Clinical and molecular characteristics of 42 Danish patients with metastatic ALK fusion-positive lung cancer treated with first-line alectinib: A nationwide study [0.03%]
丹麦ALK融合阳性转移性肺癌患者接受一线艾乐替尼治疗的临床和分子特征全国性研究（42例）
Maiken Parm Ulhøi,Emma Roger Andersen,Christoffer Trier Maansson et al.
Maiken Parm Ulhøi et al.
Purpose: We investigated whether EML4-ALK fusions and mutations in pre-treatment plasma ctDNA predicted time to treatment discontinuation (TTD) in ALK-positive non-small cell lung cancer (ALK+ NSCLC) patients initiating f...
Prognostic significance of lepidic component in invasive non-mucinous adenocarcinoma of the lung [0.03%]
肺非黏液性浸润性腺癌的鳞状生长方式成分的预后意义
Hironori Ishida,Yoshihiko Shimizu,Tetsuya Umesaki et al.
Hironori Ishida et al.
Objectives: Although radiologic ground-glass opacity (GGO) components are associated with favorable prognosis, limited evidence supports the prognostic significance of corresponding histologic lepidic components. This stu...
A randomized controlled trial comparing large versus small stitch incision closure in gynaecological malignancies (CLaSSIC Study) [0.03%]
妇科恶性肿瘤大切口与小切口缝合的随机对照研究（CLaSSIC研究）
Priya Bhati,Monal Garg,Saumya Gupta et al.
Priya Bhati et al.
Objective: The study aimed to compare Small Stitch Closure (SSC) and Large Stitch Closure (LSC) techniques for reducing incisional ventral hernia (IVH) and surgical site infection (SSI) rates in gynaecological malignancie...
Mobina Tabibian,Elahe Motevaseli,Soudeh Ghafouri-Fard
Mobina Tabibian
Lung cancer is among the most common cancers and the leading source of cancer death. Inhibition of EGFR signaling by small-molecule tyrosine kinase inhibitors and monoclonal antibodies has provided new opportunities for treatment of this ty...
A characterization of the reversibly electroporated penumbra during irreversible electroporation [0.03%]
不可逆电穿孔期间可逆电穿孔半影的特征描述
Rasmus Virenfeldt Flak,Jonatan Riber Granborg,Christian Janfelt et al.
Rasmus Virenfeldt Flak et al.
Background: Irreversible electroporation (IRE) is a novel anticancer ablative treatment, which has been proposed to enhance the efficacy of chemotherapy in the periphery of the ablated area by capturing chemotherapy intra...
Advancements in nasopharyngeal carcinoma radiotherapy: Dosimetric evaluation of arc therapy with hippocampal sparing [0.03%]
鼻咽癌放射治疗进展：弧形放疗联合海马保护的剂量学评估
Fadila Kouhen,Malak Chahid,Hanae El Gouache et al.
Fadila Kouhen et al.
Background: Nasopharyngeal carcinoma (NPC) is located near critical structures like the hippocampus, essential for memory and cognitive function. While Volumetric Modulated Arc Therapy (VMAT) has improved dose conformity ...
Establishment and characterization of patient-derived xenograft of scrotal Paget's disease [0.03%]
阴囊Paget病患者来源异种移植体的建立和特征分析
Xiongbing Lu,Ke Chen,Jiaqi Mei et al.
Xiongbing Lu et al.
Objective: To develop a patient-derived xenograft model (PDX) of Scrotal Paget's disease (SPD), providing an experimental tool for the screening of therapeutic drugs and the development of new drugs for SPD treatment. ...
Improving fertility preservation for male cancer patients: A scoping review of barriers and facilitators [0.03%]
改善癌症患者生育力保存的障碍和促进因素：综述研究
Ariana Orlić,Issam Alsamara,Martina Paric
Ariana Orlić
Background: Fertility preservation (FP) is an important aspect of cancer care for male patients of reproductive age; however, there is a lack of research on male experiences of FP. This scoping review aims to identify bar...
Dendrosomal Curcumin Nanoformulation induces apoptosis via Bax/Bcl-2 in human ovarian cancer OVCAR3 cells [0.03%]
基于树状大分子的姜黄素纳米药物通过Bax/Bcl-2诱导人卵巢癌OVCAR3细胞凋亡
Marziyeh Alizadeh Zarei,Hossein Nikzad,Zahra Shabani et al.
Marziyeh Alizadeh Zarei et al.
Introduction: Curcumin (Cur), a yellow polyphenolic compound derived from the rhizome of turmeric, exhibits potent chemopreventive and chemotherapeutic properties. However, its clinical application as an anticancer agent ...
USP6NL and MSX2 as the novel diagnostic markers in gastric cancer patients [0.03%]
USP6NL和MSX2作为胃癌患者的新型诊断标志物
Zahra Basirat,Negin Taghehchian,Mohammad Reza Abbaszadegan et al.
Zahra Basirat et al.
Gastric cancer (GC) is one of the most frequent gastrointestinal malignancies in the world. WNT signaling pathway has a key role in the occurrence and progression of GC. USP6NL belongs to the GAP protein family that regulates the WNT signal...