Inflammation and Microbial Translocation Correlate with Reduced MAIT Cells in People with HIV [0.03%]
HIV患者中炎症和微生物易位与MAIT细胞减少相关
Angela Ryu,Brian M Clagett,Michael L Freeman
Angela Ryu
Background: Optimal control of microbial infections requires mucosal-associated invariant T (MAIT) cells. People living with HIV (PWH) on antiretroviral therapy (ART) can be divided into 2 groups: immune responders (IR) w...
Historical Highlight: The Luria-Delbrück Fluctuation Test - A Study of the Nature of Bacterial Mutations Conferring Resistance to Infection by Bacteriophage [0.03%]
历史回顾：卢里亚-德尔布吕克波动实验——关于赋予细菌抗噬菌体感染性的突变本质的研究
Neil S Greenspan,Emily N Kukan
Neil S Greenspan
Escape of SARS-CoV-2 Variants KP.1.1, LB.1, and KP3.3 From Approved Monoclonal Antibodies [0.03%]
SARS-CoV-2 变体 KP.1.1、LB.1 和 KP3.3 逃逸 approved 单克隆抗体治疗
Delphine Planas,Isabelle Staropoli,Cyril Planchais et al.
Delphine Planas et al.
Background: First-generation anti-SARS-CoV-2 monoclonal antibodies (mAbs) used for prophylaxis or therapeutic purposes in immunocompromised patients have been withdrawn because of the emergence of resistant Omicron varian...
Jonathan Yewdell Discusses Viral Immunology, Vaccine Development, Navigating a Scientific Career, and Offers Perspectives on Transforming Scientific Publishing and Research Education [0.03%]
乔纳森·耶韦德尔论病毒免疫学、疫苗研发、科研职业发展以及关于转化科学出版物和科研教育的观点
Neil S Greenspan
Neil S Greenspan
In this interview, Jonathan Yewdell talks with Pathogens and Immunity senior editor Neil Green-span about the evolution of viral immunology, highlighting his work and the contributions of other influential scientists. He emphasizes the impo...
People Living With HIV Have More Intact HIV DNA in Circulating CD4+ T Cells if They Have History of Pulmonary Tuberculosis [0.03%]
活动性肺结核病史对人类免疫缺陷病毒完整DNA的影响
Marc Antoine Jean Juste,Yvetot Joseph,Dominique Lespinasse et al.
Marc Antoine Jean Juste et al.
Background: A primary barrier to curing HIV is the HIV reservoir. The leading infectious cause of death worldwide for people living with HIV is tuberculosis (TB), but we do not know how TB impacts the HIV reservoir. ...
Effect of Ceftaroline, Ceftazidime/Avibactam, Ceftolozane/Tazobactam, and Meropenem/Vaborbactam on Establishment of Colonization by Vancomycin-Resistant Enterococci and Klebsiella pneumoniae in Mice [0.03%]
头孢他啶/阿维巴坦、 ceftaroline、 头孢洛扎/他唑巴和美罗培南/维泊酮对小鼠肠球菌和肺炎克雷伯氏菌定植的影响
Bryan S Hausman,Samir Memic,Jennifer L Cadnum et al.
Bryan S Hausman et al.
Background: The potential for promotion of intestinal colonization with healthcare-associated pathogens by new antibiotics used to treat infections due to multidrug-resistant Gram-negative bacilli is unclear. ...
Dr. Anthony Fauci Shares Insights on His Career and Leadership of the NIAID [0.03%]
安东尼福奇分享了他的职业生涯和NIAID领导生涯的见解
Michael M Lederman,Neil S Greenspan
Michael M Lederman
Impact of SARS-CoV-2 Resistance to Antiviral Monoclonal Antibody Therapy on Neutralizing Antibody Response [0.03%]
SARS-CoV-2对抗病毒单克隆抗体治疗的抵抗力对其中和抗体反应的影响
Marc-Kendy Paul,Manish C Choudhary,Amy L Heaps et al.
Marc-Kendy Paul et al.
Background: Anti-SARS-CoV-2 monoclonal antibodies (mAbs) have played a key role as an anti-viral against SARS-CoV-2, but there is a potential for resistance to develop. The interplay between host antibody responses and th...
Sensitivity Analysis of C. auris, S. cerevisiae, and C. cladosporioides by Irradiation with Far-UVC, UVC, and UVB [0.03%]
远UVC、UVC和UVB照射对C.auris，S.cerevisiae和C.cladosporioides的敏感性分析
Anna-Maria Gierke,Martin Hessling
Anna-Maria Gierke
Background: The World Health Organization has published a list of pathogenic fungi with prior-itizing groups and calls for research and development of antifungal measures, with Candida auris belonging to the group with hi...
Comparison Study of the Bio-Plex and Meso Scale Multiplexed SARS-CoV-2 Serology Assays Reveals Evidence of Diminished Host Antibody Responses to SARS-CoV-2 after Monoclonal Antibody Treatment [0.03%]
比较研究Bio-plex和Meso Scale多重SARS-CoV-2血清学检测试剂盒发现单克隆抗体治疗后SARS-CoV-2感染患者的宿主免疫反应减弱现象
Urvi M Parikh,Amy L Heaps,Daniela Moisi et al.
Urvi M Parikh et al.
Background: Assessing the breadth and duration of antigen-specific binding antibodies provides valuable information for evaluating interventions to treat or prevent SARS-CoV-2 infection. Multiplex immunoassays are a conve...