Long-Term Follow-Up After Fecal Microbiota Transplantation via Freeze-Dried Capsules for Recurrent Clostridioides difficile Infection [0.03%]
口服冻干菌胶囊粪便微生物移植治疗复发性艰难梭菌感染的长期随访研究
Michelle T Hecker,Christian Rosero,Rafael Mendo-Lopez et al.
Michelle T Hecker et al.
Background: Fecal microbiota transplantation (FMT) is a standard therapy for recurrent Clostridioides difficile infection (CDI). Limited information is available on the durability of response after FMT via freeze-dried or...
Three-Month cART Initiated During Primary HIV Does Not Correct the Structural, Immune, and Microbial Abnormalities within the Gastrointestinal Tract [0.03%]
在HIV急性期开始为期三个月的抗逆转录病毒治疗无法矫正胃肠道内的结构、免疫和微生物异常现象
Camilla Tincati,Valeria Bono,Silvia Nozza et al.
Camilla Tincati et al.
Background: HIV infection leads to profound alterations of gut structure, immunity, and microbiome, resulting in immune activation and inflammation, which drive the development of non-infectious comorbidities. The introdu...
An Era Ended, But the Legacy Lingers On: A Personal Reflection on Dr. David Baltimore [0.03%]
一个时代的结束，但遗产犹在——追忆戴维·巴尔的摩博士
Parameswaran Ramakrishnan
Parameswaran Ramakrishnan
Dr. David Baltimore's contributions to modern biology span more than six decades and continue to shape the fields of virology, immunology, biochemistry, and molecular biology. Beyond his landmark discoveries-such as reverse transcriptase an...
Defects in Innate and Intrinsic Immunity in Morocco: A Retrospective Analysis of the Genetic Landscape and Clinical Correlations [0.03%]
摩洛哥先天性和固有免疫缺陷的遗传景观和临床相关性回顾分析
Marwa Refaat,Chaymae Oujane,Abderrahmane Errami et al.
Marwa Refaat et al.
Background: Susceptibility to common infectious diseases is often linked to innate immune deficiencies. Patients may present normal standard immunological profiles but remain highly vulnerable to infections, complicating ...
Efficacy of Rezafungin on Candida albicans Endophthalmitis in a Rabbit Model [0.03%]
雷扎fungin治疗白色念珠菌兔眼内炎的疗效研究
John Saghir,Janet Herrada,Lisa Long et al.
John Saghir et al.
Background: Endophthalmitis, a severe infection of the intraocular tissues that can result in permanent loss of vision if not immediately treated, is often caused by fungi, namely Candida albicans. Treatment options are l...
Meeting Summary for Keystone Symposia on HIV Cure: Antiretroviral Therapy (ART)-Free Control of HIV Infection in Durban, South Africa, 2025 [0.03%]
艾滋病治愈关键石研讨会会议纪要：在南非德班举办的“无抗逆转录病毒治疗(RVT)控制HIV感染”分会，2025年
Kiho Tanaka,Tatenda Jimmy Blessing Chikowore,Steven G Deeks et al.
Kiho Tanaka et al.
Antiretroviral therapy (ART) can effectively control human immunodeficiency virus (HIV) replication; however, lifelong treatment is required due to viral reservoirs, which fuel viral rebound. This necessitates curative interventions that ca...
Stanley Plotkin, MD, Discusses Scientific Progress and the Complexities of Public Health Vaccine Policy [0.03%]
斯坦利·plotkin博士介绍疫苗科学进展及公共卫生政策复杂性
Neil S Greenspan,Michael M Lederman
Neil S Greenspan
Stanley Plotkin, M.D., reflects on his professional journey, describing how formative educational experiences influenced his career. He discusses his contributions to vaccine development, notably for rubella and rotavirus, and shares insigh...
Identification and Quantification by Targeted Metabolomics of Antibiotic-Responsive Urinary Small Phenolic Molecules Derived from the Intestinal Microbiota in Mice [0.03%]
基于目标代谢组学的肠道微生物来源的小酚类物质的鉴定及其定量分析——在小鼠尿液中的抗生物质谱响应分子标识与量化研究
Mark E Obrenovich,George E Jaskiw,Renliang Zhang et al.
Mark E Obrenovich et al.
Background: Urinary levels of small molecules generated by the gut microbiota (GMB) constitute potential biomarkers for the state of the GMB. Such metabolites include numerous small phenolic molecules linked to anaerobic ...
John Perfect Shares Insights on Infectious Diseases, Antifungal Therapy, and Drug Resistance [0.03%]
约翰·珀弗ect分享了关于传染病、抗真菌治疗和药物耐受性的见解
Mahmoud Ghannoum,Robert A Bonomo
Mahmoud Ghannoum
In this engaging interview, Dr. John Perfect reflects on his distinguished career in infectious diseases, focusing on his early scientific interests, his pivotal experiences during the emergence of HIV/AIDS, and his extensive research on fu...
Investigating the Interplay of SARS-CoV-2 RNAemia and Peripheral Inflammation in Platelet Dysfunction During Acute SARS-CoV-2 Infection [0.03%]
SARS-CoV-2 RNA血症与急性SARS-CoV-2感染期间血小板功能障碍的外周炎症之间的相互作用研究
Mariangela Scavone,Roberta Rovito,Claudia Ghali et al.
Mariangela Scavone et al.
Background: Circulating degranulated platelets have been described during acute SARS-CoV-2 infection and associated with COVID-19 complications. This study investigated the relationship between the presence of plasma SARS...