Short-term results of patients with neural tube defects followed-up in the Konya region, Turkey [0.03%]
土耳其科尼亚地区神经管缺陷患儿的短期结果分析
Alaaddin Yorulmaz,Murat Konak
Alaaddin Yorulmaz
Background: Additional congenital anomalies have often been found in patients with neural tube defect (NTD). We aimed to find out the clinical features, short term prognosis, treatment approaches, and systemic anomalies o...
Testicular function in cultured postnatal mouse testis fragments is similar to that of animals during the first wave of spermatogenesis [0.03%]
培养的小鼠产后睾丸片段的生精功能与第一次精子发生波高峰时期的动物相似
Lisa M Pence,Thomas C Schmitt,Richard D Beger et al.
Lisa M Pence et al.
Background: Previously, we evaluated optimal organ culture conditions to produce elongated spermatids in an in vitro mouse testis culture system. However, differences in testicular function between the cultured testis fra...
An insight into the role of the death receptor CD95 throughout pregnancy: Guardian, facilitator, or foe [0.03%]
CD95死亡受体在妊娠全程的作用机制：守护者、合作者还是敌人？
Lucas Sagrillo-Fagundes,Josianne Bienvenue-Pariseault,Patrick Legembre et al.
Lucas Sagrillo-Fagundes et al.
The prototype death receptor CD95 (Fas) and its ligand, CD95L (FasL), have been thoroughly studied due to their role in immune homeostasis and elimination of infected and transformed cells. The fact that CD95 is present in female reproducti...
Differential neuroimaging indices in prefrontal white matter in prenatal alcohol-associated ADHD versus idiopathic ADHD [0.03%]
孕期酒精相关的注意力缺陷多动障碍与原发性注意力缺陷多动障碍在前额叶白质的神经影像学指标差异性研究
Joseph O&#x;Neill,Mary J O&#x;Connor,Victor Yee et al.
Joseph O&#x;Neill et al.
Background: Attention deficit-hyperactivity disorder (ADHD) is common in fetal alcohol spectrum disorders (FASD) but also in patients without prenatal alcohol exposure (PAE). Many patients diagnosed with idiopathic ADHD m...
Comparative Study
Birth defects research. 2019 Jul 15;111(12):797-811. DOI:10.1002/bdr2.1460 2019
Hypospadias risk is increased with maternal residential exposure to hormonally active hazardous air pollutants [0.03%]
母亲暴露于具有内分泌活性的有害空气污染物中会增加阴茎尿道下裂的风险
Kunj R Sheth,Erin Kovar,Jeffrey T White et al.
Kunj R Sheth et al.
Background: With the increasing birth prevalence of hypospadias, there is growing concern for pollutant exposure interfering with normal penile development. We assess the association between hypospadias and hormonally act...
Catherine A Lebel,Carly A McMorris,Preeti Kar et al.
Catherine A Lebel et al.
Background: Prenatal and postnatal adversities, including prenatal alcohol exposure (PAE), prenatal exposure to other substances, toxic stress, lack of adequate resources, and postnatal abuse or neglect, often co-occur. T...
Women's periconceptional lowered carbohydrate intake and NTD-affected pregnancy risk in the era of prefortification with folic acid [0.03%]
产前强制性叶酸强化时代妇女妊娠前后低碳水化合物摄入与影响胎儿患神经管缺陷风险的关系研究
Gary M Shaw,Wei Yang
Gary M Shaw
Background: A recent study observed women's restricted carbohydrate diet in the year before conception was associated with increased risk of neural tube defect (NTD)-affected pregnancies. That study corresponded to the er...
Mary J O&#x;Connor,Larissa C Portnoff,Michael Lebsack-Coleman et al.
Mary J O&#x;Connor et al.
Background: The teratogenic effects of prenatal alcohol exposure (PAE) have been extensively documented over the course of 45 years of research and psychiatric problems are pervasive in this population. In adults with PAE...
Clinical Trial
Birth defects research. 2019 Jul 15;111(12):822-828. DOI:10.1002/bdr2.1465 2019
The effects of nifedipine and ivabradine on the functionality of the early rat embryonic heart. Are these drugs a risk in early human pregnancy? [0.03%]
尼卡地平和伊伐布雷在早期大鼠心脏功能中的影响。这些药物会在人类早期妊娠中带来风险吗？
Helen E Ritchie,Carolina Telenius,Elin Gustaffson et al.
Helen E Ritchie et al.
Background: When the human heart begins its earliest contractions from day 21, it lacks a functional autonomic nerve supply. Instead, contractions are generated by regular calcium transients later augmented by the funny c...
Ethanol and cannabinoids interact to alter behavior in a zebrafish fetal alcohol spectrum disorder model [0.03%]
乙醇和大麻素相互作用可改变斑马鱼胎儿酒精谱系障碍模型的行为反应
Oswald Boa-Amponsem,Chengjin Zhang,Somnath Mukhopadhyay et al.
Oswald Boa-Amponsem et al.
Background: Recent work suggests that endocannabinoids (eCBs) may signal through the sonic hedgehog signaling pathway. We therefore hypothesized that combined ethanol and eCB exposure during defined stages of zebrafish em...