People Living With HIV Have More Intact HIV DNA in Circulating CD4+ T Cells if They Have History of Pulmonary Tuberculosis [0.03%]
活动性肺结核病史对人类免疫缺陷病毒完整DNA的影响
Marc Antoine Jean Juste,Yvetot Joseph,Dominique Lespinasse et al.
Marc Antoine Jean Juste et al.
Background: A primary barrier to curing HIV is the HIV reservoir. The leading infectious cause of death worldwide for people living with HIV is tuberculosis (TB), but we do not know how TB impacts the HIV reservoir. ...
Effect of Ceftaroline, Ceftazidime/Avibactam, Ceftolozane/Tazobactam, and Meropenem/Vaborbactam on Establishment of Colonization by Vancomycin-Resistant Enterococci and Klebsiella pneumoniae in Mice [0.03%]
头孢他啶/阿维巴坦、 ceftaroline、 头孢洛扎/他唑巴和美罗培南/维泊酮对小鼠肠球菌和肺炎克雷伯氏菌定植的影响
Bryan S Hausman,Samir Memic,Jennifer L Cadnum et al.
Bryan S Hausman et al.
Background: The potential for promotion of intestinal colonization with healthcare-associated pathogens by new antibiotics used to treat infections due to multidrug-resistant Gram-negative bacilli is unclear. ...
Dr. Anthony Fauci Shares Insights on His Career and Leadership of the NIAID [0.03%]
安东尼福奇分享了他的职业生涯和NIAID领导生涯的见解
Michael M Lederman,Neil S Greenspan
Michael M Lederman
Impact of SARS-CoV-2 Resistance to Antiviral Monoclonal Antibody Therapy on Neutralizing Antibody Response [0.03%]
SARS-CoV-2对抗病毒单克隆抗体治疗的抵抗力对其中和抗体反应的影响
Marc-Kendy Paul,Manish C Choudhary,Amy L Heaps et al.
Marc-Kendy Paul et al.
Background: Anti-SARS-CoV-2 monoclonal antibodies (mAbs) have played a key role as an anti-viral against SARS-CoV-2, but there is a potential for resistance to develop. The interplay between host antibody responses and th...
Sensitivity Analysis of C. auris, S. cerevisiae, and C. cladosporioides by Irradiation with Far-UVC, UVC, and UVB [0.03%]
远UVC、UVC和UVB照射对C.auris，S.cerevisiae和C.cladosporioides的敏感性分析
Anna-Maria Gierke,Martin Hessling
Anna-Maria Gierke
Background: The World Health Organization has published a list of pathogenic fungi with prior-itizing groups and calls for research and development of antifungal measures, with Candida auris belonging to the group with hi...
Comparison Study of the Bio-Plex and Meso Scale Multiplexed SARS-CoV-2 Serology Assays Reveals Evidence of Diminished Host Antibody Responses to SARS-CoV-2 after Monoclonal Antibody Treatment [0.03%]
比较研究Bio-plex和Meso Scale多重SARS-CoV-2血清学检测试剂盒发现单克隆抗体治疗后SARS-CoV-2感染患者的宿主免疫反应减弱现象
Urvi M Parikh,Amy L Heaps,Daniela Moisi et al.
Urvi M Parikh et al.
Background: Assessing the breadth and duration of antigen-specific binding antibodies provides valuable information for evaluating interventions to treat or prevent SARS-CoV-2 infection. Multiplex immunoassays are a conve...
Diagnostic Utility of Pre-Genomic Hepatitis B RNA in the Evaluation of HBV/HIV Coinfection [0.03%]
HBV/HIV共感染评估中HBV前基因组RNA检测的诊断价值分析
Kenneth E Sherman,Susan D Rouster,Heidi Meeds et al.
Kenneth E Sherman et al.
Background: Newer biomarkers of Hepatitis B virus (HBV) infection and treatment response have not been well-characterized in individuals with HBV/HIV coinfection. ...
A Transcriptomic Biomarker Predicting Linezolid-Associated Neuropathy During Treatment of Drug-Resistant Tuberculosis [0.03%]
预测治疗耐药结核病期间利奈唑胺相关神经病变的转录组生物标志物
Nika Zielinski,Dragos Baiceanu,Antonela Dragomir et al.
Nika Zielinski et al.
Background: Neuropathic adverse events occur frequently in linezolid-containing regimens, some of which remain irreversible after drug discontinuation. Ob...
Characteristics and Functions of Infection-enhancing Antibodies to the N-terminal Domain of SARS-CoV-2 [0.03%]
针对SARS-CoV-2 N末端结构域的感染增强型抗体的特性与功能
Ruth I Connor,Mrunal Sakharkar,C Garrett Rappazzo et al.
Ruth I Connor et al.
Background: Fcγ-receptor (FcγR)-independent enhancement of SARS-CoV-2 infection mediated by N-terminal domain (NTD)-binding monoclonal antibodies (mAbs) has been observed in vitro, but the functional significance of the...
The Gut and the Translocated Microbiomes in HIV Infection: Current Concepts and Future Avenues [0.03%]
HIV感染中的肠道及易位菌群：当前概念与未来前景
Krystelle Nganou-Makamdop,Daniel C Douek
Krystelle Nganou-Makamdop
It is widely acknowledged that HIV infection results in disruption of the gut's mucosal integrity partly due a profound loss of gastrointestinal CD4+ T cells that are targets of the virus. In addition, systemic inflammation and immune activ...