Brentuximab vedotin in cutaneous T-Cell lymphoma: emerging evidence and therapeutic insights for CD30-negative and CD30-low disease [0.03%]
布伦妥欣用于皮肤T细胞淋巴瘤：针对CD30阴性和CD30低表达疾病的证据和治疗观点
Renee Morecroft,Jordan Phillipps,Muhamad Alhaj Moustafa
Renee Morecroft
Background: Cutaneous T-cell lymphomas (CTCL) are rare, heterogeneous non-Hodgkin lymphomas primarily involving the skin and are associated with poor outcomes in advanced disease. CD30 expression varies across CTCL subtyp...
Effectiveness of pegylated liposomal doxorubicin (Caelyx®) monotherapy in patients with metastatic HER2-low breast cancer: a monocentric retrospective study [0.03%]
聚乙二醇脂质体多柔比星(Caelyx®)单药治疗HER2低表达转移性乳腺癌患者的疗效：一项单中心回顾性研究
Philippe Boudier,Hervé Bischoff,Laura Somme et al.
Philippe Boudier et al.
Context: Breast cancer (BC) is the most common cancer worldwide, and anthracyclines remain a key component of systemic therapy despite expanding treatment options. A refined HER2 classification has recently emerged, disti...
Association between body mass index and high grade cervical intraepithelial neoplasia (CIN 2/3) in a dysplasia referral population [0.03%]
体重指数与宫颈上皮内瘤变(二三级)的关联性研究
Günther F,Hachenberg J,Stalp J L et al.
Günther F et al.
Background: Obesity is increasingly recognized as a risk factor for several malignancies, including cervical cancer. Women with obesity participate less frequently in screening and may have higher rates of unsatisfactory ...
Incidence of common cancers in Georgia in 2015-2019: A national cancer registry study [0.03%]
格鲁吉亚2015-2019年常见癌症发病情况：一项全国癌症登记队列研究
Ani Beraia,Ariana Znaor,Erik Eik Anda et al.
Ani Beraia et al.
Background: Cancer is the second leading cause of death worldwide, including in Georgia. This study aimed to evaluate the number of new cancer cases, identify the most common cancer sites, analyze sex differences, and eva...
Clinical efficacy and safety of an overall strategy of immunotherapy combined with chemoradiotherapy for limited-stage small cell lung cancer (including induction ± consolidation ± second-line immunotherapy): A propensity score matching study based on real-world data [0.03%]
免疫治疗联合放化疗序贯诱导±巩固±二线免疫疗法治疗局限期小细胞肺癌的临床疗效及安全性：基于真实世界数据的事后倾向性评分匹配分析
Anqi Zhao,Wenlu Chen,Yu Liang et al.
Anqi Zhao et al.
Objective: To compare and analyze the efficacy and safety of an overall strategy of immunotherapy combined with chemoradiotherapy in patients with limited-stage small cell lung cancer (LS-SCLC)-including induction immunot...
Emerging role of interaction between m6A and main ncRNAs in pancreatic cancer [0.03%]
m6A主要ncRNA互作在胰腺癌中的作用机制研究
Xingkai Rui,Jing Gao,Yerui Bi et al.
Xingkai Rui et al.
Pancreatic cancer (PC) is a highly lethal malignancy characterized by its rapid progression and poor prognosis. Despite advancements in understanding its pathogenesis, the intricate interplay of various molecular mechanisms remains to be fu...
Development and pilot feasibility of Kit-CAT, a serious-game-supported consultation for discussing complementary and alternative therapies in breast cancer care [0.03%]
Kit-CAT游戏支持的讨论乳腺癌护理中补充和替代疗法的咨询的发展和试点可行性研究
Nicolas Pinsault,Pauline Girard,Richard Monvoisin et al.
Nicolas Pinsault et al.
Background: Patients with early breast cancer frequently consider complementary therapies, yet structured, ethical discussions remain uncommon. Breast cancer is a particularly relevant context for such discussions because...
EpCAM: A multifunctional protein at the crossroads of cancer biology, diagnosis, and immunotherapy [0.03%]
EpCAM：癌症生物学、诊断和免疫治疗的十字路口上的多功能蛋白
Mehrzad Ghari,Fatemeh Ghaemimanesh
Mehrzad Ghari
The cell surface protein of EpCAM (Epithelial Cell Adhesion Molecule), also known as CD326, is generally expressed in normal epithelia; whereas, its upregulation has been reported in certain tissue stem cells, precursors, and a number of ep...
Investigation of the relationship between autophagy and Warburg effect in osteosarcoma cells: An in vitro study [0.03%]
骨肉瘤细胞自噬与瓦博格效应关系的体外研究
Mehran Molavand,Maryam Majidinia,Amir Valizadeh et al.
Mehran Molavand et al.
Background: This study aims to investigate the interaction between autophagy and the Warburg effect in Saos-2 cells by assessing the effects of 2-deoxyglucose (2-DG) and chloroquine (CQ), alone and combined on cell surviv...
Patient survival outcomes in brain metastases of pancreatic ductal adenocarcinoma: A comprehensive analysis [0.03%]
胰腺导管腺癌脑转移患者的生存结局：全面分析
Yuanchi Ma,Boyang Li,Zhenchao Gao et al.
Yuanchi Ma et al.
Background: Pancreatic ductal adenocarcinoma (PDAC) often presents with metastases. Brain metastases are rare, necessitating a thorough analysis of patient profiles and management. ...