Repurposing Success: Real-World Validation of a Novel Cephalosporin Decontamination Protocol Using Chlorine Dioxide and Disc Diffusion Testing [0.03%]
成功转化的验证:使用二氧化氯和纸片扩散试验对新型头孢类抗生素除污染方法的有效性研究
Rhys Tancock-Jones,Sofianos Kyriakidis,Brett Cole et al.
Rhys Tancock-Jones et al.
Introduction: Beta-lactam manufacturing facilities face strict regulatory challenges to repurposing for non-beta-lactam production due to the high risk of cross contamination. This study introduces a novel decontamination...
Necessary, Important, and Room for Improvement: Researcher Perspectives on the Impacts of the Select Agent Regulations on Vaccine Development [0.03%]
必要性、重要性和改进空间:关于选择性生物剂法规对疫苗研发影响的研究人员视角
Shreya K Kalra,Michael T Parker
Shreya K Kalra
Introduction: In the United States, vaccine development is a complicated and multifaceted process governed by a myriad of regulatory authorities and structures. In addition to industry laboratory, clinical, and manufactur...
Inter-tool Analysis of a NIST Dataset for Assessing Baseline Nucleic Acid Sequence Screening [0.03%]
NIST数据集的跨工具分析以评估核酸序列筛查的基线水平
Tyler S Laird,Kevin Flyangolts,Craig Bartling et al.
Tyler S Laird et al.
Introduction: Nucleic acid synthesis is a dual-use technology that can benefit fields such as biology, medicine, and information storage. However, synthetic nucleic acids could also potentially be used negligently and ult...
Risk Mitigation Strategies for Artificial Intelligence-Enabled Self-Driving Laboratories [0.03%]
人工智能驱动的自动驾驶实验室风险缓解策略
Leyma P De Haro
Leyma P De Haro
Introduction: Self-driving laboratories (SDLs) are rapidly transforming the scientific enterprise by integrating artificial intelligence (AI), robotics, and automated experimentation to accelerate discovery with greater s...
Establishing a Laboratory Biorisk Management Assessment Tool for Indonesia [0.03%]
在印度尼西亚建立实验室生物风险管理体系评估工具
Aroem Naroeni,Diah Iskandriati,Tjahjani Mirawati Sudiro et al.
Aroem Naroeni et al.
Introduction: Biosafety and biosecurity principles and practices were introduced to Indonesia over the last two decades, with the Avian influenza outbreak serving as the main catalyst. Both have been implemented in parall...
Implementation of a Biorisk Management System in Armenia for ISO 35001:2019 Certification [0.03%]
亚美尼亚ISO 35001:2019认证生物风险管理体系的实施
Hrant Danelyan,Pertsh Tumanyan
Hrant Danelyan
Introduction: Infectious disease outbreaks present significant public health and economic challenges that continue to persist worldwide. Accidental laboratory release or criminal misuse of infectious agents adds to these ...
More than Skin Deep: Primary Inoculation with Mycobacterium tuberculosis as an Occupational Hazard [0.03%]
深入探讨:结核杆菌初次感染作为职业危害
Sarah J Lange,David W Styren,Lisa A Foster et al.
Sarah J Lange et al.
Background: Sharps injuries pose a significant occupational risk for healthcare and laboratory workers, with hundreds of thousands of incidents reported annually. While protocols for blood-borne pathogens like HIV and hep...
Effective Communication at a High-Containment Facility: How Information Consistency and Sufficiency Affect Knowledge, Risk Perceptions, and Community Preparedness for Potential Biological Hazards [0.03%]
高防护设施内的有效沟通:信息一致性和充分性对生物危害知识、风险知觉和社区准备度的影响
Xiaochen Angela Zhang,Raluca Cozma,Nancy Muturi et al.
Xiaochen Angela Zhang et al.
Introduction: Building on risk communication scholarship, this study examines the effectiveness of communication efforts of the National Bio and Agro-Defense Facility through a survey of community residents living near th...
How Forming a Department-Specific Employee Safety Team Impacted Mitigating Risk and Improving the Safety Culture in an Animal Resources Core Facility [0.03%]
动物资源核心设施成立部门员工安全小组对降低风险和改善安全文化的影响
Sumit Ghosh,Samantha Parsons,Joshua Cano et al.
Sumit Ghosh et al.
Introduction: Laboratory staff working in animal facilities face occupational risks beyond biological and chemical hazards. Organizations working with hazardous agents and animals must protect staff by developing safety p...
Articulating Biosafety Program Activities in the Context of a Simplified Public Health Logic Model [0.03%]
从简化的公共卫生逻辑模型视角阐述生物安全项目活动
Robert J Emery,Scott J Patlovich,Bruce Brown et al.
Robert J Emery et al.
Introduction: Public health logic models divide interventions into three categories: inputs, activities, and outcomes. Similarly, biosafety programs can be described using this same logic model by describing inputs in the...