Biomarkers of Cellular Stress Do Not Associate with sCD14 in Progressive HIV and SIV Infections in Vivo [0.03%]
细胞应激的生物标志物不会与进行性HIV和SIV感染中的sCD14相关联
Carol L Vinton,Carly E Starke,Alexandra M Ortiz et al.
Carol L Vinton et al.
Background: Microbial translocation occurs after damage to the structural and/or immunological barrier of the gastrointestinal (GI) tract into circulation. Microbial components that trans-locate from the lumen of the GI t...
Effectiveness of Ultraviolet-C Light and a High-Level Disinfection Cabinet for Decontamination of N95 Respirators [0.03%]
紫外线C和高级消毒柜对N95口罩消毒效果的比较研究
Jennifer L Cadnum,Daniel F Li,Sarah N Redmond et al.
Jennifer L Cadnum et al.
Background: Shortages of personal protective equipment (PPE) including N95 respirators are an urgent concern in the setting of the global COVID-19 pandemic. Decontamination of PPE could be useful to maintain adequate supp...
Conversion and Reversion Rates of Tuberculosis Screening Assays in Patients With Rheumatic Diseases and Negative Baseline Screening Under Long-Term Biologic Treatment [0.03%]
长期接受生物制剂治疗的风湿病患者筛查结果由阴性转阳的比例及其再转归率研究
Konstantinos Thomas,Emilia Hadziyannis,Chrisoula Hatzara et al.
Konstantinos Thomas et al.
Background: To determine the conversion and reversion rates of tuberculosis (TB) screening tests (Tuberculin Skin Test-TST, Interferon Gamma Release Assay-IGRA: T-SPOT.TB) during biologic treatment in patients with rheuma...
Enhanced Immunological Recovery With Early Start of Antiretroviral Therapy During Acute or Early HIV Infection-Results of Italian Network of ACuTe HIV InfectiON (INACTION) Retrospective Study [0.03%]
抗逆转录病毒治疗早期启动可增强急性或近期HIV感染者免疫功能：意大利ACuTe HIV感染网络(INACTION)回顾性研究结果
Antonio Muscatello,Silvia Nozza,Massimiliano Fabbiani et al.
Antonio Muscatello et al.
Background: Viral load peak and immune activation occur shortly after exposure during acute or early HIV infection (AEHI). We aimed to define the benefit of early start of antiretroviral treatment (ART) during AEHI in ter...
Compulsory Immunization Protects Against Infection: What Law and Society Can Do [0.03%]
强制接种预防感染：法律与社会可以做些什么
Maxwell J Mehlman,Michael M Lederman
Maxwell J Mehlman
Since their broad implementation, immunizations have decreased morbidity and mortality due to a number of serious infectious diseases. In recent years, exaggerated concerns about the safety of immunizations have resulted in decreased immuni...
Evidence for Persistent Monocyte and Immune Dysregulation After Prolonged Viral Suppression Despite Normalization of Monocyte Subsets, sCD14 and sCD163 in HIV-Infected Individuals [0.03%]
人免疫缺陷病毒感染者在长期病毒抑制后单核细胞和免疫调节持续异常的证据尽管单核细胞亚群，sCD14和sCD163已恢复正常
Anjana Yadav,Andrew V Kossenkov,Vincent R Knecht et al.
Anjana Yadav et al.
Background: People living with HIV on antiretroviral therapy (HIV/ART) experience excess non-AIDS comorbidities, and also remain at increased risk for certain infections and viral malignancies. Monocytes/macrophages are c...
Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B [0.03%]
DS-Cav1稳定呼吸道合胞病毒B亚型融合糖蛋白的晶体结构和免疫原性
M Gordon Joyce,Amy Bao,Man Chen et al.
M Gordon Joyce et al.
Background: Respiratory syncytial virus (RSV) subtypes, A and B, co-circulate in annual epidemics and alternate in dominance. We have shown that a subtype A RSV fusion (F) glycoprotein, stabilized in its prefusion conform...
Urinary Metabolites of Green Tea as Potential Markers of Colonization Resistance to Pathogenic Gut Bacteria in Mice [0.03%]
小鼠尿液中绿茶代谢产物可作为肠道病原菌定植抵抗的潜在标志物
Mark E Obrenovich,George E Jaskiw,Thriveen Sankar Chittoor Mana et al.
Mark E Obrenovich et al.
Background: The gut microbiome (GMB) generates numerous chemicals that are absorbed systemically and excreted in urine. Antibiotics can disrupt the GMB ecosystem and weaken its resistance to colonization by enteric pathog...
Environmental Contamination with Candida Species in Multiple Hospitals Including a Tertiary Care Hospital with a Candida auris Outbreak [0.03%]
包括一所在发生耳霉菌爆发的三级护理医院在内的多家医院的念珠菌环境污染
Jessica Kumar,Brandon Eilertson,Jennifer L Cadnum et al.
Jessica Kumar et al.
Background: Environmental sources have been implicated as a potential source for exogenous acquisition of Candida species, particularly the emerging multidrug-resistant Candida auris. However, limited information is avail...
Impact of Reduced Fluoroquinolone Use on Clostridioides difficile Infections Resulting From the Fluoroquinolone-Resistant Ribotype 027 Strain in a Veterans Affairs Medical Center [0.03%]
氟喹诺酮类药物使用量下降对退伍军人医疗中心里难辨梭菌027耐药基因型感染的影响
Sarah N Redmond,Sandra Y Silva,Brigid M Wilson et al.
Sarah N Redmond et al.
Background: Fluoroquinolone restriction has been proposed as a control measure for Clostridioides difficile infection (CDI) outbreaks associated with fluoroquinolone-resistant ribotype 027 strains. However, relatively few...