The Structure of the Membrane Protein of SARS-CoV-2 Resembles the Sugar Transporter SemiSWEET [0.03%]
SARS-CoV-2包膜蛋白的结构与糖转运蛋白半SWEET类似
Sunil Thomas
Sunil Thomas
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the disease COVID-19 that has decimated the health and economy of our planet. The virus causes the disease not only in people but...
Temporal Clinical and Laboratory Response to Interleukin-6 Receptor Blockade With Tocilizumab in 89 Hospitalized Patients With COVID-19 Pneumonia [0.03%]
托珠单抗治疗COVID-19肺炎住院患者临床和实验室指标的动态变化研究
Daria S Fomina,Mar&#x;yana A Lysenko,Irina P Beloglazova et al.
Daria S Fomina et al.
Background: Pandemic COVID-19 pneumonia due to SARS-2 is an important cause of morbidity and mortality. Emerging evidence links poor outcomes to an inflammatory cytokine storm. ...
Anisocytosis is Associated With Short-Term Mortality in COVID-19 and May Reflect Proinflammatory Signature in Uninfected Ambulatory Adults [0.03%]
红细胞大小不等与COVID-19的短期死亡率相关，并可能反映未感染门诊成人中的促炎特征
Andrew Hornick,Nour Tashtish,Michael Osnard et al.
Andrew Hornick et al.
Background: Red cell distribution width (RDW), a measure of anisocytosis, is observed in chronic inflammation and is a prognostic marker in critically ill patients without COVID-19, but data in COVID-19 are limited. ...
Direct Acting Antivirals in Hepatitis C-Infected Kidney Transplant Recipients: Associations with Long-term Graft Failure and Patient Mortality [0.03%]
直接抗病毒药物在丙型肝炎感染的肾移植受者中的应用：与长期移植物功能障碍和患者死亡率的关系
Michael R Goetsch,Ashutosh Tamhane,Edgar T Overton et al.
Michael R Goetsch et al.
Background: Direct-acting antiviral (DAA) therapy among hepatitis C virus (HCV)-infected kidney transplant recipients is associated with short-term improvement in protein/creatinine (P/C) ratios, but how HCV cure affects ...
Elena Vasilieva,Sara Gianella,Michael L Freeman
Elena Vasilieva
Cytomegalovirus (CMV), a ubiquitous human pathogen that is never cleared from the host, has long been thought to be relatively innocuous in immunocompetent adults, but causes severe complications including blindness, end-organ disease, and ...
Pharmacological Inhibition of PPARy Boosts HIV Reactivation and Th17 Effector Functions, While Preventing Progeny Virion Release and de novo Infection [0.03%]
PPARy的药理抑制可促进HIV活化和Th17效应功能，同时防止子代病毒释放和新近感染
Delphine Planas,Augustine Fert,Yuwei Zhang et al.
Delphine Planas et al.
The frequency and functions of Th17-polarized CCR6+RORyt+CD4+ T cells are rapidly compromised upon HIV infection and are not restored with long-term viral suppressive antiretroviral therapy (ART). In line with this, Th17 cells represent sel...
Pathogenesis of Aging and Age-related Comorbidities in People with HIV: Highlights from the HIV ACTION Workshop [0.03%]
HIV感染者的老化及年龄相关的并发症的病原：HIV ACTION研讨会亮点
Dana Gabuzda,Beth D Jamieson,Ronald G Collman et al.
Dana Gabuzda et al.
People with HIV (PWH) experience accentuated biological aging, as defined by markers of inflammation, immune dysfunction, and the epigenetic clock. They also have an elevated risk of multiple age-associated comorbidities. To discuss current...
Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2 [0.03%]
紫外线C快速消毒机场安全检查箱评估——SARS-CoV-2时代
Jennifer L Cadnum,Daniel F Li,Lucas D Jones et al.
Jennifer L Cadnum et al.
Background: Contaminated surfaces are a potential source for spread of respiratory viruses including SARS-CoV-2. Ultraviolet-C (UV-C) light is effective against RNA and DNA viruses and could be useful for decontamination ...
Ezequiel Ruiz-Mateos,Eva Poveda,Michael M Lederman
Ezequiel Ruiz-Mateos
In most HIV-infected persons, the natural history of untreated infection is one of sustained viremia, progressive CD4 T cell depletion with resultant morbidity and mortality. The advent of effective combination antiretroviral therapy (ART) ...
Characteristic Temporary Loss of Taste and Olfactory Senses in SARS-CoV-2-positive-Individuals with Mild Symptoms [0.03%]
轻症新冠病毒感染者的嗅觉和味觉的减退现象及其特征性变化
Ricarda M Schmithausen,Manuel Döhla,Heidrun Schöβler et al.
Ricarda M Schmithausen et al.