Simon Haroutounian
Simon Haroutounian
Opioids are among most effective drugs for managing acute postoperative pain. This article discusses the potential effects of perioperative opioids on endocrine and immune function.
Neuropathic pain in leprosy: symptom profile characterization and comparison with neuropathic pain of other etiologies [0.03%]
神经病理性疼痛的症状特征及与其他病因的神经病变性疼痛的比较研究(来自麻风的研究)
Irina Raicher,Patrick Raymond Nicolas Andre Ghislain Stump,Simone Bega Harnik et al.
Irina Raicher et al.
Introduction: Previous studies reported a high prevalence of neuropathic pain in leprosy, being especially present in "pharmacologically cured" patients. The presence of neuropathic pain in leprosy poses a supplementary b...
Reconsidering the International Association for the Study of Pain definition of pain [0.03%]
重新考虑国际疼痛研究协会的痛觉定义
Milton Cohen,John Quintner,Simon van Rysewyk
Milton Cohen
Introduction: The definition of pain promulgated by the International Association for the Study of Pain (IASP) is widely accepted as a pragmatic characterisation of that human experience. Although the Notes that accompany...
Discharge prescription patterns of opioid and nonopioid analgesics after common surgical procedures [0.03%]
常见手术后阿片类和非阿片类止痛药的处方模式
Michael J Nooromid,Eddie Blay Jr,Jane L Holl et al.
Michael J Nooromid et al.
Introduction: Recent literature has shown a wide variation in the prescribing patterns of opioids after elective surgery. We conducted an evaluation of discharge opioid prescribing after elective surgical procedures to de...
Sensory symptom profiles differ between trigeminal and thoracolumbar postherpetic neuralgia [0.03%]
三叉神经后带和胸腰段带状疱疹后神经痛的感觉症状特征不同
Stefanie Rehm,Moritz Groβkopf,Maria Kabelitz et al.
Stefanie Rehm et al.
Introduction: Animal experimental evidence suggests that mechanisms of pain generation and response to treatment differ between neuropathic pain in the cephalic and the extracephalic innervation territories. ...
Specific symptoms may discriminate between fibromyalgia patients with vs without objective test evidence of small-fiber polyneuropathy [0.03%]
特定症状可将纤维肌痛患者与客观检测的小纤维多发性神经病证据区分開来
Mette Lodahl,Roi Treister,Anne Louise Oaklander
Mette Lodahl
Introduction: Multiple studies now confirm that ∼40% of patients with fibromyalgia syndrome meet diagnostic criteria for small-fiber polyneuropathy (SFPN) and have objective pathologic or physiologic evidence of SFPN, wh...
The CGRP receptor antagonist BIBN4096 inhibits prolonged meningeal afferent activation evoked by brief local K+ stimulation but not cortical spreading depression-induced afferent sensitization [0.03%]
CGRP受体拮抗剂BIBN4096抑制了局部K⁺刺激引起的长时间脑膜传入激活,但不能抑制皮质扩散性抑制引起的传入敏化作用
Jun Zhao,Dan Levy
Jun Zhao
Introduction: Cortical spreading depression (CSD) is believed to promote migraine headache by enhancing the activity and mechanosensitivity of trigeminal intracranial meningeal afferents. One putative mechanism underlying...
Post-traumatic stress symptom clusters in acute whiplash associated disorder and their prediction of chronic pain-related disability [0.03%]
急性挥鞭样损伤后压力症状群及其对慢性疼痛相关残疾的预测作用
Annick Maujean,Matthew J Gullo,Tonny Elmose Andersen et al.
Annick Maujean et al.
Introduction: The presence of post-traumatic stress disorder (PTSD) symptoms has been found to be associated with an increased risk of persisting neck pain and disability in motor vehicle crash (MVC) survivors with whipla...
Evidence that dry eye is a comorbid pain condition in a U.S. veteran population [0.03%]
干眼症是美国退伍军人人群共病疼痛状态的证据
Charity J Lee,Roy C Levitt,Elizabeth R Felix et al.
Charity J Lee et al.
Introduction: Recent evidence suggests that dry eye (DE) may be comorbid with other chronic pain conditions. Objectives: To evaluate DE...