Michael P Lazaropoulos,John W Elrod
Michael P Lazaropoulos
Adverse cardiac remodeling is often precipitated by chronic stress or injury inflicted upon the heart during the progression of cardiovascular diseases. Mitochondria play an important role in the cardiomyocyte response to stress by serving ...
Energy transfer between the mitochondrial network and lipid droplets in insulin resistant skeletal muscle [0.03%]
胰岛素抵抗骨骼肌中的线粒体网络与脂滴之间的能量转移
Hailey A Parry,Brian Glancy
Hailey A Parry
Mitochondria and lipid droplets in the insulin resistant skeletal muscle of type 2 diabetic individuals have both been heavily investigated independently and are characterized by more fragmented, dysfunctional mitochondrial networks and lar...
Brandon Theall,Pilar Alcaide
Brandon Theall
The complex syndrome of heart failure (HF) is characterized by increased left ventricular pressures. Cardiomyocytes increase in size, cardiac fibroblasts transform and make extracellular matrix, and leukocytes infiltrate the cardiac tissue ...
Variation in taste ganglion neuron morphology: insights into taste function and plasticity [0.03%]
味觉神经元形态的差异性：对味觉功能和可塑性的启示
Lisa C Ohman,Robin F Krimm
Lisa C Ohman
Chemical information from food is transduced by cells in the taste bud (taste-transducing cells) and carried to the brain by peripheral taste ganglion neurons. These neurons are thought to act simply as cables without any transformation of ...
The contribution of the cardiomyocyte to tissue inflammation in cardiomyopathies [0.03%]
心肌细胞在心肌病组织炎症中的作用
Van Kim Ninh,Joan Heller Brown
Van Kim Ninh
Cardiac injury triggers an acute immune response that drives tissue healing and remodeling via the activation of compensatory mechanisms. Over time, remodeling and inflammation become chronic and have adverse effects that lead to a depressi...
Eleonora Mezzaroma,Antonio Abbate,Stefano Toldo
Eleonora Mezzaroma
The NACHT, leucine-rich repeat (LRR), and pyrin domain (PYD)-containing protein 3 (NLRP3) inflammasome is a macromolecular structure responsible for the inflammatory response to injury or infection. Several types of heart disease are linked...
Declan G Lyons,Jason Rihel
Declan G Lyons
Research over the last 20 years has firmly established the existence of sleep states across the animal kingdom. Work in non-mammalian animal models such as nematodes, fruit flies, and zebrafish has now uncovered many evolutionarily conserve...
Chris J Dallmann,Pierre Karashchuk,Bingni W Brunton et al.
Chris J Dallmann et al.
Dexterous motor control requires feedback from proprioceptors, internal mechanosensory neurons that sense the body's position and movement. An outstanding question in neuroscience is how diverse proprioceptive feedback signals contribute to...
Nirupa Chaudhari,Stephen D Roper
Nirupa Chaudhari
Indu S Ambudkar,Aldebaran M Hofer
Indu S Ambudkar