Pretreatment Brain Connectome Fingerprint Predicts Treatment Response in Major Depressive Disorder [0.03%]
基于抑郁发作前大脑连接组指纹预测治疗反应
Siyan Fan,Samaneh Nemati,Teddy J Akiki et al.
Siyan Fan et al.
Background: Major depressive disorder (MDD) treatment is characterized by low remission rate and often involves weeks to months of treatment. Identification of pretreatment biomarkers of response may play a critical role ...
Low Dose Ketamine Infusion for Comorbid Posttraumatic Stress Disorder and Chronic Pain: A Randomized Double-Blind Clinical Trial [0.03%]
小剂量氯胺酮输注联合 usual care 治疗合并 PTSD 的慢性疼痛：一项随机双盲临床试验
Alisher R Dadabayev,Sonalee A Joshi,Mariam H Reda et al.
Alisher R Dadabayev et al.
Objective: To date, treatment options (i.e. psychotherapy, antidepressant medications) for patients with posttraumatic stress disorder (PTSD), are relatively few, and considering their limited efficacy, novel therapies ha...
Ketamine Normalizes the Structural Alterations of Inferior Frontal Gyrus in Depression [0.03%]
氯胺酮可 normalized inferior frontal gyrus的结构异常抑郁症患者中
Dan Dai,Cheryl M Lacadie,Sophie E Holmes et al.
Dan Dai et al.
Background: Ketamine is a novel fast-acting antidepressant. Acute ketamine treatment can reverse microstructure deficits and normalize functional alterations in the brain, but little is known about the impacts of ketamine...
Relationships Between Pain, Life Stress, Sociodemographics, and Cortisol: Contributions of Pain Intensity and Financial Satisfaction [0.03%]
疼痛强度和财务满意度对疼痛、生活压力、社会人口特征和皮质醇关系的贡献
Angela M Mickle,Cynthia Garvan,Chelsea Service et al.
Angela M Mickle et al.
Objective: The relationship between psychosocial stress and chronic pain is bidirectional. An improved understanding regarding the relationships among chronic pain, life stress, and ethnicity/race will inform identificati...
A Pilot Study on Playback Theatre as a Therapeutic Aid after Natural Disasters: Brain Connectivity Mechanisms of Effects on Anxiety [0.03%]
一场关于灾后即兴治疗剧场对焦虑影响的脑部连接机制的试点研究
Sarat Munjuluri,Peter K Bolin,Y T Amy Lin et al.
Sarat Munjuluri et al.
Background: Natural disasters can affect mental health and result in symptoms of depression, anxiety, and post-traumatic stress disorder (PTSD). Playback Theatre (PT) is a form of improvisation where actors play-back pers...
Diabetes-Related Distress and Associated Characteristics in Patients With Type 2 Diabetes in an Urban Primary Care Setting in Greece [0.03%]
希腊城市初级护理环境中2型糖尿病患者的与糖尿病相关的压力及其相关特征
Kyriakos Kintzoglanakis,Paraskevi Vonta,Panagiota Copanitsanou
Kyriakos Kintzoglanakis
Background: Diabetes-related distress (DRD) is a common psychological issue of people living with diabetes. International guidelines advise to take DRD into consideration in diabetes care but evidence for Greece is scarce...
Hippocampal and Amygdalar Volume Changes in Major Depressive Disorder: A Targeted Review and Focus on Stress [0.03%]
主要抑郁症中海马和杏仁核体积的变化：专题回顾及对压力的分析
Mark Nolan,Elena Roman,Anurag Nasa et al.
Mark Nolan et al.
Medial temporal lobe structures have long been implicated in the pathogenesis of major depressive disorder. Although findings of smaller hippocampal and amygdalar volumes are common, inconsistencies remain in the literature. In this targete...
Psychedelic Treatment for Trauma-Related Psychological and Cognitive Impairment Among US Special Operations Forces Veterans [0.03%]
美国特种作战部队退伍军人与创伤相关的心理和认知功能障碍的治疗——采用迷幻药物疗法
Alan K Davis,Lynnette A Averill,Nathan D Sepeda et al.
Alan K Davis et al.
Background: U.S. Special Operations Forces Veterans are at increased risk for a variety of mental health problems and cognitive impairment associated with military service. Current treatments are lacking in effectiveness ...
Heterogeneity and Polygenicity in Psychiatric Disorders: A Genome-Wide Perspective [0.03%]
精神病障碍的异质性和多基因性：全基因组视角
Frank R Wendt,Gita A Pathak,Daniel S Tylee et al.
Frank R Wendt et al.
Genome-wide association studies (GWAS) have been performed for many psychiatric disorders and revealed a complex polygenic architecture linking mental and physical health phenotypes. Psychiatric diagnoses are often heterogeneous, and severa...
Corticosterone Induces Depressive-Like Behavior in Female Peri-Pubescent Rats, but Not in Pre-Pubescent Rats [0.03%]
皮质酮在 peri-pubertal 雌性大鼠中诱导类似抑郁的行为，但在 prepubertal 大鼠中没有此效应
Tyler R Nickle,Erica M Stanley,David S Middlemas
Tyler R Nickle
Background: There are no data on the effect of exogenous corticosterone on depressive-like behavior in juvenile rats. Furthermore, it has not been tested whether the effects of corticosterone in female rats is different b...