Identifying determinants of viral hepatitis and liver cancer care in Michigan Asian American communities through multilevel engagement [0.03%]
通过多层次参与识别密歇根州亚洲美国社区中病毒性肝炎和肝癌护理的决定因素
Parnnate Wongsirisakul,Neehar Parikh,Yi-Chun Wang et al.
Parnnate Wongsirisakul et al.
Background: In Michigan, Asian Americans are disproportionately infected with HBV and HCV. As many infections are first diagnosed when patients present with advanced liver disease or liver cancer, HBV and HCV screening, a...
Electronic decision aids enhance management of primary care patients with steatotic liver disease: Proof of concept pilot study [0.03%]
电子决策辅助工具可提高对脂肪肝患者的管理：概念验证试点研究
Ashley Spann,Kristy Bishop,Sarah Marbach et al.
Ashley Spann et al.
Background: The approach to appropriate risk stratification for metabolic dysfunction-associated steatotic liver disease (MASLD) is variable, and the adoption of non-invasive liver disease assessments in clinical practice...
Evidence that extracellular HSPB1 contributes to inflammation in alcohol-associated hepatitis [0.03%]
外源性HSPB1在酒精相关性肝炎炎症中的作用证据
Anne-Marie C Overstreet,McKenzie Burge,Annette Bellar et al.
Anne-Marie C Overstreet et al.
Background: Alcohol-associated hepatitis (AH) is the most life-threatening form of alcohol-associated liver disease (ALD). AH is characterized by severe inflammation attributed to increased levels of ethanol, microbes or ...
Pathological study of the tumor microenvironment after neoadjuvant therapy in hepatocellular carcinoma: Difference of TACE combined with antiangiogenics and immunotherapy [0.03%]
肝细胞癌新辅助治疗后肿瘤微环境病理学特征研究：TACE联合抗血管生成及免疫治疗的差异性分析
Xintao He,Yanhong Liu,Tianyi Dai et al.
Xintao He et al.
Background: HCC is the leading form of primary liver cancer worldwide. Transcatheter arterial chemoembolization (T) is commonly used to treat unresectable tumors. T combined with antiangiogenic therapy and immunotherapy (...
Fatty acid β-oxidation enhances immune regulatory function of double-negative T cells through pSTAT4-OX40 signaling pathway [0.03%]
脂肪酸β氧化通过pSTAT4-OX40信号通路增强双阴性T细胞的免疫调节功能
Zeyu Wang,Yuan Jiang,Longyang Zhou et al.
Zeyu Wang et al.
Background: Double-negative T (DNT) cells (CD3+CD4-CD8-NK1.1-) demonstrate immunoregulatory functions in maintaining hepatic immune homeostasis. This study investigates how energy metabolism impacts DNT cell survival and ...
Carbon-ion radiotherapy achieves outcomes equivalent to surgical resection for hepatocellular carcinoma [0.03%]
碳离子放疗可实现与手术相当的肝细胞癌疗效
Takeshi Hatanaka,Kei Shibuya,Satoru Kakizaki et al.
Takeshi Hatanaka et al.
Aim: This study aimed to compare the clinical outcomes of carbon-ion radiotherapy (CIRT) to those of surgical resection (SR) in patients with HCC. Methods...
Comparative Study
Hepatology communications. 2025 Aug 29;9(9):e0801. DOI:10.1097/HC9.0000000000000801 2025
Arachidonic acid metabolism in metabolic dysfunction-associated steatotic liver disease and liver fibrosis [0.03%]
代谢功能障碍相关性脂肪肝病和肝纤维化中的花生四烯酸代谢
Yufang Ma,Jingsun Jiang,Chong Zhao et al.
Yufang Ma et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disorder globally, affecting 30% of the population and causing a significant healthcare burden due to its increasing incidence and limited ...
Mediterranean diet and associated metabolite signatures in relation to MASLD progression: A prospective cohort study [0.03%]
地中海饮食及其与MASLD进展相关的代谢标志物谱系的前瞻性队列研究
Kai Wang,Shijian Xiang,Qiangsheng He et al.
Kai Wang et al.
Background: Mediterranean diet (MED) is recommended for managing metabolic dysfunction-associated steatotic liver disease (MASLD). However, associations between MED adherence, related metabolite signatures, and risks of l...
Adipocyte-specific deletion of gp130 prevents ketogenic diet-induced hepatic steatosis [0.03%]
脂肪细胞gp130的特异性缺失可预防生酮饮食诱导的肝脂变
Berkay Senkalfa,Melanie Gloor,Ronja Podlaszewski et al.
Berkay Senkalfa et al.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD), the hepatic manifestation of obesity and type 2 diabetes, can progress to metabolic dysfunction-associated steatohepatitis and fibrosis. MASLD ...
Leukemia inhibitory factor promotes human cholangiopathies, and its inhibition improves cholestasis in Abcb4-/- mice [0.03%]
白细胞介素促进人类胆管疾病及其抑制改善Abcb4-/-小鼠的胆汁淤积
Cristina Di Giorgio,Ginevra Urbani,Carmen Massa et al.
Cristina Di Giorgio et al.
Background: Primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) are immune-mediated cholestatic disorders characterized by progressive biliary inflammation and fibrosis, for which treatment options ...