Noncoding RNAs in myocardial ischemia/reperfusion injury and repair [0.03%]
非编码RNA在心肌缺血/再灌注损伤与修复中的作用
Mingliang Pan,Zhixin Li,Xiaohong Wang et al.
Mingliang Pan et al.
Myocardial ischemia/reperfusion (I/R) usually triggers a series of molecular and cellular changes, which yield excessive oxidative stress and massive cardiomyocyte death, leading to sterile inflammation, cardiac fibrosis, and, eventually, h...
Vikram Krishnappa Shettigar,Venkata Naga Srikanth Garikipati
Vikram Krishnappa Shettigar
Obesity is a growing problem worldwide, with its pathophysiology being keenly explored. Previously, the noncoding transcriptome was considered transcriptional noise with no functional relevance. However, emerging evidence suggests a critica...
Myometrial leukocytes [0.03%]
子宫肌层白细胞
Johan Siewiera,Adrian Erlebacher
Johan Siewiera
The myometrium, like all tissues, is home to a cadre of different kinds of leukocytes. As with other tissues, these leukocytes are presumed to contribute not only to host defense, but also to tissue remodeling and repair. The contributions ...
The Protective Role of Regular Aerobic Exercise on Vascular Function with Aging [0.03%]
规律有氧运动对血管功能的保护作用随着衰老而产生的变化
Daniel H Craighead,Kaitlin A Freeberg,Douglas R Seals
Daniel H Craighead
Aging is the primary risk factor for cardiovascular diseases (CVD), the leading cause of death in developed and developing societies. Much of this age-associated increase in CVD risk is due to arterial dysfunction, characterized by stiffeni...
Achala Theres P Moncy,Samarjit Das,Hannah R Vasanthi
Achala Theres P Moncy
Exosomes are small extracellular vesicles released by every cell in the human body and can be found in the circulation of almost every biological fluid. They majorly serve as a communication channel between cells. Exosomal microRNAs (miRNAs...
Proteostasis and resilience in the mechanically-stressed vascular endothelium [0.03%]
血管内皮中受力刺激后的蛋白质稳态与复原能力
Adam Keen,Feiran Zhang,John S Reader et al.
Adam Keen et al.
Endothelial homeostasis is a central feature of vascular health. The vascular endothelium is under constant mechanical stress resulting from blood flow and, therefore, requires a high degree of resilience to adapt to stresses and resist dev...
Sex-Specific Effects of Environmental Pollutants on Pulmonary Immune Responses [0.03%]
环境污染物对肺部免疫反应的性别特异性影响
Sylvia S Sanchez,Fenna C M Sillé
Sylvia S Sanchez
Environmental pollutants can adversely impact various physiological processes, affecting systems such as the respiratory and immune systems. Immune responses are influenced by various factors including age, hormonal status, genetic backgrou...
Recent Insights Concerning Autophagy and Endothelial Cell Nitric Oxide Generation [0.03%]
自噬和内皮细胞一氧化氮生成之间关系的新认识
Seul-Ki Park,Jae Min Cho,Sohom Mookherjee et al.
Seul-Ki Park et al.
Although endothelial cell (EC) dysfunction contributes to the etiology of more diseases than any other tissue in the body, EC metabolism is an understudied therapeutic target. Evidence regarding the important role of autophagy in maintainin...
The emerging role of extracellular vesicle RNAs as mediators of cardiometabolic diseases: from pathophysiology to clinical applications [0.03%]
细胞外囊泡RNA作为心脏代谢疾病中介体的新兴角色：从病理生理学到临床应用
Worawan B Limpitikul,Marta Garcia-Contreras,Saumya Das
Worawan B Limpitikul
Cardiometabolic diseases (CMDs) are a leading contributor to worldwide morbidity and mortality. Recent insights into the pathogenesis of CMDs reveal crucial roles of intercellular crosstalk between metabolically active organs and cardiac ce...
V1-bypassing thalamo-cortical visual circuits in blindsight and developmental dyslexia [0.03%]
视皮质视觉环路在盲视和发育性阅读障碍中的作用
Samy Rima,Michael Christoph Schmid
Samy Rima
Vision rests on computations that primarily rely on the parvocellular and magnocellular geniculate relay of retinal signals to V1. Secondary pathways involving superior colliculus, koniocellular lateral geniculate nucleus and pulvinar and t...