The Reward System and Post-Traumatic Stress Disorder: Does Trauma Affect the Way We Interact With Positive Stimuli? [0.03%]
奖赏系统与创伤后应激障碍：创伤会如何影响我们对积极刺激的反应？
Rebecca Seidemann,Or Duek,Ruonan Jia et al.
Rebecca Seidemann et al.
Post-traumatic stress disorder (PTSD) is a highly prevalent disorder and a highly debilitating condition. Although anhedonia is an important construct of the disorder, the relationship between PTSD and reward functioning is still under-rese...
Equine-Assisted Activities and Therapies for Veterans With Posttraumatic Stress Disorder: Current State, Challenges and Future Directions [0.03%]
辅助马术活动和疗法治愈患有创伤后应激障碍的老兵：现状、挑战与未来方向
William R Marchand,Sarah J Andersen,Judy E Smith et al.
William R Marchand et al.
Posttraumatic stress disorder is common among military Veterans. While effective treatments exist, many Veterans either do not engage in treatment or fail to achieve full remission. Thus, there is a need to develop adjunctive complementary ...
The Relative Effects of Prazosin on Individual PTSD Symptoms: Evidence for Pathophysiologically-Related Clustering [0.03%]
氯丙嗪对个体PTSD症状的相对影响：病理生理相关聚类的证据
Rebecca C Hendrickson,Steven P Millard,Kathleen F Pagulayan et al.
Rebecca C Hendrickson et al.
Background: The α1-adrenoreceptor antagonist prazosin has in many but not all studies been found to be effective for PTSD associated nightmares, hyperarousal symptoms, and total symptom severity. The particular efficacy ...
Clara Liao,Alex C Kwan
Clara Liao
Rodent models are an invaluable tool for studying the pathophysiological mechanisms underlying stress and depressive disorders. However, the widely used behavioral assays to measure depressive-like states in rodents have serious limitations...
Psychological Impact of the COVID-19 Pandemic on Frontline Health Care Workers During the Pandemic Surge in New York City [0.03%]
纽约新冠疫情期间第一线医护人员的心理影响
Jordyn H Feingold,Lauren Peccoralo,Chi C Chan et al.
Jordyn H Feingold et al.
Background: This study sought to assess the magnitude of and factors associated with mental health outcomes among frontline health care workers (FHCWs) providing care during the Spring 2020 COVID-19 pandemic surge in New ...
Role of Spirituality in the Management of Major Depression and Stress-Related Disorders [0.03%]
灵性在重度抑郁和压力相关障碍管理中的作用
Sajoy P Varghese,Ori David Florentin,Maju Mathew Koola
Sajoy P Varghese
Pretreatment Brain Connectome Fingerprint Predicts Treatment Response in Major Depressive Disorder [0.03%]
基于抑郁发作前大脑连接组指纹预测治疗反应
Siyan Fan,Samaneh Nemati,Teddy J Akiki et al.
Siyan Fan et al.
Background: Major depressive disorder (MDD) treatment is characterized by low remission rate and often involves weeks to months of treatment. Identification of pretreatment biomarkers of response may play a critical role ...
Low Dose Ketamine Infusion for Comorbid Posttraumatic Stress Disorder and Chronic Pain: A Randomized Double-Blind Clinical Trial [0.03%]
小剂量氯胺酮输注联合 usual care 治疗合并 PTSD 的慢性疼痛：一项随机双盲临床试验
Alisher R Dadabayev,Sonalee A Joshi,Mariam H Reda et al.
Alisher R Dadabayev et al.
Objective: To date, treatment options (i.e. psychotherapy, antidepressant medications) for patients with posttraumatic stress disorder (PTSD), are relatively few, and considering their limited efficacy, novel therapies ha...
Ketamine Normalizes the Structural Alterations of Inferior Frontal Gyrus in Depression [0.03%]
氯胺酮可 normalized inferior frontal gyrus的结构异常抑郁症患者中
Dan Dai,Cheryl M Lacadie,Sophie E Holmes et al.
Dan Dai et al.
Background: Ketamine is a novel fast-acting antidepressant. Acute ketamine treatment can reverse microstructure deficits and normalize functional alterations in the brain, but little is known about the impacts of ketamine...