HIV/HCV Co-infection, Liver Disease Progression, and Age-Related IGF-1 Decline [0.03%]
HIV/HCV重叠感染、肝病进展和与年龄相关的IGF-1下降关系研究
Jeffrey Quinn,Jacquie Astemborski,Shruti H Mehta et al.
Jeffrey Quinn et al.
Background: We have previously reported that persons co-infected with HIV and hepatitis C virus (HCV) had liver disease stages similar to HIV-uninfected individuals who were approximately 10 years older. Insulin-like grow...
A Comparison of Molecular Typing Methods Applied to Enterobacter cloacae complex: hsp60 Sequencing, Rep-PCR, and MLST [0.03%]
铜绿假单胞菌复核鉴定方法比较：hsp60测序、Rep-PCR和MLST
Roberto A Viau,Lee M Kiedrowski,Barry N Kreiswirth et al.
Roberto A Viau et al.
Molecular typing using repetitive sequenced-based PCR (rep-PCR) and hsp60 sequencing were applied to a collection of diverse Enterobacter cloacae complex isolates. To determine the most practical method for reference laboratories, we analyz...
European Mitochondrial DNA Haplogroups are Associated with Cerebrospinal Fluid Biomarkers of Inflammation in HIV Infection [0.03%]
欧洲线粒体DNA单倍群与HIV感染的脑脊液炎症标志物相关
David C Samuels,Asha R Kallianpur,Ronald J Ellis et al.
David C Samuels et al.
Background: Mitochondrial DNA (mtDNA) haplogroups are ancestry-related patterns of single-nucleotide polymorphisms that are associated with differential mitochondrial function in model systems, neurodegenerative diseases ...
IMPACT OF TIGECYCLINE VERSUS OTHER ANTIBIOTICS ON THE FECAL METABOLOME AND ON COLONIZATION RESISTANCE TO CLOSTRIDIUM DIFFICILE IN MICE [0.03%]
Tigecycline与其它抗生素对小鼠粪便代谢组及对Clostridium difficile定植抵抗力的影响比较
Robin L P Jump,David Kraft,Kelly Hurless et al.
Robin L P Jump et al.
Background: The glycylcycline antibiotic tigecycline may have a relatively low propensity to promote Clostridium difficile infection in part because it causes less disruption of the indigenous intestinal microbiota than o...
Clinical Application of Interferon-γ Release Assays for the Prevention of Tuberculosis in Countries with Low Incidence [0.03%]
低结核病发病国家干扰素-γ释放试验临床应用以预防结核病
Christoph Lange,Anna M Mandalakas,Barbara Kalsdorf et al.
Christoph Lange et al.
Despite global efforts to control tuberculosis (TB) the estimated number of people who developed TB worldwide increased to an all-time record of more than 10 million in 2015. The goal of the World Health Organization (WHO) to reduce the glo...
"Infectious Supercarelessness" in Discussing Antibiotic-Resistant Bacteria [0.03%]
抗生素抵抗细菌问题上的“传染性大意”现象分析
Neil S Greenspan
Neil S Greenspan
Many bacterial pathogens are exhibiting resistance to increasing numbers of antibiotics making it much more challenging to treat the infections caused by these microbes. In many reports in the media and perhaps even in discussions among phy...
Diminished CD103 (αEβ7) Expression on Resident T Cells from the Female Genital Tract of HIV-Positive Women [0.03%]
HIV阳性女性生殖道驻留T细胞CD103(αEβ7)表达降低
David C Moylan,Paul A Goepfert,Mirjam-Colette Kempf et al.
David C Moylan et al.
Background: Tissue resident memory T cells (TrM) provide an enhanced response against infection at mucosal surfaces, yet their function has not been extensively studied in humans, including the female genital tract (FGT)....
Increasing Rates of Fluoroquinolone Resistance in Escherichia coli Isolated From the Blood and Urine of Patients with Hematologic Malignancies and Stem Cell Transplant Recipients [0.03%]
血液和尿液样本中流感嗜血杆菌分离株的氟喹诺酮耐药率升高：霍奇金淋巴瘤患者及造血干细胞移植受者的感染状况
Christopher G Hauck,Pearlie P Chong,Melissa B Miller et al.
Christopher G Hauck et al.
Fluoroquinolone (FQ) antibiotics have been shown to reduce mortality and the number of febrile episodes when used as prophylaxis during neutropenia. Prior studies suggest that prophylaxis may result in increasing rates of FQ resistance. Flu...
Elevated Circulating Concentrations of Interferon-Gamma in Latent Tuberculosis Infection [0.03%]
潜伏性结核感染患者外周血干扰素-γ水平升高
Moises A Huaman,George S Deepe Jr,Carl J Fichtenbaum
Moises A Huaman
Background: Latent tuberculosis infection (LTBI) has been associated with increased immune activation. We assessed circulating concentrations of interferon-gamma in persons with LTBI. ...
Reconstitution of Peripheral T Cells by Tissue-Derived CCR4+ Central Memory Cells Following HIV-1 Antiretroviral Therapy [0.03%]
抗逆转录病毒治疗后HIV-1外周T细胞由组织衍生的CCR4+中央记忆T细胞重建
Yolanda D Mahnke,Kipper Fletez-Brant,Irini Sereti et al.
Yolanda D Mahnke et al.
Background: Highly active antiretroviral therapy induces clinical benefits to HIV-1 infected individuals, which can be striking in those with progressive disease. Improved survival and decreased incidence of opportunistic...