Time to Think Antifungal Resistance Increased Antifungal Resistance Exacerbates the Burden of Fungal Infections Including Resistant Dermatomycoses [0.03%]
是时候关注抗真菌耐药性了耐药性增加加重了真菌感染的负担，包括耐药皮肤真菌病
Thomas S McCormick,Mahmoud Ghannoum
Thomas S McCormick
Increased antifungal resistance is exacerbating the burden of invasive fungal infections, as well as potentially contributing to the increase in resistant dermatomycoses. In this commentary, we focus on antifungal drug resistance, in contra...
Progress Note 2024: Curing HIV; Not in My Lifetime or Just Around the Corner? [0.03%]
进展报告2024：治愈HIV；是否并非我有生之年就能实现，或者就在不远处？
Justin Harper,Michael R Betts,Mathias Lichterfeld et al.
Justin Harper et al.
Once a death sentence, HIV is now considered a manageable chronic disease due to the development of antiretroviral therapy (ART) regimens with minimal toxicity and a high barrier for genetic resistance. While highly effective in arresting A...
Historical Highlight: The Chemical Characterization of the Pneumococcal Transforming Principle [0.03%]
历史回顾：肺炎链球菌转化因子的化学特征分析
Neil S Greenspan
Neil S Greenspan
HIV Productively Infects Highly Differentiated and Exhausted CD4+ T Cells During AIDS [0.03%]
艾滋病期间HIV感染高度分化和耗竭的CD4+ T细胞
Clayton Faua,Axel Ursenbach,Anne Fuchs et al.
Clayton Faua et al.
Background: Throughout HIV infection, productively infected cells generate billions of viral particles and are thus responsible for body-wide HIV dissemination, but their phenotype during AIDS is unknown. As AIDS is assoc...
Replication and Injury Associated With SARS-CoV-2 in Cultured Hepatocytes [0.03%]
培养的肝细胞中与SARS-CoV-2复制和损伤相关的研究
Suman Pradhan,Susan D Rouster,Jason T Blackard et al.
Suman Pradhan et al.
Background: Liver dysfunction is one of the hallmarks of SARS-CoV-2 infection. The mechanism(s) of hepatic injury in SARS-CoV-2 infection remains controversial with some reporting viral replication and cellular injury and...
Stable Levels of Antibodies Against Unrelated Toxoid Vaccines After COVID-19: COVID-19 Infection Does Not Affect Toxoid Vaccine Antibody Levels [0.03%]
COVID-19感染不影响类毒素疫苗抗体水平：COVID-19感染后对无关类毒素疫苗的抗体水平稳定
Suvi T Jokiranta,Simo Miettinen,Sami Salonen et al.
Suvi T Jokiranta et al.
Background: Lymphopenia is common in COVID-19. This has raised concerns that COVID-19 could affect the immune system akin to measles infection, which causes immune amnesia and a reduction in protective antibodies. ...
Machine Learning Bolsters Evidence That D1, Nef, and Tat Influence HIV Reservoir Dynamics [0.03%]
机器学习增强了对D1, Nef和Tat影响HIV储库动态的证据支持
LaMont Cannon,Sophia Fehrman,Marilia Pinzone et al.
LaMont Cannon et al.
Background: The primary hurdle to curing HIV is due to the establishment of a reservoir early in infection. In an effort to find new treatment strategies, we and others have focused on understanding the selection pressure...
Normospermic Patients Infected With Ureaplasma parvum: Role of Dysregulated miR-122-5p, miR-34c-5, and miR-141-3p [0.03%]
尿素支原体感染的正常精子参数患者：失调的miR-122-5p、miR-34c-5和miR-141-3p的作用
Marilena Galdiero,Carolo Trotta,Maria Teresa Schettino et al.
Marilena Galdiero et al.
Background: Ureaplasma parvum (UP) is a causative agent of non-gonococcal urethritis, involved in the pathogenesis of prostatitis and epididymitis, and it could impair human fertility. Although UP infection is a frequent ...
Arterial Stiffness and Oxidized LDL Independently Associated With Post-Acute Sequalae of SARS-CoV-2 [0.03%]
动脉硬化和氧化LDL与SARS-CoV-2急性后期症状独立相关
Sokratis N Zisis,Jared C Durieux,Christian Mouchati et al.
Sokratis N Zisis et al.
Objective: COVID-19 survivors can experience lingering symptoms known as post-acute sequelae of SARS-CoV-2 (PASC) that appear in different phenotypes, and its etiology remains elusive. We assessed the relationship of endo...
Highlights from the Inaugural HIV Reservoirs and Immune Control Conference, October 1st-4th 2023, Malahide Ireland [0.03%]
首届HIV储库与免疫控制会议亮点（2023年10月1日至4日，爱尔兰马莱德）
Una O&#x;Doherty,Javier Martinez-Picado,Asier Sáez-Cirión
Una O&#x;Doherty
The inaugural FASEB HIV Reservoirs and Immune Control Conference brought researchers together from across the globe to discuss reservoir dynamics in clinical cohorts. It extended over 4 days in the seaside town of Malahide, Ireland. The sci...