Biosafety Practices for In Vivo Viral-Mediated Gene Therapy in the Health Care Setting [0.03%]
医疗卫生机构活体病毒介导的基因治疗生物安全实践
Jill E Blind,E Nicole McLeod,Alex Brown et al.
Jill E Blind et al.
Introduction: Gene therapy encompasses a diverse array of genetically engineered products in biomedical research. As novel products continue to gain regulatory approval, institutions will be challenged by translating rese...
2019 Biosafety and Biosecurity Month-Beyond the Lab: Increasing the Visibility of Biosafety and Biosecurity [0.03%]
2019生物安全和生物安保月——走出实验室：提升生物安全和生物安保的知名度
Eric J Rouse,Danielle A Rintala
Eric J Rouse
Viji Vijayan,Benson Ng Beng Sern,Barbara Johnson
Viji Vijayan
Introduction: Spill response procedures are an important aspect of laboratories where infectious materials are handled. The decades-old conventional method of spill cleanup uses paper towels to cover the spill. It require...
Validating Autoclave Cycles for Carcass Disposal in Animal Biosafety Level 2/3 Containment Laboratories [0.03%]
动物生物安全二级和三级实验室尸体处理的高压蒸汽灭菌器程序验证
Rebecca McGirr,Christopher Sample,Leslee Arwood et al.
Rebecca McGirr et al.
Introduction: Animal carcasses differ in composition from other types of solid waste, and through prior testing it was determined that cycle parameters applied to general, solid biohazardous waste did not ensure proper st...
The United States' Regulatory Environment Is Evolving to Accommodate a Coming Boom in Gene Therapy Research [0.03%]
美国的监管环境逐渐适应基因治疗研究热潮带来的各种挑战
Daniel Eisenman
Daniel Eisenman
Introduction: A dramatic increase in the number of clinical trials involving gene-modified cell therapy and gene therapy is taking place. The field is on the verge of a boom, and the regulatory environment is evolving to ...
New National Academies Workshop Report on Developing "Norms" for the Provision of Laboratories in Low-Resource Contexts [0.03%]
关于低资源环境下实验室运行“规范”的国家科学院工作组报告
Frances E Sharples,Micah D Lowenthal
Frances E Sharples
Maren Schniederberend,Benjamin Fontes,Rachel Jeffrey
Maren Schniederberend
Introduction: The number of institutions engaging in research with potentially biohazardous materials has increased, indicating a need for newly formed Institutional Biosafety Committees (IBCs) in the United States and fo...
Developing an In-House Biological Safety Cabinet Certification Program at the University of North Dakota [0.03%]
北达科他大学内部生物安全柜认证项目的建立与发展
Sumit Ghosh,Jeffrey Voigt,Terrance Wynne et al.
Sumit Ghosh et al.
Introduction: Biological safety cabinets (BSCs) are the primary means of containment used in laboratories worldwide. To ensure the proper functioning of BSCs, they need to be certified annually, at a minimum, per National...
The Impact of Air Inflow and Interfering Factors on the Performance of Microbiological Safety Cabinets [0.03%]
气流及干扰因素对生物安全柜微生物学性能的影响研究
Simon Parks,Helen Hookway,Kazunobu Kojima et al.
Simon Parks et al.
Introduction: The operator protection factor (OPF) of four biological safety cabinets (BSCs) has been measured under standard and suboptimal conditions. M...
Biosafety Capacity Building During the COVID-19 Pandemic: Results, Insights, and Lessons Learned from an Online Approach in the Philippines [0.03%]
新冠肺炎疫情期间菲律宾线上生物安全能力建设的成果、启示及经验教训
Rohani Cena-Navarro,Rodel Jonathan Vitor,Reynand Jay Canoy et al.
Rohani Cena-Navarro et al.
Introduction: COVID-19 diagnosis was one of the most pressing needs during the early stages of the pandemic. Its entire procedure has inherent biosafety risks that if not properly managed and mitigated can be life threate...