Routine brain MRI in suspected lung cancer: clinical justification and diagnostic yield [0.03%]
疑似肺癌患者的常规脑MRI检查：临床依据和诊断收益
Camilla Hviid,Christian B Laursen,Pia Iben Pietersen et al.
Camilla Hviid et al.
Background: Lung cancer is the leading cause of cancer-related death worldwide. Brain metastases are common and associated with poor prognosis. While MRI is highly sensitive for detecting brain metastases, the clinical va...
Yield of repeat gastric biopsies and Helicobacter pylori serological assessment in Lynch syndrome [0.03%]
利氏综合症患者胃活检及幽门螺旋杆菌血清学评估的阳性率
Jessica Vadaketh,Jake Konigsberg,Omar Elghawy et al.
Jessica Vadaketh et al.
Background: Upper gastrointestinal surveillance in Lynch syndrome (LS) remains an ongoing debate; some guidelines recommend upper endoscopy with non-targeted biopsies of the gastric antrum/body to detect Helicobacter pylo...
Impact of spleen volume and volume change in non-Hodgkin lymphoma treated with chimeric antigen receptor t-cell therapy [0.03%]
CAR-T细胞治疗非霍奇金淋巴瘤患者的脾脏体积变化及其影响研究
Christina Quell,Wolfgang G Kunz,Viktoria Blumenberg et al.
Christina Quell et al.
Purpose: Chimeric antigen receptor T-cell (CART) therapy targeting CD19 is effective for relapsed/refractory (r/r) lymphoma. As part of the lymphatic system, the spleen might influence CART outcomes. We examined how splee...
Favourable long-term outcomes in selected HER2-Positive early breast cancer patients without pathological complete response after neoadjuvant chemotherapy and trastuzumab: A pre-T-DM1 era cohort study [0.03%]
新辅助化疗和曲妥珠单抗治疗后未达病理完全缓解的部分HER2阳性早期乳腺癌患者的长期预后良好：一项T-DM1时代前队列研究
Ludovic Doucet,Camille Moreau-Bachelard,Laurent Mathiot et al.
Ludovic Doucet et al.
Background: Adjuvant trastuzumab emtansine (T-DM1) is the standard treatment for HER2-positive early breast cancer (EBC) patients who do not achieve a pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC...
The impact of metformin use on survival outcomes in colorectal cancer: A systematic review and meta-analysis [0.03%]
二甲双胍用于结直肠癌的治疗对患者生存期影响的系统评价和 Meta 分析
Mohammad Rahmanian,Iman Elahi Vahed,Mohammad Shirali et al.
Mohammad Rahmanian et al.
Background: Emerging research indicates that metformin exerts anticancer activity across multiple malignancies, including colorectal cancer (CRC). Yet, its prognostic influence in CRC remains uncertain due to conflicting ...
Pro-apoptotic effects of metformin and cisplatin in non-small cell Lung Cancer: Modulation of apoptosis-related genes and LncRNAs [0.03%]
二甲双胍和顺铂对非小细胞肺癌的促凋亡作用：凋亡相关基因和长链非编码RNA的调控
Nazanin Sadeghi,Fatemeh Soleimanifar,Elmira Attar et al.
Nazanin Sadeghi et al.
Background: Lung cancer is a leading cause of cancer-related mortality. While cisplatin is a cornerstone of chemotherapy, metformin (Glucophage) has shown anti-cancer potential. This study investigated the effects of cisp...
Understanding Patient and Oncologist Preferences in the Management of Metastatic Renal Cell Carcinoma [0.03%]
转移性肾细胞癌的患者和肿瘤学医生的治疗偏好分析
Omid Yazdanpanah,Aditya Mahadevan,David J Benjamin et al.
Omid Yazdanpanah et al.
Introduction: Treatment of metastatic renal cell carcinoma (mRCC) has expanded with development of combination therapies containing tyrosine kinase inhibitors (TKIs) with immune checkpoint inhibitors (ICI) agents or dual ...
Nouf Khalifa ALaqeel
Nouf Khalifa ALaqeel
Immunotherapy is currently one of the most promising fields for novel cancer treatments and discoveries. Scientists now understand how intricately our immune system interacts with cancer. The way we think about and treat cancer is evolving ...
Drug-related problems in pediatric, adult and geriatric cancer patients: A systematic review [0.03%]
儿科、成人及老年癌症患者的相关药物问题：一项系统性综述
Ian Osoro,Shribhavana Jawahar,Akila Murugan et al.
Ian Osoro et al.
Background and aim: Drug-related problems (DRPs) are common in cancer treatment due to several reasons, including high doses of drugs and multiple medications. This study aimed to estimate the prevalence of DRPs and to ev...
Somatic gene mutations and their association with treatment outcomes among Indo-Asian Lung Cancer patients [0.03%]
南亚肺癌患者体细胞基因突变及与治疗结果的关联性分析
Safeena Kulsum,Anuja Pradhan,Pragnya Coca et al.
Safeena Kulsum et al.
Background: Insight on genetic mutation has essentially helped clinicians in determining treatment outcomes in lung cancer (LC) due to precision and personalized approach. This study evaluates the mutation trends, treatme...