B-cell lymphoma-extra large expression correlated with protein kinase RNA-like ER kinase and ubiquitination signals in the type 1 diabetes mouse model [0.03%]
B细胞淋巴瘤-X大型表达与蛋白质激酶RNA样内质网激酶和泛素信号在1型糖尿病小鼠模型中的关联研究
Yu-Yu Kan,Ying-Shuang Chang,Tzu-Ning Chao et al.
Yu-Yu Kan et al.
Introduction: Diabetes mellitus with pain sensation is referred to as diabetic painful neuropathy (DN). DN development results from endoplasmic reticulum (ER) stress, including the upregulation of ER stress signaling-rela...
Bayesian attenuation of offset analgesia filters out random disturbances in noxious stimuli [0.03%]
Bayesian方法减弱偏置镇痛以过滤有害刺激中的随机干扰现象
Ryota Ishikawa,Michihiro Osumi,Jun Izawa
Ryota Ishikawa
Introduction: Offset analgesia (OA), an endogenous pain inhibition after an abrupt decrease in noxious stimulation, provides a paradigm to study dynamic interaction between ascending and descending pain pathways. Previous...
Pathophysiology of subacromial pain syndrome: contributions of rotator cuff-related factors and pain sensitization [0.03%]
肩峰下疼痛综合征的病理生理学：肩袖相关因素和疼痛敏感化的作用
Takafumi Hattori,Satoshi Ohga,Kazuhiro Shimo et al.
Takafumi Hattori et al.
Introduction: Subacromial pain syndrome (SAPS) is complex and multifactorial condition traditionally attributed to structural abnormalities such as rotator cuff tears and tendinopathy. However, pain severity in SAPS canno...
Clarifying the postsurgical persistent pain after laparoscopic cholecystectomy and the role of intravenous lidocaine [0.03%]
探讨腹腔镜胆囊切除术后慢性疼痛的机制及静脉注射利多卡因的作用
Margarida Abreu-Pires,Carla Cavaleiro,Humberto Machado et al.
Margarida Abreu-Pires et al.
Introduction: Persistent abdominal pain after laparoscopic cholecystectomy (PAPLC) incidence is estimated between 3% and 56%. Data concerning PAPLC intensity and its neuropathic characteristics is scarce, and the role of ...
Sex-specific involvement of calcitonin gene-related peptide signaling for pain in experimental autoimmune encephalomyelitis [0.03%]
补体P物质信号通路在实验性自身免疫性脑脊髓炎中性别特异性地参与疼痛调控
Aislinn D Maguire,Timothy N Friedman,Elyse Willis et al.
Aislinn D Maguire et al.
Introduction: Neuropathic pain (NP) is one of the most devastating and under-managed symptoms of multiple sclerosis (MS). As it stands, NP is a difficult condition to treat, as many commonly used pain therapies are ineffe...
Autistic women report high levels of pain, pain-related anxiety, and pain interference [0.03%]
自闭症女性的疼痛、与疼痛相关的焦虑和干扰程度较高
Nathan W Haid,Michelle D Failla,Alexandra Sturm
Nathan W Haid
Introduction: Evidence suggests autistic adults experience pain in different ways compared with nonautistic people. Autistic adults report greater pain-related anxiety, which is associated with increased pain sensitivity,...
Karolin Teichmüller,Hripsime Galstyan,Lisa M Bas et al.
Karolin Teichmüller et al.
Chronic pain is significantly influenced by social interactions, especially within close relationships. However, it is unclear how exactly partner responses such as solicitousness or empathy, affect pain-related and relationship outcomes. I...
Experimental acute muscle pain and itch induce similar inhibitory effects on corticospinal excitability [0.03%]
实验性急性肌肉疼痛和瘙痒对皮质脊髓兴奋性产生类似的抑制作用
Bolette Harritsø Winther,Lars Arendt-Nielsen,Johanne Bagger Graugaard et al.
Bolette Harritsø Winther et al.
Introduction: Pain and itch provoke different motor behaviors. Pain induces motor inhibition, whereas itch triggers an active scratching response. Acute pain is known to decrease corticospinal excitability, assessed by tr...
Neural correlates underlying high-frequency stimulation-induced secondary hyperalgesia in humans [0.03%]
人类高频电刺激诱导的二级痛觉过敏的相关神经机制
Sophie Clarke,Vishvarani Wanigasekera,Richard Rogers et al.
Sophie Clarke et al.
Introduction: Central sensitisation (CS), a mechanism that contributes to chronic pain, is partly characterised by increased pain responses to noxious stimuli (hyperalgesia). High-frequency electrical stimulation (HFS) of...