Kavita Pandey,Shahid Umar
Kavita Pandey
Metagenomic analyses have revealed microbial dysbiosis in the gut of patients with colorectal cancer (CRC). The gut microbiota influences CRC via a variety of mechanisms, including microbial-derived factors such as metabolites or genotoxins...
Recent advances in modeling sleep: from the clinic to society and disease [0.03%]
睡眠建模的最新进展：从临床到社会和疾病的影响
John H Abel,Kimaya Lecamwasam,Melissa A St Hilaire et al.
John H Abel et al.
In the past few decades, advances in understanding sleep-wake neurophysiology have occurred hand-in-hand with advances in mathematical modeling of sleep and wake. In this review, we summarize recent updates in modeling the timing and durati...
Seth D Fortmann,Maria B Grant
Seth D Fortmann
Each day, the retina converts an immense number of photons into chemical signals that are then transported to higher order neural centers for interpretation. This process of photo transduction requires large quantities of cellular energy an...
Akshita B Gopal,Soumyadeep Chakraborty,Pratyush K Padhan et al.
Akshita B Gopal et al.
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has triggered the COVID-19 pandemic. Several factors induce hypoxia in COVID-19. Despite being hypoxic, some SARS-CoV-2-infected individuals do not experience any respir...
Jennifer L Shadrach,Julieta Gomez-Frittelli,Julia A Kaltschmidt
Jennifer L Shadrach
Originally referred to as 'muscle sense', the notion that skeletal muscle held a peripheral sensory function was first described early in the 19th century. Foundational experiments by Sherrington in the early 20th century definitively demon...
Interactions between H. pylori and the Gastric Microbiome: Impact on Gastric Homeostasis and Disease [0.03%]
幽门螺旋杆菌与胃微生态的相互作用及其对胃内环境稳定和疾病的影响
Carolina Serrano,Paul R Harris,Phillip D Smith et al.
Carolina Serrano et al.
Like many seemingly inhospitable environments on our planet, the highly acidic human stomach harbors a diverse bacterial microflora. The best-known member of the human gastric flora, Helicobacter pylori, causes a number of gastric diseases,...
Kathleen E Cullen,Omid A Zobeiri
Kathleen E Cullen
As we actively explore the environment, our motion relative to the world stimulates numerous sensory systems. Notably, proprioceptors provide feedback about body and limb position, while the vestibular system detects and encodes head motion...
Tasting temperature: neural and behavioral responses to thermal stimulation of oral mucosa [0.03%]
味觉与温度：口腔黏膜热刺激的神经和行为反应
Christian H Lemon
Christian H Lemon
Temperature sensation contributes to human enjoyment of foods and beverages. The mouthfeel of warmed foods or drinking ice-cold water on a hot day are respectively pleasant and refreshing. Although historically under-studied for a role in f...
Oscillatory ventilation redux: alternative perspectives on ventilator-induced lung injury in the acute respiratory distress syndrome [0.03%]
间歇性通气重审：急性呼吸窘迫综合征中机械通气致肺损伤的再思考
David W Kaczka
David W Kaczka
For patients with the acute respiratory distress syndrome (ARDS), ventilation strategies that limit end-expiratory derecruitment and end-inspiratory overdistension are the only interventions to have significantly reduced the morbidity and m...
Christopher Versteeg,Raeed H Chowdhury,Lee E Miller
Christopher Versteeg
Much remains unknown about the transformation of proprioceptive afferent input from the periphery to the cortex. Until recently, the only recordings from neurons in the cuneate nucleus (CN) were from anesthetized animals. We are beginning t...