Novel Targets for Fast Antidepressant Responses: Possible Role of Endogenous Neuromodulators [0.03%]
新颖的快速抗抑郁靶点：内源性神经调质的可能作用
Anderson Camargo,Ana Lúcia S Rodrigues
Anderson Camargo
The available medications for the treatment of major depressive disorder have limitations, particularly their limited efficacy, delayed therapeutic effects, and the side effects associated with treatment. These issues highlight the need for...
Cornu Ammonis Changes Are at the Core of Hippocampal Pathology in Depression [0.03%]
角螺形回改变是抑郁症海马病理的核心
Darren Roddy,Veronica O&#x;Keane
Darren Roddy
Commentary on: Roddy DW, Farrell C, Doolin K, Roman E, Tozzi L, Frodl T, O'Keane V, O'Hanlon E. The Hippocampus in Depression: More Than the Sum of Its Parts? Advanced Hippocampal Substructure Segmentation in Depression. Biol Psychiatry. 20...
Structural Plasticity Induced by Ketamine in Human Dopaminergic Neurons as Mechanism Relevant for Treatment-Resistant Depression [0.03%]
氯胺酮诱导的人多巴胺能神经元的结构可塑性在难治性抑郁的发生机制中的作用研究
Ginetta Collo,Laura Cavalleri,Emilio Merlo Pich
Ginetta Collo
The mechanisms underlying the antidepressant effects of ketamine in treatment-resistant depression are only partially understood. Reactivation of neural plasticity in prefrontal cortex has been considered critical in mediating the effects o...
An Open-Label Feasibility Trial Examining the Effectiveness of a Cognitive Training Program, Goal Management Training, in Individuals With Posttraumatic Stress Disorder [0.03%]
评估目标管理训练认知训练项目对患有创伤后应激障碍个体有效性的开放性可行性试验研究
Jenna E Boyd,Charlene O&#x;Connor,Alina Protopopescu et al.
Jenna E Boyd et al.
Background: Posttraumatic stress disorder (PTSD) is associated with dysfunction across multiple cognitive domains including executive functioning, attention, and verbal memory. This dysfunction is associated with negative...
Assessing Post-Traumatic Tonic Immobility Responses: The Scale for Tonic Immobility Occurring Post-Trauma [0.03%]
创伤后静止状态评估量表
Chantelle S Lloyd,Ruth A Lanius,Matthew F Brown et al.
Chantelle S Lloyd et al.
Background: Peri-traumatic tonic immobility has been associated with the development and course of post-traumatic stress disorder. Despite serving as an adaptive late-stage defense response, tonic immobility that continue...
The Innate Alarm System and Subliminal Threat Presentation in Posttraumatic Stress Disorder: Neuroimaging of the Midbrain and Cerebellum [0.03%]
PTSD中的内源性警报系统和前意识威胁呈递：脑干和小脑的影像学研究
Braeden A Terpou,Maria Densmore,Janine Thome et al.
Braeden A Terpou et al.
Background: The innate alarm system, a network of interconnected midbrain, other brainstem, and thalamic structures, serves to rapidly detect stimuli in the environment prior to the onset of conscious awareness. This syst...
Overview of the Molecular Steps in Steroidogenesis of the GABAergic Neurosteroids Allopregnanolone and Pregnanolone [0.03%]
γ-氨基丁酸能神经类固醇别孕烯醇酮和孕烯醇酮生物合成的分子步骤概述
Jennifer J Liang,Ann M Rasmusson
Jennifer J Liang
Allopregnanolone and pregnanolone-neurosteroids synthesized from progesterone in the brain, adrenal gland, ovary and testis-have been implicated in a range of neuropsychiatric conditions including seizure disorders, post-traumatic stress di...
Temporoparietal Junction Functional Connectivity in Early Schizophrenia and Major Depressive Disorder [0.03%]
早期精神分裂症和重度抑郁障碍的大颞上回功能连接研究
Jacob Penner,Elizabeth A Osuch,Betsy Schaefer et al.
Jacob Penner et al.
Background: The temporoparietal junction (TPJ) has been linked to lower-level attentional and higher-level social processing, both of which are affected in schizophrenia (SZ) and major depressive disorder (MDD). We examin...
Default Mode Network Maturation and Environmental Adversities During Childhood [0.03%]
儿童期默认模式网络成熟及环境不利因素的影响
Keila Rebello,Luciana M Moura,Walter H L Pinaya et al.
Keila Rebello et al.
Default mode network (DMN) plays a central role in cognition and brain disorders. It has been shown that adverse environmental conditions impact neurodevelopment, but how these conditions impact in DMN maturation is still poorly understood....
Development of Self-Directedness and Cooperativeness in Relation to Post-Traumatic Stress Disorder Symptom Trajectories After Military Deployment [0.03%]
与军事部署后的创伤后应激障碍症状轨迹相关的自我导向性和合作性的发展
Alieke Reijnen,Elbert Geuze,Rosalie Gorter et al.
Alieke Reijnen et al.
Background: Personality traits, such as the character traits self-directedness and cooperativeness, might play a role in the risk of developing post-traumatic stress disorder (PTSD) after deployment to a combat zone. Howe...