Diagnostic reassessment in patients previously diagnosed with childhood-onset epilepsy during the transition to adult care: A retrospective cohort study in a tertiary epilepsy center [0.03%]
三级癫痫中心青少年癫痫患者成人期诊断评估的回顾性队列研究
Tetsuhiro Fukuyama,Masaru Nasuno,Manami Yabe et al.
Tetsuhiro Fukuyama et al.
Objective: To investigate the frequency, predictors, and clinical implications of diagnostic reassessment in patients previously diagnosed with childhood-onset epilepsy during the transition period to adult care at a tert...
Characterizing electroencephalogram dynamics during sedation withdrawal: Insights into cortical recovery following status epilepticus [0.03%]
镇静剂撤药过程中脑电图的动力学特征：复杂部分性癫痫持续状态后大脑皮层恢复的见解
Mathieu Dhoisne,Philippe Derambure,Arnaud Delval et al.
Mathieu Dhoisne et al.
Objective: Characterize electroencephalogram (EEG) dynamics during propofol withdrawal in patients with generalized convulsive status epilepticus (GCSE) and explore their association with functional outcomes. ...
Microstructure imaging in patients undergoing evaluation for epilepsy surgery or low-grade glioma: Clinical utility of a novel diffusion MRI method [0.03%]
一种新型弥散MRI方法在癫痫手术或低级别胶质瘤评估患者中的微结构成像及临床应用价值研究
Irena Grubor,Kristina Serednicka,Cornelia Säll et al.
Irena Grubor et al.
Objective: To investigate a recently developed MRI technique for mapping the Mean Diffusivity of Tissue (MDT), which improves diffusion MRI imaging of the cerebral cortex by reducing partial volume effects from cerebrospi...
What does it mean to live with epilepsy? Burden of illness from the patient perspective [0.03%]
患者的疾病负担是多少？从患者的角度看，患癫痫意味着什么？
Joanne M Wagner,Bhagyashree Oak,Brittany Smith et al.
Joanne M Wagner et al.
Objective: To examine the real-world experience, comorbidities, and mental health of patients with epilepsy (PwE) who are currently receiving antiseizure medication (ASM) treatment. ...
Fenfluramine in SCN1A-related GEFS+: A multicenter observational study on efficacy, EEG improvement, and tolerability [0.03%]
芬氟拉明治疗SCN1A相关GEFS+的多中心观察性研究：有效性、脑电图改善及耐受性分析
Giovanni B Dell&#x;Isola,Alice Muda,Lucio Giordano et al.
Giovanni B Dell&#x;Isola et al.
The SCN1A gene is implicated in a broad spectrum of epilepsy phenotypes, ranging from self-limited genetic epilepsy with febrile seizures plus (GEFS+) to severe developmental and epileptic encephalopathies such as Dravet syndrome (DS). Whil...
Loss of cyclin-dependent kinase-like 5 results in susceptibility to audiogenic seizures in mice [0.03%]
cyclin依赖性激酶样5的丢失使小鼠易患音频诱发性癫痫发作
Jordan Higgins,Samuel Egan,Bilal El-Mansoury et al.
Jordan Higgins et al.
CDKL5 deficiency disorder (CDD) is a severe neurodevelopmental encephalopathy characterized by early-onset, treatment-resistant epilepsy. Mice lacking CDKL5 display several clinically relevant phenotypes, but spontaneous seizures are not co...
Safety of postimplantation MRI with Dixi microdeep electrodes in situ: An in vitro evaluation of MRI-related heating at 1.5T [0.03%]
植入Dixi微深电极后进行MRI的安全性：1.5T下体内MRI相关加热的体外评估
Ruth O&#x;Gorman Tuura,Roger Luechinger,Rahel Heule et al.
Ruth O&#x;Gorman Tuura et al.
Objective: Postimplantation assessment of the position of depth EEG electrodes for intracerebral recordings in patients with refractory focal epilepsy can be performed with MRI or with CT after coregistration to a preimpl...
Kerry W Thompson,Lucie Suchomelova,Claude G Wasterlain
Kerry W Thompson
Neonates have a high incidence of seizures that are frequently difficult to control with conventional first-line anti-seizure medications, which are gamma-aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifol...
Structural brain imaging biomarkers for predicting seizure recurrence after a first unprovoked seizure [0.03%]
首次无诱因癫痫发作后的影像学生物标志物预测癫痫复发
Suyi Ooi,Chris Tailby,Heath R Pardoe et al.
Suyi Ooi et al.
Objectives: Predicting seizure recurrence following a first unprovoked seizure (FUS) remains a significant clinical challenge, especially when routine clinical magnetic resonance imaging (MRI) and EEG do not reveal abnorm...
Out of the lab, into real life: Evaluating at-home EEG self-monitoring [0.03%]
从实验室到现实生活：评估家庭环境下的EEG自我监测
Louis Cousyn,Andrea Biondi,Joel S Winston et al.
Louis Cousyn et al.
Seizure forecasting models require long-term, high-quality data collected in real-life settings using noninvasive or minimally invasive devices, yet, the lack of such systems remains a major barrier to their clinical translation. Here, we a...