: Its delineation and relationship with amniotic bands using clustering methods [0.03%]
肢体体壁复合征及其与羊膜带综合征的关系——一种聚类方法的研究
Monica Rittler,Hebe Campaña,Fernando A Poletta et al.
Monica Rittler et al.
Background: Despite the numerous reports on the limb body wall complex (LBWC), this association has never been adequately defined. Amniotic bands (AB) are frequently present but their role remains unclear. Since most repo...