Korean University Students' Problematic Alcohol use, Depression, and Non-Suicidal Self-Injury During COVID-19 Lockdown [0.03%]
COVID-19封锁期间韩国大学生的酗酒,抑郁和非自杀性自伤问题
In Hong Kim,Yeo Won Jeong,Hyun Kyeong Park
In Hong Kim
Background: This study investigated depression, problematic alcohol use, and non-suicidal self-injury (NSSI) of university students in Korea during COVID-19 lockdown and evaluated the moderating effect of problematic alco...
Sex Differences in Peritraumatic Inflammatory Cytokines and Steroid Hormones Contribute to Prospective Risk for Nonremitting Posttraumatic Stress Disorder [0.03%]
围创伤期炎症细胞因子和类固醇激素的性别差异有助于前瞻性预测创伤后应激障碍的风险持续存在
Chloe S Lalonde,Yara Mekawi,Kelly F Ethun et al.
Chloe S Lalonde et al.
Women are at higher risk for developing posttraumatic stress disorder (PTSD) compared to men, yet little is known about the biological contributors to this sex difference. One possible mechanism is differential immunological and neuroendocr...
Chronic Stress Weakens Connectivity in the Prefrontal Cortex: Architectural and Molecular Changes [0.03%]
慢性压力会削弱前额叶皮质的连接性:结构和分子的变化
Elizabeth Woo,Lauren H Sansing,Amy F T Arnsten et al.
Elizabeth Woo et al.
Chronic exposure to uncontrollable stress causes loss of spines and dendrites in the prefrontal cortex (PFC), a recently evolved brain region that provides top-down regulation of thought, action, and emotion. PFC neurons generate top-down g...
Increases in Psychological Flexibility Mediate Relationship Between Acute Psychedelic Effects and Decreases in Racial Trauma Symptoms Among People of Color [0.03%]
心理灵活性的提高介导了急性迷幻药效应与有色人种种族创伤症状减轻之间的关系
Alan K Davis,Yitong Xin,Nathan D Sepeda et al.
Alan K Davis et al.
Background: Previous research showed acute psychedelic effects were associated with decreases in racial trauma (RT) symptoms among black, indigenous, and people of color (BIPOC). Among samples comprised primarily of white...
Social Stigma and Suicide in Bangladesh: The Covid-19 has Worsened the Situation [0.03%]
新冠肺炎疫情使情况进一步恶化:面对自杀和社交污名化的 Bangladesh 应对之策
Md Rabiul Islam,Md Jamal Hossain
Md Rabiul Islam
Using Psychedelics With Therapeutic Intent Is Associated With Lower Shame and Complex Trauma Symptoms in Adults With Histories of Child Maltreatment [0.03%]
以治疗为目的使用致幻剂与儿童虐待史成年人的复杂创伤症状和羞愧感较低有关
C J Healy,Kellie Ann Lee,Wendy DAndrea
C J Healy
Background: Child maltreatment negatively affects the formation of internal schemata of self and other during development, leading to negative adaptations in self-concept and social cognition. Clinical reports suggest the...
Chronic Pain is Associated With Reduced Sympathetic Nervous System Reactivity During Simple and Complex Walking Tasks: Potential Cerebral Mechanisms [0.03%]
慢性疼痛与步态任务中的交感神经反应降低有关:潜在的脑机制
Taylor D Yeater,David J Clark,Lorraine Hoyos et al.
Taylor D Yeater et al.
Background: Autonomic dysregulation may lead to blunted sympathetic reactivity in chronic pain states. Autonomic responses are controlled by the central autonomic network (CAN). Little research has examined sympathetic re...
Biomarkers of ketamine's antidepressant effect: a clinical review of genetics, functional connectivity, and neurophysiology [0.03%]
氯胺酮抗抑郁作用的生物标志物:基因、功能连接和神经生理的临床综述
Alexandra A Alario,Mark J Niciu
Alexandra A Alario
Major depressive disorder (MDD) is one of the leading causes of morbidity and all-cause mortality (including suicide) worldwide, and, unfortunately, first-line monoaminergic antidepressants and evidence-based psychotherapies are not effecti...
Emerging Therapeutics Based on the Amino Acid Neurotransmitter System: An Update on the Pharmaceutical Pipeline for Mood Disorders [0.03%]
基于氨基酸神经递质系统的新兴治疗手段:情感障碍药物研发管线的最新进展
Julia Hecking,Pasha A Davoudian,Samuel T Wilkinson
Julia Hecking
Mood disorders represent a pressing public health issue and significant source of disability throughout the world. The classical monoamine hypothesis, while useful in developing improved understanding and clinical treatments, has not fully ...
(Re)contextualizing the Trauma to Prevent or Treat PTSD-Related Hypermnesia [0.03%]
contextualizing创伤以预防或治疗PTSD相关性超忆症
Aline Desmedt
Aline Desmedt
A cardinal feature of Post-traumatic stress-related disorder (PTSD) is a paradoxical memory alteration including both intrusive emotional hypermnesia and declarative/contextual amnesia. Most preclinical, but also numerous clinical, studies ...