Use of Dried Blood Spots to Elucidate Full-Length Transmitted/Founder HIV-1 Genomes [0.03%]
用于阐明全长的初始传播HIV-1基因组的干血滴纸检测法的应用
Jesus F Salazar-Gonzalez,Maria G Salazar,Damien C Tully et al.
Jesus F Salazar-Gonzalez et al.
Background: Identification of HIV-1 genomes responsible for establishing clinical infection in newly infected individuals is fundamental to prevention and pathogenesis research. Processing, storage, and transportation of ...
Fluoroquinolone-Resistant Escherichia coli Infections After Transrectal Biopsy of the Prostate in the Veterans Affairs Healthcare System [0.03%]
退伍军人医疗系统中经直肠前列腺活检后氟喹诺酮耐药的大肠埃希菌感染
Elie A Saade,Nuntra Suwantarat,Trina F Zabarsky et al.
Elie A Saade et al.
Background: Recent reports suggest that infections due to fluoroquinolone-resistant Escherichia coli (E. coli) are an increasingly common complication of transrectal biopsy of the prostate (TBP) in the United States. A be...
Epitope Capsid-Incorporation: New Effective Approach for Vaccine Development for Chagas Disease [0.03%]
epitope衣壳结合体的包涵：恰加斯病疫苗开发的新有效途径
Qiana L Matthews,Anitra L Farrow,Girish Rachakonda et al.
Qiana L Matthews et al.
Background: Previously we reported that a hexon-modified adenovirus (Ad) vector containing the invasive neutralizing epitope of Trypanosoma cruzi (T. cruzi) trypomastigote gp83 (Ad5-gp83) provided immunoprotection against...
INTIMATE PARTNER VIOLENCE IS ASSOCIATED WITH INCREASED CD4+ T-CELL ACTIVATION AMONG HIV-NEGATIVE HIGH-RISK WOMEN [0.03%]
伴侣暴力与高风险HIV阴性女性CD4+T细胞活化增加有关
Ameeta S Kalokhe,Chris C Ibegbu,Surinder P Kaur et al.
Ameeta S Kalokhe et al.
Background: Biological pathways mediating the link between intimate partner violence (IPV) and increased HIV risk remain unexplored. We hypothesized that IPV-induced stress negatively affects HIV systemic immune defenses ...
A Cure for HIV Infection: "Not in My Lifetime" or "Just Around the Corner"? [0.03%]
治愈艾滋病：任重道远还是指日可待？
Michael M Lederman,Paula M Cannon,Judith S Currier et al.
Michael M Lederman et al.
With the advent and stunning success of combination antiretroviral therapy (ART) to prolong and improve quality of life for persons with HIV infection, HIV research has been afforded the opportunity to pivot towards studies aimed at finding...
Natural Killer Cell Diversity in Viral Infection: Why and How Much? [0.03%]
病毒感染中的自然杀伤细胞多样性：为什么以及有多少？
Catherine A Blish
Catherine A Blish
Natural killer cells are a diverse group of innate lymphocytes that are specialized to rapidly respond to cancerous or virus-infected cells. NK cell function is controlled by the integration of signals from activating and inhibitory recepto...
Rosuvastatin Decreases Intestinal Fatty Acid Binding Protein (I-FABP), but Does Not Alter Zonulin or Lipopolysaccharide Binding Protein (LBP) Levels, in HIV-Infected Subjects on Antiretroviral Therapy [0.03%]
rosuvastatin降低肠道脂肪酸结合蛋白（I-FABP），但不影响zonulin或脂多糖结合蛋白（LBP）在抗逆转录病毒治疗的HIV感染者中的水平
Nicholas T Funderburg,Morgan Boucher,Abdus Sattar et al.
Nicholas T Funderburg et al.
Introduction: Altered gastrointestinal (GI) barrier integrity and subsequent microbial translocation may contribute to immune activation in HIV infection. We have reported that rosuvastatin improved several markers of imm...
Netanya S Utay,Daniel C Douek
Netanya S Utay
Whether type I interferons (IFNs) hinder or facilitate HIV disease progression is controversial. Type I IFNs induce the production of restriction factors that protect against mucosal HIV/SIV acquisition and limit virus replication once syst...
Claire Deleage,Stephen W Wietgrefe,Gregory Del Prete et al.
Claire Deleage et al.
A primary obstacle to an HIV-1 cure is long-lived viral reservoirs, which must be eliminated or greatly reduced. Cure strategies have largely focused on monitoring changes in T cell reservoirs in peripheral blood (PB), even though the lymph...
Hepatitis Delta Virus Detected in Salivary Glands of Sjögren's Syndrome Patients and Recapitulates a Sjögren's Syndrome-Like Phenotype in Vivo [0.03%]
在舍格伦综合征患者唾液腺和体内检测到肝 delta 病毒病毒感染及复制
Melodie L Weller,Matthew R Gardener,Zoe C Bogus et al.
Melodie L Weller et al.
Background: Low-level, chronic viral infections have been suspect in the development of select autoimmune diseases, including primary Sjögren's syndrome (pSS). Multiple studies have shown stimulation of antiviral respons...