HAVCR2 (TIM-3) as a favorable prognostic immune marker in seminoma: Integrative checkpoint screening and tissue validation [0.03%]
HAVCR2（TIM-3）作为精原细胞瘤有利的预后免疫标志物：综合检查点筛查和组织验证
Ki Hong Kim,Dae Young Lee,Hee Jo Yang et al.
Ki Hong Kim et al.
Background: Immune checkpoint inhibitors targeting the PD-1/PD-L1 axis have demonstrated limited efficacy in testicular germ cell tumors (TGCTs), highlighting the need to identify alternative immune biomarkers. We evaluat...
Dietary fiber and total fat intake density and self-reported cancer history in U.S. adults: NHANES 2021-2022 [0.03%]
2021-2022年美国成年人膳食纤维和总脂肪摄入密度与自报癌症史：NHANES数据分析
Xue Tian,Dongbo Zhang,Yin Jiang et al.
Xue Tian et al.
Background: Diet-cancer associations are often small and sensitive to energy modeling. We tested whether harmonized energy-density exposures yield consistent inferences across design-based and Bayesian approaches in a nat...
The potential of B7-H3 as a new target for CAR-T therapy: Advancements, challenges and clinical perspectives [0.03%]
B7-H3作为新的CAR-T治疗靶点的潜力：进展、挑战及临床前景
Juelan Ye,Jingjing Sun,Jiafeng Hou et al.
Juelan Ye et al.
Malignant tumors remain a major threat to survival and quality of life because of their capacity for recurrence, immune escape, and metastasis. The continuous development of more selective and durable anticancer strategies is therefore a ce...
Efficacy and safety of underwater endoscopic mucosal resection (UEMR) for non-pedunculated colorectal polyps: a prospective study IN Vietnam [0.03%]
越南前瞻性研究：水中内镜黏膜切除术治疗非带蒂结直肠息肉的疗效及安全性
Tran Kinh Thanh,Nguyen Trong Man Dat,Huynh Dao Nhat Huy et al.
Tran Kinh Thanh et al.
Introduction: Colorectal cancer is a leading cause of global malignancy and mortality. While conventional endoscopic mucosal resection (CEMR) is the standard for removing premalignant lesions, it requires submucosal injec...
Clinicopathological features and prognostic factors of pulmonary pleomorphic carcinoma [0.03%]
肺梭形细胞癌的临床病理特征及预后因素分析
Madoka Toyoda,Tetsukan Woo,Tomoe Sawazumi et al.
Madoka Toyoda et al.
Objectives: The objective of this study was to clarify the clinicopathological features and prognostic factors of pulmonary pleomorphic carcinoma (PPC) in a multicenter setting. ...
Management of high-risk biochemical recurrence in prostate cancer: A GCC Delphi consensus (BEAM Panel) [0.03%]
前列腺癌高危生化复发的管理：GCC 德尔菲共识（BEAM 专家组）
Mofarej AlHogbani,Shouki Bazarbashi,Abdullah Alsharm et al.
Mofarej AlHogbani et al.
Background: High-risk biochemical recurrence (HR-BCR) of prostate cancer (PC) is a prostate-specific antigen (PSA)-only relapse state in which rapid PSA kinetics predict early metastatic progression. Variation in care pat...
Characterizing symptom patterns in early-onset colorectal cancer: insights from a national inpatient analysis [0.03%]
基于全国住院研究的早期结直肠癌症状模式特征分析
Ashish Samaddar,Suriya Basker,Sawyer Bawek et al.
Ashish Samaddar et al.
Background: While colorectal cancer (CRC) incidence overall is declining, early-onset CRC (EOCRC, diagnosed before age 50) continues to rise. In response, screening guidelines were lowered from age 50 to 45 in 2021. Howev...
Elevated risks of all-cause mortality and distant metastasis in breast cancer patients with vitamin D deficiency: a population-based analysis [0.03%]
维生素D缺乏乳腺癌患者的全因死亡率和远处转移的危险性增加：基于人口的分析
Yu-Chieh Chen,Ya-Chieh Chang,Chien-Lin Lu et al.
Yu-Chieh Chen et al.
Purpose: Vitamin D plays a key role in immune and cellular regulation, and its deficiency may worsen breast cancer outcomes. This study investigates how serum 25-hydroxyvitamin D levels relate to mortality and metastasis ...
Histone methylation machinery in gliomas: From enzymatic mechanisms to inhibitor development [0.03%]
组蛋白甲基化在胶质瘤中的机制研究及抑制剂开发
Xiaoran Wang,Wenqi Liu,Jie Sun et al.
Xiaoran Wang et al.
Glioma is the most common primary malignant tumor of the central nervous system (CNS). Advances in molecular pathology have established a robust causal link between histone modifications and glioma genesis. In addition to prior findings, re...
Real-world testing practices, treatment patterns, and outcomes of tyrosine kinase inhibitors (TKIs) in epidermal growth factor receptor-mutated advanced/metastatic non-small cell lung cancer: An international study [0.03%]
表皮生长因子受体突变的晚期/转移性非小细胞肺癌的真实世界测试实践、治疗模式和酪氨酸激酶抑制剂（TKI）结局：一项国际研究
Jens Samol,Ingel Demedts,Mustafa Erman et al.
Jens Samol et al.
Objectives: To describe epidermal growth factor receptor (EGFR) mutation (EGFRm) testing practices and treatment patterns in EGFRm-positive patients with advanced/metastatic non-small cell lung cancer (NSCLC) and evaluate...