Military Medicine and Medical Research as a Source of Inspiration and Innovation to Solve National Security and Health Challenges in the 21st Century [0.03%]
21世纪军事医学和医学研究成为解决国家安全与卫生挑战的灵感与创新来源
Nanak S Dhillon,Nayeon Jeon,Umut A Gurkan et al.
Nanak S Dhillon et al.
The history of military medicine and research is rife with examples of novel treatments and new approaches to heal and cure soldiers and others impacted by war's devastation. In the 21st century, new threats, like climate change, are combin...
Immunohematologic Biomarkers in COVID-19: Insights into Pathogenesis, Prognosis, and Prevention [0.03%]
新冠肺炎的免疫血液生物标志物：对发病机制、预后和预防的见解
David R Sweet,Michael L Freeman,David A Zidar
David R Sweet
Coronavirus disease 2019 (COVID-19) has had profound effects on the health of individuals and on healthcare systems worldwide. While healthcare workers on the frontlines have fought to quell multiple waves of infection, the efforts of the l...
A Community-Driven Framework to Prioritize the Use of Donated Human Biological Materials in the Context of HIV Cure-Related Research at the End of Life [0.03%]
一种社区主导的框架：在生命末期优先利用捐赠的人类生物材料进行HIV治愈相关研究
Karine Dubé,Thomas J Villa,Jeff Taylor et al.
Karine Dubé et al.
Initiated in 2017 after extensive community engagement, the Last Gift program enrolls altruistic volunteers willing to donate their cells and tissues at the end of life to allow studies on HIV reservoir dynamics across anatomical sites. As ...
Claudia Jafari,Ioana D Olaru,Franziska Daduna et al.
Claudia Jafari et al.
Introduction: The rapid diagnosis of tuberculosis recurrence can be challenging due to persistently positive detection of Mycobacterium tuberculosis-specific DNA from sputum and bronchopulmonary samples in the absence of ...
Differential CD4+ T-Cell Cytokine and Cytotoxic Responses Between Reactivation and Latent Phases of Herpes Zoster Infection [0.03%]
水痘-带状疱疹感染休眠期和再激活期CD4⁺T细胞细胞因子及细胞毒性反应的差异性研究
Wenjie Jin,Mike Fang,Ismail Sayin et al.
Wenjie Jin et al.
Background: CD4+ T cells are a critical component of effective immune responses to varicella zoster virus (VZV), but their functional properties during the reactivation acute vs latent phase of infection remain poorly def...
HIV-1 is Transported into the Central Nervous System by Trafficking Infected Cells [0.03%]
HIV-1通过转运感染细胞进入中枢神经系统
Laura P Kincer,Gretja Schnell,Ronald Swanstrom et al.
Laura P Kincer et al.
Background: In this work, we carried out a cross-sectional study examining HIV-1 and HCV free virus concentrations in blood and cerebrospinal fluid (CSF) to determine whether HIV-1 enters the central nervous system (CNS) ...
Lauren Grimm,Chinyere Onyeukwu,Grace Kenny et al.
Lauren Grimm et al.
Introduction: Neutralizing antibodies have been shown to develop rapidly following SARS-CoV-2 infection, specifically against spike (S) protein, where cytokine release and production is understood to drive the humoral imm...
Lela Kardava,Clarisa M Buckner,Susan Moir
Lela Kardava
Most vaccines against viral pathogens protect through the acquisition of immunological memory from long-lived plasma cells that produce antibodies and memory B cells that can rapidly respond upon an encounter with the pathogen or its varian...
Evaluation of Interventions to Improve Ventilation in Households to Reduce Risk for Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 [0.03%]
评估改善家庭通风的干预措施以减少严重急性呼吸系统综合征冠状病毒2传播的风险
Wilson Ha,Mitchell A Stiefel,Jeremy R Gries et al.
Wilson Ha et al.
Background: Inadequate ventilation may contribute to the high risk for household transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ...
Pandemics and the English Language: Concepts Critical for Conversing About COVID-19 [0.03%]
大流行与英语：讨论COVID-19所需的关键概念
Neil S Greenspan,Guillermo A Pereda
Neil S Greenspan
We consider the multiple senses of several key terms that are used to discuss the ongoing COVID-19 pandemic and clarify meanings of the corresponding concepts. Topics addressed include: 1) the meaning of immunity to an infectious agent in v...