Neurophysiological Correlates and Differential Drug Response in Subjects With a Family History of an Alcohol Use Disorder [0.03%]
饮酒障碍家族史受试者的神经生理特征及药物治疗反应差异性研究
Sage M Comstock,Jatin G Vaidya,Mark J Niciu
Sage M Comstock
A family history of an alcohol use disorder (AUD) has been shown to increase one's risk of developing an AUD. Additionally, a positive family history of AUD (family history positive (FHP)) has neurobiological and neuropsychopharmacological ...
Lynn D Selemon,Keith A Young,Dianne A Cruz et al.
Lynn D Selemon et al.
Symptoms of posttraumatic stress disorder include hyperarousal, avoidance of trauma-related stimuli, re-experiencing of trauma, and mood changes. This review focuses on the frontal cortical areas that form crucial links in circuitry pertine...
Social Feedback Modulates Neural Response Associated With Cognitive Bias in Individuals Expressing Anxious Symptoms [0.03%]
社会反馈调节与焦虑症状个体的认知偏差相关的神经反应
Khalil Thompson,Kendrick King,Eddy Nahmias et al.
Khalil Thompson et al.
Background: Social anxiety is characterized by a tendency to overestimate the likelihood of negative outcomes and consequences before, during, and after interpersonal interactions with social partners. Recent evidence sug...
"Does the opioid system block or enhance the antidepressant effects of ketamine?" [0.03%]
阿片受体系统是阻断还是增强氯胺酮的抗抑郁效应？
Sanjay J Mathew,Ana Maria Rivas-Grajales
Sanjay J Mathew
Neurosteroid Levels in the Orbital Frontal Cortex of Subjects with PTSD and Controls: A Preliminary Report [0.03%]
PTSD患者和对照组中眶额皮层神经类固醇水平：初步报告
Dianne A Cruz,Leisa A Glantz,Kara D McGaughey et al.
Dianne A Cruz et al.
Background: Neurosteroids mediate stress signaling and have been implicated in the pathogenesis of post-traumatic stress disorder (PTSD) in both preclinical and clinical studies. Compared to controls, subjects with PTSD e...
A Key Noradrenergic Brainstem-Mesolimbic Circuit: Resilience to Social Stress [0.03%]
关键去肾上腺素脑干-中脑边缘通路：抵抗社交压力
Hongxing Zhang,Dipesh Chaudhury,Yu Ma et al.
Hongxing Zhang et al.
Psychiatric and Interpersonal Correlates of Suicide Ideation in Military Sexual Trauma Survivors: The National Health and Resilience in Veterans Study [0.03%]
退伍军人军队性创伤幸存者的自杀意念的精神病学和人际因素研究：来自全国健康与复原力调查的证据
Lindsey L Monteith,Noelle B Smith,Ryan Holliday et al.
Lindsey L Monteith et al.
Background: Veterans who experience military sexual trauma are at increased risk for experiencing suicidal ideation, suicide attempt, and suicide. Yet few studies have attempted to discern factors that relate to suicidal ...
Sex-Dependent Ketamine Addiction-Like Behavior Profile Following Exposure to Chronic Mild Stress [0.03%]
慢性温和应激暴露后氯胺酮引起的性别依赖的药物滥用行为反应差异
Katherine N Wright,Devin P Hagarty,Caroline E Strong et al.
Katherine N Wright et al.
Background: Ketamine has rapid antidepressant effects and shows great promise as a novel treatment for depression, but its limitations including its abuse potential are poorly understood. Given that the prevalence of depr...
Increased Skin Conductance Response in the Immediate Aftermath of Trauma Predicts PTSD Risk [0.03%]
创伤后的皮肤电导反应增强预示PTSD风险
Rebecca Hinrichs,Sanne Jh van Rooij,Vasiliki Michopoulos et al.
Rebecca Hinrichs et al.
Background: Exposure to a traumatic event leads to posttraumatic stress disorder (PTSD) in 10-20% of exposed individuals. Predictors of risk are needed to target early interventions to those who are most vulnerable. The o...
Salience Network Disruption in U.S. Army Soldiers With Posttraumatic Stress Disorder [0.03%]
PTSD患者的优势脑网络损害
Chadi G Abdallah,Christopher L Averill,Amy E Ramage et al.
Chadi G Abdallah et al.
Background: Better understanding of the neurobiology of posttraumatic stress disorder (PTSD) may be critical to developing novel, effective therapeutics. Here, we conducted a data-driven investigation using a well-establi...