Rosuvastatin Decreases Intestinal Fatty Acid Binding Protein (I-FABP), but Does Not Alter Zonulin or Lipopolysaccharide Binding Protein (LBP) Levels, in HIV-Infected Subjects on Antiretroviral Therapy [0.03%]
rosuvastatin降低肠道脂肪酸结合蛋白（I-FABP），但不影响zonulin或脂多糖结合蛋白（LBP）在抗逆转录病毒治疗的HIV感染者中的水平
Nicholas T Funderburg,Morgan Boucher,Abdus Sattar et al.
Nicholas T Funderburg et al.
Introduction: Altered gastrointestinal (GI) barrier integrity and subsequent microbial translocation may contribute to immune activation in HIV infection. We have reported that rosuvastatin improved several markers of imm...
Netanya S Utay,Daniel C Douek
Netanya S Utay
Whether type I interferons (IFNs) hinder or facilitate HIV disease progression is controversial. Type I IFNs induce the production of restriction factors that protect against mucosal HIV/SIV acquisition and limit virus replication once syst...
Claire Deleage,Stephen W Wietgrefe,Gregory Del Prete et al.
Claire Deleage et al.
A primary obstacle to an HIV-1 cure is long-lived viral reservoirs, which must be eliminated or greatly reduced. Cure strategies have largely focused on monitoring changes in T cell reservoirs in peripheral blood (PB), even though the lymph...
Hepatitis Delta Virus Detected in Salivary Glands of Sjögren's Syndrome Patients and Recapitulates a Sjögren's Syndrome-Like Phenotype in Vivo [0.03%]
在舍格伦综合征患者唾液腺和体内检测到肝 delta 病毒病毒感染及复制
Melodie L Weller,Matthew R Gardener,Zoe C Bogus et al.
Melodie L Weller et al.
Background: Low-level, chronic viral infections have been suspect in the development of select autoimmune diseases, including primary Sjögren's syndrome (pSS). Multiple studies have shown stimulation of antiviral respons...
Addressing Future Epidemics: Historical Human Rights Lessons from the AIDS Pandemic [0.03%]
未来流行病的人权应对——来自艾滋病大流行的启示
Ambar Mehta,Thomas C Quinn
Ambar Mehta
Introduction: The Ebola epidemic in West Africa sparked many ethical and polarizing public health questions on how to adequately control transmission of the virus. These deliberations had and will continue to influence pa...