Annotation of Functions of Sequences of Concern and Its Relevance to the New Biosecurity Regulatory Framework in the United States [0.03%]
关注序列功能注释及其与美国新生物安全监管框架的相关性
Gene D Godbold,Matthew B Scholz
Gene D Godbold
Introduction: Recent regulations from United States Government agencies reshape the screening of synthetic nucleic acids. These take a step away from categorizing hazard on the basis of "bad" taxa and invoke the function ...
Biosecurity Assessments for Emerging Transdisciplinary Biotechnologies: Revisiting Biodefense in an Age of Synthetic Biology [0.03%]
面向跨学科新兴生物技术的生物安全评估——合成生物学时代的生物防御制度改革
Diane DiEuliis,Michael J Imperiale,Kavita M Berger
Diane DiEuliis
Introduction: Rapid advances in biotechnologies and transdisciplinary research are enhancing the ability to perform full-scale engineering of biology, contributing to worldwide efforts to create bioengineered plants, medi...
Sophie Rose,Tessa Alexanian,Max Langenkamp et al.
Sophie Rose et al.
Introduction: Affordable and accurate nucleic acid synthesis is foundational to modern biotechnology, but raises security concerns because it facilitates the construction of pathogens and other potentially dangerous biolo...
Enhancing Gene Synthesis Security: An Updated Framework for Synthetic Nucleic Acid Screening and the Responsible Use of Synthetic Biological Materials [0.03%]
增强基因合成安全性：合成核酸筛选及合成生物学材料负责任使用的更新框架
Curtis Matthew Sharkey,Mariam Lekveishvili,Tricia de la Rosa et al.
Curtis Matthew Sharkey et al.
Introduction: In response to continuous advancements in synthetic biotechnologies and in the availability of synthetic nucleic acids to the biological research community since the publication of the 2010 HHS synthetic dou...
A Methodology for the Assessment and Prioritization of Genetic Biocontainment Technologies for Engineered Microbes [0.03%]
工程微生物遗传控制技术评估与优先级排序的方法论研究
Stephen Payne,Scott Wick,Peter A Carr et al.
Stephen Payne et al.
Introduction: Organisms engineered with synthetic genes and genomes have the potential to play critical roles to address important issues in the environment, human health, and manufacturing. Engineered genetic biocontainm...
Screening State of Play: The Biosecurity Practices of Synthetic DNA Providers [0.03%]
人造DNA供应商的生物安全实践筛查现状
Arianne Kane,Michael T Parker
Arianne Kane
Introduction: Synthetic DNA technology is rapidly emerging as a key driver of innovation in the fields of medicine, biotechnology, and more. But it also poses significant risk, particularly in lowering barriers to the pro...
Biosecurity Risk Assessment for the Use of Artificial Intelligence in Synthetic Biology [0.03%]
合成生物学中使用人工智能的生物安全风险评估
Leyma P De Haro
Leyma P De Haro
Background: The integration of Artificial Intelligence (AI) with synthetic biology is driving unprecedented progress in both fields. However, this integration introduces complex biosecurity challenges. Addressing these co...
Safeguarding Mail-Order DNA Synthesis in the Age of Artificial Intelligence [0.03%]
人工智能时代保障定制合成DNA的安全性
Stephanie Batalis,Caroline Schuerger,Gigi Kwik Gronvall et al.
Stephanie Batalis et al.
Introduction: Artificial intelligence (AI) tools continue to be developed and used within the life sciences. The impact of these tools on the biosecurity landscape surrounding mail-order DNA synthesis and how to address t...
Nicole E Wheeler,Sarah R Carter,Tessa Alexanian et al.
Nicole E Wheeler et al.
Introduction: Nucleic acid synthesis is a powerful tool that has revolutionized the life sciences. However, the misuse of synthetic nucleic acids could pose a serious threat to public health and safety. There is a need fo...
Vaporized Hydrogen Peroxide Decontamination of N95 Respirators in a Dedicated Animal Research Facility for Reuse During a Novel Coronavirus Pandemic [0.03%]
N95口罩专用动物实验设施的过氧化氢蒸汽消毒再利用以应对新型冠状病毒肺炎疫情
F Claire Hankenson,Mark Mauntel,Jamie Willard et al.
F Claire Hankenson et al.
Introduction: During the COVID-19 pandemic, health care systems and safety providers have faced an unprecedented challenge of limited access to personal protective equipment (PPE) to conduct patient and public care. In fe...