Treatment Outcome of metastatic lesions from renal cell carcinoma underGoing Extra-cranial stereotactic body radioTHERapy: The together retrospective study [0.03%]
肾细胞癌转移病灶接受体外立体定向放疗(SBRT)的疗效评估：TOGETHER回顾性研究
Sebastiano Buti,Melissa Bersanelli,Alessandro Viansone et al.
Sebastiano Buti et al.
Objectives: stereotactic body radiation therapy (SBRT) use has increased overtime for the management of metastatic renal cell carcinoma (mRCC) patients, with a likely good control of irradiated lesions. We planned a retro...
A phase I study of weekly doxorubicin and oral topotecan for patients with relapsed or refractory small cell lung cancer (SCLC): A Fred and Pamela Buffet Cancer Center Clinical Trials Network study [0.03%]
多柔比星与拓扑替康联合治疗复发小细胞肺癌的I期临床研究缓冲癌症中心临床试验网络研究
Vinicius Ernani,Rahat Jahan,Lynette M Smith et al.
Vinicius Ernani et al.
Background: Relapsed/refractory small cell lung cancer (SCLC) has a poor prognosis, with no good options. We evaluated a novel combination of topotecan and doxorubicin, providing sequential topoisomerase I and II inhibiti...
Additional bevacizumab in EGFR-mutant lung adenocarcinoma patients who had oligo-progression after the failure of EGFR-TKI: A single-institute retrospective study [0.03%]
EGFR突变型肺腺癌患者一代TKI耐药寡进展人群中再次序贯贝伐珠单抗的疗效观察：单中心回顾性研究
Kosuke Kashiwabara,Shinji Fujii,Shinsuke Tsumura et al.
Kosuke Kashiwabara et al.
Introduction: In EGFR-mutant NSCLC patients with oligo-progression disease (oligo-PD) after the EGFR-TKI failure, additional local ablative therapy (LAT) including stereotactic ablative radiotherapy reportedly extends the...
Phase Ib/II study of hydroxychloroquine in combination with chemotherapy in patients with metastatic non-small cell lung cancer (NSCLC) [0.03%]
羟氯喹联合化疗治疗转移性非小细胞肺癌患者的Ib/II期研究
Jyoti Malhotra,Salma Jabbour,Michelle Orlick et al.
Jyoti Malhotra et al.
Objectives: Activation of cell survival pathways such as autophagy represents a potential resistance mechanism to chemotherapy in NSCLC. Preclinical studies report that autophagy inhibition suppresses lung tumor developme...
Corrected calcium versus ionized calcium measurements for identifying hypercalcemia in patients with multiple myeloma [0.03%]
用 corrected calcium 和离子钙测量诊断多发性骨髓瘤患者的高钙血症
Michael J Buege,Bryan Do,Hans C Lee et al.
Michael J Buege et al.
Background: Dysregulated bone turnover is an important clinical manifestation of multiple myeloma (MM), and 30% of patients present with hypercalcemia. Serum calcium levels are routinely monitored using total calcium meas...
Evaluation of cytotoxic activity of docetaxel loaded gold nanoparticles for lung cancer drug delivery [0.03%]
载多西他赛金纳米颗粒用于肺癌药物递送的细胞毒性评价研究
S Thambiraj,S Shruthi,R Vijayalakshmi et al.
S Thambiraj et al.
The effective use of the gold nanoparticle (AuNPs) conjugated drugs for targeted drug delivery applications is one of the most promising research areas in the field of cancer. Herein, we aimed to establish a nano drug conjugated with doceta...
Association between long-term NSAID use and opioid abuse among patients with breast cancer [0.03%]
长期使用NSAIDs与乳腺癌患者的阿片类药物滥用之间的关系
Nnaemeka E Onyeakusi,Semiu O Gbadamosi,Fahad Mukhtar et al.
Nnaemeka E Onyeakusi et al.
Background: Improving survival rates among patients with breast cancer has been associated with an increase in the prevalence of co-morbidities like cancer-related pain. Opioids are an important component in the managemen...
Remarkable response to a novel ATR inhibitor in a patient with poorly differentiated neuroendocrine carcinoma [0.03%]
一种新型ATR抑制剂治疗分化差的神经内分泌癌的显著疗效
Yoshihito David Saito,Zaibo Li,Maryam Lustberg et al.
Yoshihito David Saito et al.
M6620 (formerly known as VX-970) is a potent inhibitor of ataxia telangiectasia and Rad3-related protein (ATR), a serine/threonine-specific protein kinase involved in activation of checkpoint signaling and promotion of cell cycle arrest in ...
Clinical evaluation of the iXip index to reduce prostate re-biopsies [0.03%]
评估iXip指数以减少前列腺复检活检的临床评价研究
Andrea Benedetto Galosi,Lucio Dell&#x;Atti,Alessandro Bertaccini et al.
Andrea Benedetto Galosi et al.
Background: Prostate biopsy is the gold standard for prostate cancer (PCa) diagnosis, but it's invasive and associated with adverse events. Novel reliable tumor biomarkers and accurate non-invasive tests are required to a...
Mohamed Mabed,Noha Eisa,Shaimaa El-Ashwah et al.
Mohamed Mabed et al.
Introduction: Data regarding clinical characteristics, therapy, maternal and fetal outcomes of pregnancy-associated acute leukemia are limited. Patients a...