3-Nitrotyrosine activates excitatory interneurons by inhibiting GABA receptors in the rat spinal dorsal horn [0.03%]
3-硝基酪氨酸通过抑制大鼠脊髓背角的GABA受体来激活兴奋性中间神经元
Yuta Kaimochi,Manabu Yamanaka,Wataru Taniguchi et al.
Yuta Kaimochi et al.
Introduction: 3-Nitrotyrosine (3-NT) is a stable biomarker formed when reactive nitrogen species (RNS) interact with tyrosine residues. Emerging evidence suggests that RNS can amplify pain and contribute to chronic pain c...
D1 and D2 neurons in medial nucleus accumbens participate in chronic orofacial pain phenotypes [0.03%]
中侧伏隔核的D1和D2神经元参与慢性颌面部疼痛表型
Claudia Daniela Montes-Ángeles,Rey David Andrade-González,Elias Perrusquia-Hernández et al.
Claudia Daniela Montes-Ángeles et al.
Introduction: Trigeminal nerve injuries can lead to different outcomes, such as chronic neuropathic pain. Nevertheless, it is still elusive why different phenotypes of chronic pain development are shown among individuals....
Advancing AI-based clinical decision support for complex interventions requires an operationalized framework [0.03%]
推进基于人工智能的复杂干预措施临床决策支持需要一个操作化框架
Björn Äng,Tony Bohman,Anna Grimby-Ekman et al.
Björn Äng et al.
Predicting high health care use in patients with spinal disorder in secondary care: model development and validation [0.03%]
二次保健中脊柱疾病高医疗需求患者的预测模型构建及验证
Lise Grethe Kjønø,Karin Magnusson,Marianne Bakke Johnsen et al.
Lise Grethe Kjønø et al.
Introduction: Spinal disorders are among the biggest contributors to health care utilization (HCU). Objective: To develop and externall...
Pain medication and nerve injuries in upper or lower limb-a Swedish national registry study [0.03%]
瑞典全国注册研究中的疼痛药物和上肢或下肢神经损伤的关系
Lars B Dahlin,Raquel Perez,Malin Zimmerman et al.
Lars B Dahlin et al.
Introduction: Severe symptoms and disability may remain after upper and lower limb nerve injuries with an additional risk of persistent pain and consumption of pain medication. ...
No significant modulation of pressure pain sensitivity and cardioception after transauricular vagal nerve stimulation [0.03%]
经颅迷走神经刺激后压力痛觉敏感度和心卡压感知无明显改变
Laura Moniek Ronda De Herde,Ken Steffen Frahm,Claus Graff et al.
Laura Moniek Ronda De Herde et al.
Introduction: Transauricular vagal nerve stimulation (taVNS) is gaining interest as a chronic pain treatment due to its convergence with nociceptive pathways. Although pain-modulation by taVNS has been demonstrated, this ...
Childhood maltreatment, trauma, and pain: trauma-related symptoms as mediators in a high-risk group [0.03%]
儿童虐待、创伤和疼痛：高危人群中的创伤相关症状的中介作用
Inga Schalinski,Stine Lehmann,Hanne Klæboe Greger et al.
Inga Schalinski et al.
Introduction: A history of childhood maltreatment (CM) and trauma-related symptoms has been associated with the development of pain conditions. Individuals raised in Residential Youth Care (RYC) often report significant e...
LLMs in Patient-Centric Program Evaluation: Addressing Concerns and Further Considerations [0.03%]
以患者为中心的项目评估中的大语言模型：应对关切和进一步考虑
Kendra H Oliver,Leah Russell Flaherty
Kendra H Oliver
Social determinants of health equity for people with pain: from understanding to action [0.03%]
疼痛人群的健康公平的社会决定因素：从理解到行动
Emily Walker,Emma L Karran,Matthew D Jones et al.
Emily Walker et al.
Objective: This article explores the role of social determinants of health in pain care, highlighting their contribution to health inequities and offering strategies for clinicians to respond to these factors in clinical ...
Clinical pain intensity is associated with greater cannabis demand among people who regularly use cannabis [0.03%]
临床疼痛程度与经常使用大麻者的大麻需求增加有关
Nicholas J Bush,Erin Ferguson,Marco Funez-Ponce et al.
Nicholas J Bush et al.
Objectives: Individuals with pain may engage in pain self-management by using cannabis, increasing the risk of cannabis-related consequences. Past research has demonstrated that the presence of next-day responsibilities s...