Whole-body vibration decreases pain and cartilage degeneration in male and female mice with osteoarthritis [0.03%]
全身振动可减轻骨关节炎小鼠的疼痛和软骨退变
Julia Temp,Melih Özgür Celik,Urszula Zabarylo et al.
Julia Temp et al.
Introduction: Knee osteoarthritis (OA) is a chronic, degenerative joint disorder characterized by cartilage deterioration and persistent pain. Currently, there are no disease-modifying drugs and pharmacological treatments...
Cardiorespiratory fitness and pain severity: Longitudinal associations from the general population-The HUNT study [0.03%]
有氧能力与疼痛严重程度：来自 Hunt 研究队列的纵向关联
Live Førland Havstad,Astrid Woodhouse,Tormod Landmark et al.
Live Førland Havstad et al.
Introduction: Reduced cardiorespiratory fitness (CRF) is associated with chronic pain, but longitudinal population-based evidence is limited. Whether CRF can prevent pain worsening or promote improvement is unclear. ...
Higher disease burden and greater small fibre impairment in women with painful diabetic neuropathy [0.03%]
糖尿病痛性神经病变女性患者更高的疾病负担和更明显的small fiber损伤
Gordon Sloan,Dinesh Selvarajah,Jessica Smith et al.
Gordon Sloan et al.
Objective: Although the incidence of Painful-Diabetic Peripheral Neuropathy (Painful-DPN) is higher in women, the underlying reasons for this are not known. This study investigated sex differences in pain and neurological...
The true experts: codeveloping a preventive psychological intervention for postsurgical pain with patients and caregivers [0.03%]
真正的专家：患者和看护人员共同开发术后止痛的预防性心理干预措施
Jana Hochreuter,Emil Kane Nissen,Cosima Locher et al.
Jana Hochreuter et al.
Introduction: Approximately 20% of youth undergoing major surgery develop chronic postsurgical pain (CPSP). However, preventive interventions for CPSP have yielded mixed results, partly due to the limited involvement of p...
Motor deficits after herpes zoster: a comparative analysis of patient characteristics and sensory changes [0.03%]
带状疱疹后的运动障碍：患者特征和感觉变化的比较分析
Elisabeth J M Adriaansen,Jacqueline F M van Dijk,Bart J H Splinter et al.
Elisabeth J M Adriaansen et al.
Introduction: Herpes zoster (HZ) predominantly affects sensory nerves and can lead to postherpetic neuralgia. A motor deficit in the corresponding myotome is a rare but severe complication. Objectives: The objective of th...
Sleep heart rate predicts next-day pain medication use in posttraumatic stress disorder inpatients [0.03%]
睡眠心率可预测创伤后应激障碍住院患者的次日止痛药使用情况
Gisselle C Tamayo,Ned J Arsenault,Andrea L Jamison et al.
Gisselle C Tamayo et al.
Introduction: Chronic pain and posttraumatic stress disorder (PTSD) are common in Veterans, commonly co-occurring, and are associated with pain medication use. ...
Methylglyoxal alters C-fibre activity-dependent slowing and induces heat hyperalgesia in a sex-dependent manner, in rats [0.03%]
甲基乙二醛以性别依赖的方式改变C纤维的活动依赖性减慢并诱导热过敏反应（以大鼠为模型）
Atanaska N Velichkova,Menekse Mutlu-Smith,Amy L Hall et al.
Atanaska N Velichkova et al.
Introduction: Raised plasma levels of the glycolytic metabolite methylglyoxal are associated with pain symptoms in patients with diabetic neuropathy. Methylglyoxal can regulate the function of NaV1.7 and NaV1.8 ion channe...
Monoclonal antibody inhibition of PAR2 reduces phenotype severity and pain in murine inflammatory bowel disease [0.03%]
抗PAR2单克隆抗体可减轻小鼠炎症性肠病的严重程度和疼痛感
Anne Ritoux,Laura J Grundy,Pravallika Manjappa et al.
Anne Ritoux et al.
Introduction: Abdominal pain is a significant burden for those living with inflammatory bowel disease (IBD), representing a major unmet clinical need due to the scarcity of effective therapeutic options. The G protein-cou...
Electroencephalography during acute painful procedures in neonates: a scoping review [0.03%]
新生儿急性疼痛程序中的脑电图：系统评价
Patricia Y Gunawan,Luke Baxter,Maria M Cobo et al.
Patricia Y Gunawan et al.
Although electroencephalography (EEG) is used to assess neonatal pain in research settings, EEG assessments have not been sufficiently characterized for use as end points to assess the efficacy of analgesics in regulatory-endorsed, industry...
Association of widespread pain and peak alpha frequency cannot be isolated to a single network [0.03%]
广泛性疼痛与峰值alpha频段无法归因于单一网络
Jason Cherin,Natalie McLain,Andrew Schrepf et al.
Jason Cherin et al.
Introduction: Peak alpha frequency (PAF), an electroencephalography measure, has gained interest due to its association to pain-related neural processes in both healthy and clinical populations. In healthy groups, PAF der...